(apologies if a duplicate
Subject: Daily Scan of COVID-19 Scientific Publications / survol journalier des publications scientifiques du COVID-19,
2020-09-30
Good afternoon,
There are 861 citations in today’s scan. 437 were considered primary research or review literature.
Highlights today include:
CANADA
·
Qiuyu Jiang
examines how a small-scale non-governmental organization mobilizes community members in Montreal, Canada, to respond to the city’s shortage of personal protective equipment during COVID-19 by making more than 1600 scrub caps for local healthcare workers.
PUBLIC HEALTH INTERVENTION
·
Lim et al
use a discrete event simulation to explore the impact of different permutations of staff roster, including the number of shifts per day, the number of staff on duty per shift, overall number of staff accessible to work in the laboratory, the frequency
of shift changes, fixed work-rest days and split team arrangement on workplace transmission of COVID. A higher rate of transmission was associated with smaller overall staff pool (expressed as multiples of the number of staff per shift), higher number of shifts
per day, higher number of staff per shift, and longer consecutive days worked. Social distancing and PPE use significantly reduced the transmission rate. Laboratories should consider organizing the staff into smaller teams/shift and reduce the number of consecutive
days worked.
TRANSMISSION
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Kotb and Khalil
presents the results of a study of airflow behavior of coughing and sneezing droplets that are produced from a moving passenger in wide-body aircraft cabin section at different velocity rates. The results showed that the airflow of coughing and sneezing
droplets produced from the moving passengers could reach seated passengers; however, sneezed droplets had more harmful impacts than coughed droplets, also both travelled for a long distance inside the cabin. In addition, when comparing the droplets spread
range resulting from the moving passenger and stand-still one, it was found that the quicker the passenger moves, the further the droplets spread.
·
Pavli et al
conduct an extensive epidemiological investigation and
present 5 cases of probable in-flight transmission in Greece.
·
Shao, et al.
combine in situ measurements and computational fluid dynamics simulations, we quantify the exhaled particles from normal respiratory behaviors and their transport under elevator, small classroom, and supermarket settings to evaluate the risk of inhaling
potentially virus-containing particles. Our results show that the design of ventilation is critical for reducing the risk of particle encounters.
EPIDEMIOLOGY
·
Ad’hiah et al
examined the genetic association of ABO blood groups with risk of disease in Iraqi patients. Logistic regression analysis revealed that groups AB and B + AB were significantly associated with increased risk to
develop COVID-19. And also noted that groups A (OR = 14.60), AB (OR = 12.92), A + AB (OR = 14.67), and A + B + AB (OR = 9.67) were associated with increased risk of death in deceased cases. This suggests that
group A may be associated with increased risk of death.
·
He et al.
studied COVID-19 positive (194) and negative (212) patients to analyze bacterial pathogens co-infection. Results showed that 50% of COVID-19 patients were co-infected or carried bacterial pathogens.
·
Invernizzi et al.
screened the fundus of patients with COVID-19 to detect alterations of the retina and its vasculature and to assess possible correlations with clinical parameters. Fifty-four patients and 133 unexposed subjects were enrolled. Retinal findings in COVID-19
included: hemorrhages (9·25%), cotton wools spots (7·4%), dilated veins (27·7%), tortuous vessels (12·9). Both Mean arteries diameter (MAD) and veins diameter (MVD) were higher in COVID-19 patients compared to unexposed subjects.
·
Karb et al
identify shelter characteristics that may be associated with higher transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They conducted a cross-sectional assessment of five congregate shelters in Rhode Island. Thirty-five shelter
residents (11.7%) tested positive for SARS-CoV-2. Shelters with positive cases of SARS-CoV-2 were in more densely populated areas, had more transient resident populations, and instituted fewer physical distancing practices compared to shelters with no cases.
·
Han et al investigate
transmission of COVID-19 in a Spa facility in a local community in Korea.
A cluster of 10 cases occurred in a Spa setting with high temperature and humidity. Three confirmed patients were infected at a Spa facility and 7 confirmed patients were second, third, and fourth generations of transmission.
·
Teixeira da Silva and Tsigaris
model factors influencing COVID-19 mortality across 121 countries by income group. Countries with a higher proportion of people aged 65+ years had a higher fatality rate. Delaying policies for international travel restrictions, public information campaigns,
and testing policies increased the fatality rate. More cumulative tests per million people showed lower mortality rates, while countries where citizens can access more international destinations without a prior visa had higher mortality rates.
CLINICAL DATA
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Faber et al
present a COVID-19 case who developed akinetic‐rigid parkinsonism. As the patient was neurologically normal prior to the COVID‐19 infection, authors conclude that SARS‐CoV‐2 infection is responsible for the parkinsonism.
·
Hartmann et al.
conducted a histopathological and immunohistochemical study to clarify the pathogenesis and pathways involved in COVID-19 myocardial injury. Postmortem minimally invasive autopsies were performed in six patients who died from COVID-19, and the myocardium
samples were compared to a control patient. The subsequent inflammation with associated interstitial edema could explain the myocardial dysfunction and arrhythmias in these patients. The findings also show that COVID-19 myocardial injury may cause myocardial
fibrosis in the long term.
THERAPEUTICS
·
Fu et al.
conducted an open-label randomized trial and found that aerosol inhalation of IFN-κ plus TFF2 in combination with standard care is safe and superior to standard care alone in shortening the time up to viral RNA negative conversion in all clinical samples.
In addition, the patients in experimental group had a significantly shortened CT imaging improvement time than those in control group. This study suggested that this combination treatment is able to facilitate clinical improvement (negative for virus, improvement
by CT, reduced hospitalization stay) and thereby result in an early release from the hospital. These data support the need for exploration with a large-scale trial of IFN-κ plus TFF2 to treat COVID-19.
·
Shalayel, et al.
investigated Vitamin D for its in silico potential inhibition of the binding sites of SARS-CoV-2 endoribonuclease Nsp15. In this study, we selected Remdesivir, Chloroquine, Hydroxychloroquine and Vitamin D to study the potential binding affinity with
the putative binding sites of endoribonuclease Nsp15 of COVID-19. Among the results, Vitamin D was found to have the highest potency with strongest interaction in terms of LBE, lowest RMSD, and lowest inhibition intensity Ki than the other standard compounds.
·
Jeremiah et al
evaluate the antiviral effect of Silver nanoparticles (AgNP). Their results indicate that AgNPs are highly potent microbicides against SARS-CoV-2 but should be used with caution due to their cytotoxic effects and their potential to derange environmental
ecosystems when improperly disposed.
DIAGNOSTICS
·
Zhao et al
reported an ultrasensitive electrochemical detection technology to practicably detect the RNA of SARS-CoV-2 without nucleic acid amplification and reverse-transcription by using a portable electrochemical smartphone. The biosensor showed high specificity
and selectivity during in silico analysis and actual testing.
·
Kerpel et al
assess the diagnostic and prognostic value of chest radiographs (CXR) for coronavirus disease 2019 (COVID-19) at presentation. The overall RALE score failed to identify COVID-19 patients at presentation. They determined that chest radiography was found
not to be a valid diagnostic tool for COVID-19, as normal or near-normal CXRs are more likely early in the disease course.
CORONAVIROLOGY
·
Nelson et at
study the overlapping genes (OLG) present in coronaviruses. They characterize ORF3d, a novel OLG in SARS-CoV-s also present in Guangxi pangolin-CoVs but not other closely related pangolin-CoVs or bat-CoVs. The results highlight the importance of OLGs.
·
Sabino et. al.
evaluated the inactivation kinetics and reported the UV-C lethal doses (LD) for SARS-CoV-2. Authors verified that within less than a second, UV-C irradiation was able to inactivate more than 99 % of SARS-CoV-2 viral particles.
In fact, LD90 and LD99.999 were achieved at 0.016 and 108.714 mJ/cm2 (0.01 and 49.42 s) respectively. In summary, the findings can help scientific community and health authorities to develop safe and effective protocols to reduce the dissemination of SARS-CoV-2
during this global health crisis
ECONOMICS
·
Tan-Torres Edejer et al.
estimate the additional healthcare costs of COVID-19 response in the status quo scenario, vs. increase or decrease in transmission by 50%. Cost estimates are US$52·45 billion over 4 weeks, at $8·60 per capita. Under decreased or increased transmission
scenarios, the totals were $33·08 billion and $61·92 billion, respectively. By percentage of the overall cost, case management (54%), maintaining essential services (21%), rapid response and case investigation (14%), and infection prevention and control (9%)
were the main cost drivers.
PUBLIC HEALTH RESPONSE
·
Head et al.
conducted a survey (N = 3,159) with U.S. adults in May 2020 assessing SARS-CoV-2 vaccine intentions, intentions with a provider recommendation, and sociodemographic and psychosocial variables. Participants had high SARS-CoV-2 vaccine intentions, which
increased significantly with a provider recommendation. Less education and working in health care were associated with lower intent, and liberal political views, altruism, and COVID-19-related health beliefs were associated with higher intent.
·
Tavares et al.
examine teleworking carried out in Portuguese communities as a result of the state of emergency from the COVID-19 pandemic. Findings indicate adapting to teleworking was easy or very easy and happened quickly. The main difficulties encountered by the
individuals were the lack of professional interaction/communication with coworkers, the lack of resources related to support infrastructures, such as the internet or a printer, and the reconciliation of teleworking with family life/household chores/dedication
to children and time/schedule management.
Regards,
Lisa Waddell, Tricia Corrin, Rukshanda Ahmad, Robyn Odell, Maribeth Mitri, Julie Theriault, Dobrila Todoric, Alejandra Dubois, Christina Bancej, Austyn Baumeister, Anam Khan, Musaab Younis, Lien Mi Tien, Dima Ayache, Angela Sloan, Kaitlin
Young, Chatura Prematunge, Ainsley Otten, Irene Yong, Drew Greydanus, Shalane Ha, Alex Gilbert, Jessie Varga, Vanessa Zubach, Meenu Sharma, Kristyn Burak
Focus areas: Modelling/ prediction, Epidemiology, Transmission, Clinical data, Surveillance, Coronavirology, Diagnostics / Pathogen detection, Therapeutics,
Vaccine Research, Public health interventions, Public Health response, Public Health Priorities, IPAC, Health care response, immunology, economics, animal model, zoonoses, Review Literature, Commentary/Editorial, news
Domaines cibles: Modélisation/prédiction, Épidémiologie, Transmission, Données cliniques, Surveillance, Coronavirologie, Diagnostics
/ Détection d'agents pathogènes, Thérapeutique, Recherche sur les vaccins, Interventions de santé publique, Priorités de santé publique, PCI,
Réponse des soins de santé, immunologie, économie, modèle animal, zoonoses, Revue de littérature, Commentaire/Éditorial, journaux
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PUBLICATIONS |
AUTHORS / AUTEURS |
SOURCE |
FOCI / DOMAINE |
SUMMARY / SOMMAIRE |
Case study: Spark GPU-enabled framework to control COVID-19 spread using cell-phone spatio-temporal data |
Abdallah, HS, Khafagy, et al |
Computers, Materials and Continua |
Public health interventions*| Interventions de santé publique |
This research presents an innovative case study based on big data processing techniques to build a complete tracking
system able to identify the central areas of infected/suspected people, and the new suspected cases using health records integration with mobile stations spatio-temporal data logs. The main idea is to identify the positive cases historical movements by tracking
their phone location for the last 14 days (i.e., the virus incubation period). Then, by acquiring the citizen’s mobile phone locations for the same period, the system will be able to measure the Euclidean distances between positive case locations and other
nearby people to identify the in-contact suspected-cases using parallel clustering and classification techniques. Moreover, the daily change of the clusters size and its centroids will be used to predict new regions of infection, as well as, new cases. |
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Recognition of Corona virus disease (COVID-19) using deep learning network |
Abdulmunem, AA, Abutiheen, et al |
International Journal of Electrical and Computer Engineering |
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection d'agents pathogènes |
Corona virus disease (COVID-19) has an incredible influence in the last few months. It causes thousands of deaths in round the world. This make a rapid
research movement to deal with this new virus. As a computer science, many technical researches have been done to tackle with it by using image processing algorithms. In this work, we introduce a method based on deep learning networks to classify COVID-19
based on x-ray images. Our results are encouraging to rely on to classify the infected people from the normal. We conduct our experiments on recent dataset, Kaggle dataset of COVID-19 X-ray images and using ResNet50 deep learning network with 5 and 10 folds
cross validation. The experiments results show that 5 folds gives effective results than 10 folds with accuracy rate 97.28%. © 2021 Institute of Advanced Engineering and Science. All rights reserved. |
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32893072; Myopathy associated with serious SARS-CoV-2 infection |
Abenza Abildúa, MJ, Ramírez Prieto, et al |
Neurologia |
Clinical data| Données cliniques |
This editorial is in Spanish and presents the case of a 45-year-old woman, with no relevant history, who was diagnosis with acute inflammatory myopathy
due to the SARS-CoV-2 virus. |
|
Ad’hiah, AH, Allami, et al |
Egyptian Journal of Medical Human Genetics |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
This study sought to understand the genetic association (associated with ABO blood groups) with risk of disease in Iraqi patients. ABO blood groups were
determined in 300 hospitalized COVID-19 Iraqi patients (159 under therapy, 104 recovered, and 37 deceased) and 595 healthy blood donors. Two outcomes of COVID-19, recovery and death, were explored. Logistic regression analysis revealed that groups AB and
B + AB were significantly associated with increased risk to develop COVID-19 (OR = 3.10; 95% CI 1.59–6.05; pc = 0.007 and OR = 2.16; 95% CI 1.28–3.63; pc = 0.028, respectively). No ABO-associated risk was observed in recovered cases. On the contrary, groups
A (OR = 14.60; 95% CI 2.85–74.88; pc = 0.007), AB (OR = 12.92; 95% CI 2.11–79.29; pc = 0.042), A + AB (OR = 14.67; 95% CI 2.98–72.33; pc = 0.007), and A + B + AB (OR = 9.67; 95% CI 2.02–46.24; pc = 0.035) were associated with increased risk of death in deceased
cases. |
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Agarwal, N, Harikar, et al |
International Journal of Diabetes in Developing Countries |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
A cross-sectional, observational study was done to assess determinants of stress and its impact on glycemic control in adolescents and young adults (aged
12–24 years) living with T1D in India. A total of 89 participants (46 males, mean age 19.61 ± 3.8 years) with T1D completed the survey. Age (r = 0.325, p = 0.005) and HBA1C level within the preceding 3 months (r = 0.274, p = 0.036) correlated positively with
Perceived Stress Scale (PSS-10) scores. There was a statistically significant difference in PSS-10 score based on gender (t(70) = − 2.147; p = 0.035), education (F (4,67) = 4.34, p = 0.003), and occupation (F(3,68) = 4.50, p =.006). On multiple linear regression,
gender, occupation, and HbA1C were the significant determinants of PSS-10 (F(3,55) = 12.01, p < 0.001, R2 = 0.363). One-way ANOVA showed a significant impact of mean PSS-10 score on the glycemic control (F(2,69) = 3.813, p = 0.027). An increased prevalence
of stress was seen among Indian adolescents and young adults living with T1D. Female gender, salaried individuals, and pre-existing poorly controlled diabetes contributed to an increased risk of stress. |
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Infection Risk Score: Identifying the risk of infection propagation based on human contact |
Agarwal, Rachit, Banerjee, et al |
arXiv |
Epidemiology| Épidémiologie Public health interventions*| Interventions de santé publique |
This paper introduces an infection risk score that provides an estimate of the infection risk arising from human contacts.
Using a real-world human contact dataset, the authors showed that the proposed risk score can provide a realistic estimate of the level of risk in the population. Also described how the proposed infection risk score can be implemented on smartphones. Finally,
identified representative use cases that can leverage the risk score to minimize infection propagation. |
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Agarwal, V, Gupta, et al |
The journal of the Royal College of Physicians of Edinburgh |
Public Health response| Interventions de santé publique |
An online survey featuring 33 questions was distributed amongst undergraduate medical students to understand
their knowledge, attitude and preparedness towards Covid-19 . Three-quarters of students were not aware of the treatment guidelines for Covid-19 and one quarter were unaware of the precautions needed while managing patients with the disease (Supplementary
Table 2, online). Moreover, 29.1% were unaware that Covid-19 causes an asymptomatic or minor illness in most young individuals. nearly 20% were not sure if they had been in contact with or cared for someone with Covid-19 in the prior two weeks, and
another 10% continued to attend clinical rotations, ignoring their symptoms suggestive of Covid-19. Moreover, over two-thirds (69.3%) expressed reluctance to attend clinics from fear of getting infected or passing the infection on to others. Besides, 40.6%
were not up-to-date on Covid-19, and most (78.9%) resorted to social media for information on Covid-19. |
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Agnoletti, M, Manganelli, et al |
Landscape and Urban Planning |
Epidemiology| Épidémiologie |
This study was conducted to understand whether there is a correlation between the number of infections and the different
rural landscapes in Italy. Found that provinces with 10% more type C (hilly areas) and type D (high hills and mountains with forests and protected areas) areas exhibit on average 10% fewer cases of contagion. The result is statistically significant, after
controlling for demographic, economic and environmental characteristics of the provinces. |
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Viroinformatics-based investigation of SARS-CoV-2 core proteins for
potential therapeutic targets |
Agrawal, Lokesh, Poullikkas, et al |
arXiv |
Coronavirology| Coronavirologie Therapeutics| Thérapeutique |
In the present study, more than 60 antiviral drugs already available on the market, were chosen after literature survey.
These candidate drugs were ranked based on their potential to interact with the Spike protein and RdRp (RNA-dependent RNA polymerase) of SARS-CoV-2. Additionally, the mechanism of their action as well as how the virus infection can utilize Hemoglobin to decrease
the oxygen level in blood is explained. Moreover, multiple sequence alignments of the Spike protein with 75 sequences of different viruses from the Orthocoronavirinae subfamily were performed. This multidimensional study opens a new layer of understanding
about the most effective drug-targetable sites on the Spike protein of SARS-CoV-2. |
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Ahmed, HO |
Annals of Medicine and Surgery |
Public Health response| Interventions de santé publique |
The prospective cross-sectional case series study aimed to figure out whether social isolation during the COVID-19
quarantine is consistent and associated with emotional eating and gaining weight or not. An individual face-to-face interview was conducted with 765 patients who have visited the bariatric clinic in Sulaimani city. Results showed that social distancing and
self-isolation in the last COVID-19 outbreak influenced weight gain, weight gain of less than 2 kg was observed among almost all patients who gained weight (98.05%). The patients who were gain more than 3 kg were mostly females or/and from the center of large
cities. |
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The Prevalence and Predictors of Post-Stroke Depression and Anxiety During COVID-19
Pandemic |
Ahmed, ZM, Khalil, et al |
Journal of Stroke and Cerebrovascular Diseases |
Public Health response| Interventions de santé publique |
This study evaluated the impact of COVID-19 pandemic on the rates of post-stroke depression (PSD) and anxiety (PSA).
Among 50 participants (28 males), clinically significant PSD was found in 36%, while PSA in 32%. PSD associated with higher NIHSS (P < 0.001); lower MSPSS (P = 0.003); higher mRS (P = 0.001); and discontinuation of rehabilitation (P = 0.02). PSA was associated
with higher TSH (P = 0.01); lower MSPSS (P = 0.03); while discontinuation of rehabilitation was related to less PSA (P = 0.034). Multivariate analysis showed that NIHSS (OR: 1.58, 95% CI: 742–3.37; P = 0.01); and MSPSS score (OR: 0.66, 95%CI: 0.47–0.94; P
= 0.002) were associated with PSD; while PSA was related to TSH level (OR: 8.32, 95%CI:1.42–47.23; P = 0.02), and discontinuation of rehabilitation (OR: -0.96, 95%CI: -1.90–0.02; P = 0.04) |
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Aita, A, Basso, et al |
Clinica Chimica Acta |
Diagnostics / Pathogen detection| Diagnostics / Détection d'agents pathogènes |
This study aims to verify whether standardized saliva collection is suitable for SARS-CoV-2 molecular detection and
IgA measurement. NP-swabs and saliva were both SARS-CoV-2 positive in 7 (16%) or both negative in 35 (82%) out of 43 patients successfully included in the study. NP-swabs and saliva results did not perfectly match in one patient (saliva positive, NP-swab
negative). Positive molecular results were significantly associated with disease duration (p = 0.0049). 326/326 screening subjects were SARS-CoV-2 negative on both NP-swabs and saliva. Among the 27 saliva samples tested for IgA, 18 were IgA positive. Salivary
IgA positivity was associated with pneumonia (p = 0.002) and CRP values (p = 0.0183), not with other clinical and molecular data, or with serum immunoglubulins. |
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The assessment of the relationship between abo blood groups and COVID-19 infection |
Aktimur, SH, Sen, et al |
UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
The aim of this study is to determine the relationship between ABO blood group and susceptibility to COVID-19 infection
and whether the blood group will be a biomarker for COVID-19 infection. A total of 179 patients with confirmed COVID-19 and 5200 healthy control patients were included in the study. Patients with COVID-19 showed a distribution of 62.01% in group A,9.50% in
group B, 8.94% in group AB and 19.55% in group O. In group A, length of stay in Intensive Care Unit was longer (10.42±11.61 days; p= 0.013). Compared to the blood groups of the healthy control group, COVID-19 patients had higher A blood group than the healthy
group (62& vs.46.6%; p< 0.001) and lesser of the O blood group (19.6% vs. 34.7%; p< 0.001).Blood group A can be used as a predictive biomarker for COVID-19 disease.In addition, we concluded that the group A had a higher risk for COVID-19 disease and severity. |
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Clinical characteristics of hospitalized and home isolated COVID-19 patients with type 1 diabetes |
Al Hayek, AA, Robert, et al |
Diabetes and Metabolic Syndrome: Clinical Research and Reviews |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
This study examined the clinical features of COVID-19 patients with type 1 diabetes (T1D) under hospitalization and
home isolation conditions. The most common symptoms observed among the hospitalized patients were nausea and vomiting (71.4%; 5/7), followed by fever (57.1%; 4/7), cough (42.8%; 3/7), sore throat (42.8%; 3/7), abdominal pain (42.8%; 3/7) and dyspnea (42.%;
3/7). The most common reasons for hospitalization were diabetic ketoacidosis (71.4%; 5/7) followed by bacterial pneumonia (14.3%; 1/7), fever (14.3%; 1/7), sore throat (14.3%; 1/7), severe hyperglycemia (14.3%; 1/7) and COVID-19 pneumonia (14.3%; 1/7). Except
the severity of COVID-19 (p = 0.0001), none of the demographic and clinical parameters indicated statistically significant differences between patients requiring hospitalization and home isolation. |
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Alagarasu, K, Potdar, et al |
The Indian journal of medical research |
Diagnostics / Pathogen detection| Diagnostics / Détection d'agents pathogènes |
This correspondence the present the study that explored the utility of protease enzyme and dithiothreitol (DTT) treatment
prior to heat inactivation in releasing the viral RNA and its subsequent use in real-time reverse transcription-polymerase chain reaction (RT-qPCR) for detection of the SARS-CoV-2. The results suggested that the modified heat inactivation protocol with the
addition of protease and DTT followed by dilution might have resulted in reducing the presence of inhibitors for RT-qPCR. |
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Aletta, F, Oberman, et al |
Noise Mapping |
Public Health response| Interventions de santé publique |
This study aims to understand how the person-level experience of the urban soundscape has been affected and how these
affects differ across urban space typologies. Taking London as a case study, a series of 30-second binaural recordings were taken at 11 locations representing a cross-section of urban public spaces with varying compositions of sound sources during Spring 2019
(pre-lockdown, N = 620) and Spring 2020 (during-lockdown, N = 481). Five acoustic and psychoacoustic metrics (LAeq, LA10, LA90, Loudness, Sharpness) were calculated for each recording and their changes from the pre-lockdown scenario to the lockdown scenario
are investigated. Clustering analysis was performed which grouped the locations into 3 types of urban settings based on their acoustic characteristics. An average reduction of 5.4 dB (LAeq) was observed, however significant differences in the degree of reduction
were found across the locations, ranging from a 10.7 dB to a 1.2 dB reduction. This study confirms the general reduction in noise levels due to the nationally imposed lockdown measures, |
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Alharthy, A, Faqihi, et al |
Journal of epidemiology and global health |
Clinical data| Données cliniques Healthcare Response | Réponse des soins de santé |
This editorial present feasibility data from 30 patients with COVID-19 and ARF who received H-CPAP ( Continuous Positive
Airway Pressure via a Helmet) (n = 15) and High Flow Nasal Cannula (HFNC) (n = 15) in Intensive Care Unit (ICU). Preliminary data suggests that HFNC is feasible in patients with ARF from COVID-19 pneumonia, and effective in maintaining oxygenation. H-CPAP
is similarly effective in terms of oxygenation but could not be maintained in over half-of-all patients when proned. |
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Impact of novel coronavirus (COVID-19) on daily routines and air environment: evidence from Turkey |
Ali, H, Yilmaz, et al |
Air Quality, Atmosphere and Health |
Public Health response| Interventions de santé publique Economics | Économie |
This study mainly investigates the impact of this pandemic on the daily routines of Turkish. Results reveal that increasing
unemployment, decrease in air contamination, high stress and depression, a slowdown in the economic growth, and the tourism industry are profoundly affected due to the COVID-19 in Turkey. Furthermore, on the one hand, the consequences of the pandemic are segregated
into social problems and psychological issues in daily routines. On the other hand, they have shown a positive impact on the air environment. |
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Alimohamadi, Y, Holakouie-Naieni, et al |
Risk Management and Healthcare Policy |
Epidemiology| Épidémiologie Public health interventions*| Interventions de santé publique |
This study assessed the effectiveness of social distancing measures on the COVID-19 incidence and mortality in Iran.
After the implementation of social distancing, the trend of both daily new cases and deaths due to COVID-19 was decreasing (ß = −1.70 (95% CI = −2.30 – −1.10; P < 0.001])) and (ß = −0.07 (95% CI = −0.10 − −0.05; P < 0.001], respectively))]. |
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Alkhaibary, A, Abbas, et al |
World Neurosurgery |
Clinical data| Données cliniques |
This report describes the clinical presentation, radiological findings, and outcome of large-vessel occlusion in a
young patient who was later diagnosed with COVID-19. Although rare, patients with COVID-19 can present with large-vessel occlusion. Prompt identification of COVID-19–related coagulopathy is essential to assess young patients with clinical manifestations of
infarction. |
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Almahboub, SA, Algaissi, et al |
Frontiers in Microbiology |
Diagnostics / Pathogen detection| Diagnostics / Détection d'agents pathogènes |
Here, we describe a detailed protocol of a safe and convenient assay to generate vesicular stomatitis virus (VSV)-based
pseudoviruses to evaluate and measure nAbs against highly pathogenic CoVs. The protocol covers methods to produce VSV pseudovirus bearing the S protein of the Middle East respiratory syndrome-CoV (MERS-CoV) and the severe acute respiratory syndrome-CoV-2 (SARS-CoV-2),
pseudovirus titration, and pseudovirus neutralization assay. Such assay could be adapted by different laboratories and researchers working on highly pathogenic CoVs without the need to handle live viruses in the BSL-3 environment. |
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The effects of COVID-19 on job security and unemployment in Portugal |
Almeida, F, Santos, et al |
International Journal of Sociology and Social Policy |
Public Health response| Interventions de santé publique |
This short communication aims to explore and synthesize the main effects of COVID-19 on the labor market in Portugal
regarding the dimensions related to job security and unemployment. The findings indicate that the impact on the labor market is very asymmetric regarding geographical regions, sectors of activity, age groups and the nature of labor ties. The most touristic
regions and those with a strong dependence on the exterior are the most affected. Young people and women with unstable employment relationships and in temporary work situations are also particularly vulnerable. |
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Al-Terehi, M, Alkaim, et al |
Annals of Tropical Medicine and Public Health |
Coronavirology| Coronavirologie |
This study introduced an in silico approach to design potential siRNA molecules of SARS-CoV-2 targeting Virus structural
genes, as a preliminary opinion for COVID-19 inhibition. The structural genes included spike protein (S), envelope protein (E), membrane protein (M) and nucleocapsid protein (N). The sequence data of SARS-CoV-2 (MN908947.3) used for siRNA designing by siDIRECT
bioinformatics tools, the results show there were 177, 539, 27 and 106 siRNA molecules of N, S, E and M genes respectively, then the choosing of some siRNA molecules Tm, low off-targets effect and mismatches nucleotides resulted 18, 24, 2 and 9 siRNA molecules
of N, S, E and M genes respectively, the siRNA for the structural proteins were low Tm, low off-targets effect, targeted more than one region at same gene, and molecule sequence started from 30-100 n downstream gene beginning. Study concluded that the dealing
with short genes of SARS-CoV-2 was more benefits for siRNA design and targeted more than one gene at the same time may introduce promising results in vivo experiments. |
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SARS-CoV-2 leading to acute pancreatitis: an unusual presentation |
Alves, AM, Yvamoto, et al |
Brazilian Journal of Infectious Diseases |
Clinical data| Données cliniques |
Herein we report the case of a patient with COVID-19 who developed severe acute pancreatitis. |
|
Early recovery patterns of olfactory disorders in COVID-19 patients; a clinical cohort study |
Amer, MA, Elsherif, et al |
American Journal of Otolaryngology - Head and Neck Medicine and Surgery |
Clinical data| Données cliniques |
This study aimed to delineate the different patterns of olfactory disorders recovery in patients with COVID-19. Ninety
six patients completed the study with mean age 34.26 ± 11.91 years. Most patients had sudden anosmia 83%. Loss of smell was accompanied by nonspecific inflammatory symptoms as low-grade fever (17%) and generalized body ache (25%). Nasal symptoms were reported
by 33% of patients. Some patients reported comorbidities as D.M (16%), hypertension (8%) or associated allergic rhinitis (25%), different patterns of olfactory recovery showed 32 patients experiencing full recovery (33.3%) while, 40 patients showed partial
recovery (41.7%) after a mean of 11 days while 24 patients (25%) showed no recovery within one month from onset of anosmia. |
|
Anastasiadou, E, Chrissos Anestis, et al |
Cell |
Public Health response| Interventions de santé publique |
The purpose of this study is to investigate the changes that have taken place in consumer behavior due to the fear,
caused by the spread of the coronavirus, in parallel to studying how supermarket activities have changed during the pandemic. Differences in consumer behavior and supermarket activities in both countries based on different mentalities and different experiences
were identified. Similarities in consumer behavior, but with different motives, were also discovered. Research limitations/implications: Retailing practitioners and communication executives can apply the findings to manage sales in a time of sharp, unpredictable
crisis. The paper aims at integrating existing literature for the academic community and contributes with implications for practitioners and policymakers to reduce crisis risks. |
|
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32665476; Elective Tracheotomy in COVID-19 Patients: A Team-Based Approach |
Ander, M, Yang, et al |
Anesthesia and Analgesia |
Healthcare Response | Réponse des soins de santé |
Herein we describe techniques used that resulted in efficient and safe performance of tracheotomies in COVID-19 patients.
Our goal was to perform 3–5 COVID-19 tracheostomies in a day at least once per week, and we felt that the negative pressure bronchoscopy laboratory would be our optimal procedural site location. |
|
Analyzing the spatial determinants of local Covid-19 transmission in the United States |
Andersen, LM, Harden, et al |
Science of the Total Environment |
Epidemiology| Épidémiologie |
The objective of the study is to understand the spatial determinants of the pandemic in counties across the U.S. by
comparing socioeconomic variables to case and death data from January 22nd to June 30th 2020. A cluster analysis was performed to examine areas of high-risk, followed by a three-stage regression to examine contextual factors associated with elevated risk patterns
for morbidity and mortality. The factors associated with community-level vulnerability included age, disability, language, race, occupation, and urban status. |
|
Ash’aari, ZH, Aris, et al |
Aerosol and Air Quality Research |
Public health interventions*| Interventions de santé publique |
This study evaluated temporal and spatial variations of four major air pollutant concentrations across Malaysia before
(March 4-17, 2020) and during the implementation of different phases of Movement Control Order (MCO) (March 18-May 20, 2020) from 65 official regulatory air quality stations. Results showed that restriction in daily and economic activities has remarkably reduced
the air quality in all sub-urban, urban, and industrial settings with relatively small contributions from meteorological conditions. Overall, compared to before MCO, average concentrations of PM2.5, CO, and NO2 reduced by 23.1%, 21.74%, and 54.0%, respectively,
while that of SO2 was constant. The highest reduction of PM2.5, CO, and NO2 were observed in stations located in urban setting, where 63% stations showed significant reduction (p < 0.05) for PM2.5 and CO, while all stations showed significant reduction in
NO2 concentrations. |
|
|
Atallah, B, El Nekidy, et al |
Thrombosis Journal |
Clinical data| Données cliniques |
In this case series, we report four cases of venous thromboembolism and 1 case of arterial thrombotic event, in patients
treated with standard or intensified prophylactic doses of unfractionated heparin or low molecular weight heparin at our institution. |
|
|
Aydın, M, Dülger, et al |
Eastern Journal of Medicine |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
In this retrospective study we included 39 COVID 19 patients and 180 age-matched control subjects to compare rate of
intestinal metaplasia. All statistical analyses were performed with SAS software (SAS Institute, Cary, N.C.). The clinical and radiological characteristics of patients were compared using Student's t-test. Intestinal metaplasia was found in 11 (28%) of 39
patients while in 7 (3,9%) of 181 controls, which meant a statistical significance (p0,05). We found that GIM is a premalignant condition that can lead to COVID 19 infection. |
|
|
Azzam, NA, Aljebreen, et al |
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association |
Clinical data| Données cliniques |
We aimed to evaluate health-related quality of life (HRQoL) in inflammatory bowel disease (IBD) patient's pre- and
post-COVID-19 pandemic using the IBD-disk questionnaire and explore associations between socio demographic factors, disease types, severity and impaired HRQoL in patients with IBD. A total of 59 IBD patients (40 Crohn's disease, 19 Ulcerative colitis) with
a mean disease duration of 3.5 years were included. Most of the patients (77.97%) were on biologics while 35.59% were on immune modulators, 16.94% on 5-ASA, and 3.38% were on corticosteroids. There was no difference between any of the 10 IBD-disk variables
pre and post-COVID-19 pandemic apart from the perception of body image, where there was a slightly more negative perception with an increase from 2.53 to 3.39 (P = 0.05) There was no significant difference in HRQoL between patients with ulcerative colitis
and Crohn's disease in any of domains. |
|
|
Targeting SARS-CoV-2 Main Protease: A Computational Drug Repurposing Study |
Baby, K, Maity, et al |
Archives of Medical Research |
Coronavirology| Coronavirologie Therapeutics| Thérapeutique |
To target Mpro and inhibit it, we accomplished the virtual screening of US-FDA approved drugs using well-known drug
repurposing approach by computer-aided tools. The docking and molecular interactions studies, five drugs emerged as potential hits by forming hydrophilic, hydrophobic, electrostatic interactions. The drugs such as arbutin, terbutaline, barnidipine, tipiracil
and aprepitant identified as potential hits. Among the drugs, tipiracil and aprepitant interacted with the Mpro consistently, and they turned out to be most promising. |
|
Identification of TMEM106B as proviral host factor for SARS-CoV-2 |
Baggen, Jim, Persoons, et al |
bioRxiv |
Coronavirology| Coronavirologie |
To identify host factors that support coronavirus infection, we performed genome-wide functional genetic screens with
SARS-CoV-2 and the common cold virus HCoV-229E in non-transgenic human cells. These screens identified PI3K type 3 as a potential drug target against multiple coronaviruses. We discovered that the lysosomal protein TMEM106B is an important host factor for
SARS-CoV-2 infection. Furthermore, we show that TMEM106B is required for replication in multiple human cell lines derived from liver and lung and is expressed in relevant cell types in the human airways. Our results identify new coronavirus host factors that
may potentially serve as drug targets against SARS-CoV-2 or to quickly combat future zoonotic coronavirus outbreaks. |
|
Bai, Y, Jia, et al |
|
Public Health response| Interventions de santé publique |
Our study is intended to develop a dynamic topic analysis system to monitor the evolution of the large-scale text data
topics and assist with the social management and policymaking. This paper explores CBC news articles using Dynamic Topic Model (DTM) and captures the impact of COVID-19 on various aspects and the development of specific events. The experimental results demonstrate
the effectiveness of our system for discovering and tracking the evolving topics. This system also plays an important role to improve the awareness of the public and serves as an analysis platform for government. |
|
|
The assessment of lifestyle changes during the COVID-19 pandemic using a multidimensional scale |
Balanzá-Martínez, V, Kapczinski, et al |
Revista de Psiquiatria y Salud Mental |
Public Health response| Interventions de santé publique |
An online survey was conducted among the general population living in Spain during the COVID-19 home-isolation. A total
of 1254 individuals completed the survey over the first week of data collection. Most participants reported substantial changes on outdoor time (93.6%) and physical activity (70.2%). Moreover, about one third of subjects reported significant changes on stress
management, social support, and restorative sleep. Several demographic and clinical factors were associated to lifestyle scores. In the multivariate model, those independently associated with a healthier lifestyle included substantial changes on stress management
(p < 0.001), social support (p = 0.001) and outdoor time (p < 0.001), amongst others. In contrast, being an essential worker (p = 0.001), worse self-rated health (p < 0.001), a positive screening for depression/anxiety (p < 0.001), and substantial changes
on diet/nutrition (p < 0.001) and sleep (p < 0.001) were all associated with poorer lifestyles. |
|
Bardají, A, Carrasquer, et al |
Revista espanola de cardiologia |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
Our objective was to analyze myocardial injury and its prognostic implications in patients with and without COVID-19
infection treated in the same period of time. In total, 433 patients were distributed among the following groups: confirmed COVID-19 (n = 186), 22% with myocardial injury (n = 41); and ruled out COVID-19 (n = 247), 21.5% with myocardial injury (n = 52). The
confirmed and ruled out COVID-19 groups had a similar age, sex, and cardiovascular history. Mortality was significantly higher in the confirmed COVID-19 group than in the ruled out group (19.9% vs 5.3%, P < .001). In Cox multivariate regression analysis, cardiac
troponin I was a predictor of mortality in both groups (confirmed COVID-19 group: HR, 3.54; 95%CI, 1.70-7.34; P = .001; ruled out COVID-19 group: HR, 5.57; 95%CI, 1.70-18.20; P = .004). The predictive model analyzed by ROC curves was similar in the 2 groups
(P = .701), with AUCs of 0.808 in the confirmed COVID-19 group (0.750-0.865) and 0.812 in the ruled out COVID-19 group (0.760-0.864). |
|
|
Barry, M, AlMohaya, et al |
Journal of epidemiology and global health |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
The objective of this report is to describe the characteristics and outcome observed among 99 hospitalized COVID-19
patients in the largest academic hospital in KSA, and assess co-infection with the Middle East Respiratory Syndrome Coronavirus (MERS-CoV). The 99 hospitalized COVID-19 patients included in this analysis constitute 16% of 632 positive SARS-CoV-2 among 6633
persons who were tested at the KSUMC (positivity rate, 9.4%). We observed no MERS-CoV co-infection in this early cohort of hospitalized COVID-19 patients who were relatively young, more than half had comorbid conditions, presented with fever and/or cough,
an abnormal chest X-ray, lymphopenia, and high inflammatory markers. Given MERS-CoV endemicity in the country, co-monitoring of MERS-CoV and SARS-CoV-2 coinfection is critical. |
|
|
A Tethered Ligand Assay to Probe the SARS-CoV-2 ACE2 Interaction
under Constant Force |
Bauer, MagnusS, Gruber, et al |
bioRxiv |
Coronavirology| Coronavirologie |
Here, we introduce a tethered ligand assay that comprises the RBD and the ACE2 ectodomain joined by a flexible peptide
linker. Using specific molecular handles, we tether the fusion proteins between a functionalized flow cell surface and magnetic beads in magnetic tweezers. We observe repeated interactions of RBD and ACE2 under constant loads and can fully quantify the force
dependence and kinetics of the binding interaction. Our results suggest that the SARS-CoV-2 ACE2 interaction has higher mechanical stability, a larger free energy of binding, and a lower off-rate than that of SARS-CoV-1, the causative agents of the 2002-2004
SARS outbreak. In the absence of force, the SARS-CoV-2 RBD rapidly (within ≤1 ms) engages the ACE2 receptor if held in close proximity and remains bound to ACE2 for 400-800 s, much longer than what has been reported for other viruses engaging their cellular
receptors. |
|
Bedi, JS, Dhaka, et al |
Aerosol and Air Quality Research |
Public health interventions*| Interventions de santé publique |
The present study aims to assess the changes in air quality before and during lockdown in the four major metropolitan
cities of India viz., Delhi, Mumbai, Kolkata and Chennai. The data on major air quality parameters and meteorological parameters was collected for 15 days before lockdown (i.e., March 10th–March 24th, 2020) and 15 days after implementation of lockdown (25th
March–April 8th, 2020). The lockdown measures reflected a significant reduction in air pollutants, most significant fall was estimated for NO2 (29.3–74.4%) while the least reduction was noticed for SO2. On the contrary, levels of ground level ozone were found
to be increased (except in Mumbai), could be related to the lower utilization of O3 owing to decrease of NOx in the environment. |
|
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Pulmonary Thrombosis or Embolism in a Large Cohort of Hospitalized Patients With Covid-19 |
Benito, N, Filella, et al |
Frontiers in Medicine |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
Methods: We prospectively collected data from all consecutive patients with laboratory-confirmed Covid-19 admitted
to the Hospital de la Santa Creu i Sant Pau, a university hospital in Barcelona, between March 9 and April 15, 2020. Patients with suspected PE, according to standardized guidelines, underwent CT pulmonary angiography (CTPA). Results: Patients with PE were
older, and they exhibited lower PaO2:FiO2 ratios and higher levels of D-dimer and C-reactive protein (CRP). They more often required admission to ICU and mechanical ventilation, and they often had longer hospital stays, although in-hospital mortality was no
greater than in patients without PE. |
|
Intravenous chemotherapy adherence of cancer patients in time of covid-19 crisis |
Beypinar, I, Urun, et al |
UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi |
Healthcare Response | Réponse des soins de santé |
The records of patients who have active cancer treatment in the department of medical oncology retrospectively analyzed.
The age, gender, diagnosis, chemotherapy type, rendezvous, and coming dates recorded. Four chemotherapy delays were observed out of 52 patients before the 11th of March 2020, while 43 chemotherapy delays occurred out of 107 patients after the first COVID-19
case and the restrictions in Turkey. Twenty patients had treatment delay without reason and did not show up for treatment on the day of chemotherapy. The treatment delays without reasons are significantly different in the pre and post COVID-19 pandemic era. |
|
Does Karen wear a mask? The gendering of COVID-19 masking rhetoric |
Bhasin, T, Butcher, et al |
International Journal of Sociology and Social Policy |
Public Health response| Interventions de santé publique |
Purpose: This paper asks how values and beliefs around gender influence social norms regarding masking. Specifically,
the paper explores how the gendered meme “Karen” fits into social media discussions on support for and opposition to the wearing of masks to fight the spread of COVID-19. Design/methodology/approach: The authors analyze tweets containing the hashtags #Masks4All
and #NoMasks over a three-week period, using adjacent hashtag analysis to determine the terms most associated with Karen in the pro and anti-mask communities associated with these hashtags. Findings: Anti-maskers reference Karen more often than pro-maskers,
although she is presented in negative terms with gendered overtones by those on both sides of the masking debate. Originality/value: The paper highlights how hypermasculinity rhetoric impedes social change that normalizes mask wearing. © 2020, Emerald Publishing
Limited. |
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Prediction of COVID-19 Outbreak in India adopting bhilwara model of Containment |
Bhati, A, Jagetiya, et al |
|
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie Public health
interventions*| Interventions de santé publique |
This paper has described the Bhilwara model and compare the model with India COVID-19 outbreak lockdown along with
a prediction for a reduction in the number of upcoming cases with its implementation. In experimentation, the Bhilwara model is simulated using 3rd-degree polynomial curve fitting techniques, and the mean growth rate of infection is calculated on the COVID-19
spread curve for a group of days depicting the effect of policies defined by Bhilwara administration. Using calculated mean growth rate, COVID-19 spread is predicted with 3rd-degree polynomial regression utilizing a dataset of all states of India. Results
found that with the implementation of the Bhilwara model all over India, the infection transmission rate is reduced to a significant level. Results motivate government authorities to implement new policies and adaption of the Bhilwara model of containment
to flatten the COVID-19 outbreak curve. |
|
Bhattacharyya, D, Kumari, et al |
International Journal of Current Research and Review |
Epidemiology| Épidémiologie |
This paper gives the best way to prevent and reduce transmission is to be well educated about the COVID-19 infection,
its causes, and its spread. Method: The study aimed to develop a statistical model to predict how the cases are growing exponentially in various parts of the world. Even after starting from a low base, there is no proper statistical analysis of cases we can
expect. It is an ambiguous thing that numbers of cases are exponentially increasing. We have analyzed the mortality rate, the number of deaths per country, and the number of recovery cases. Conclusion: By comparing the statistical analysis of confirmed cases
vs. deaths within a short period, nCov-19 affected the most compared with Zoonotic viruses. |
|
|
Bhumika |
Gender in Management |
Public Health response| Interventions de santé publique |
This paper aims to attempt to explore the nature of relationship between work–life balance and emotional exhaustion
experienced by the employed individuals while working from home during the pandemic COVID-19 induced nationwide lockdown in the Indian setting. Design/methodology/approach: Data were collected from 180 working professionals in North India who were working
from home during the lockdown. Findings: Findings depicted that in comparison to men, women felt more emotional exhaustion due to personal life interference in work during work from home period. Surprisingly, the relationship between work interference with
personal life, and emotional exhaustion did not differ by gender. It was found that the participative leadership could contribute to reduction of work interference with personal life, and through such an influence, emotional exhaustion experienced by an employee
could be reduced to some extent |
|
|
Biswas, SK, Ghosh, et al |
Nonlinear Dynamics |
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie |
In this work, we have formulated a deterministic compartmental model to study the spreading of COVID-19 and estimated
the model parameters by fitting the model with reported data of ongoing pandemic in India. Sensitivity analysis has been done to identify the influential model parameters. The basic reproduction number has been estimated from actual data and the effective
basic reproduction number has been studied on the basis of reported cases. Some effective preventive measures and their impact have also been studied. Prediction are given on the future trends of the virus transmission under some control measures. Finally,
the positive measures to control the disease have been summarized in the conclusion section. |
|
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Early Psychological Correlates Associated With COVID-19 in A Spanish Older Adult Sample |
Bobes-Bascarán, T, Sáiz, et al |
American Journal of Geriatric Psychiatry |
Public Health response| Interventions de santé publique |
Main aims of the study are to examine the early psychological correlates associated with the COVID-19 pandemic and
lockdown on the mental health of a Spanish older adult sample and to analyze the influence of past mental disorder (PMD) and current mental disorder (CMD) on those correlates. Methods: Cross-sectional study based on an online snowball recruiting questionnaire.
Psychological correlates assessed with the Depression, Anxiety, and Stress Scale (DASS-21) and Impact of Event Scale (IES). Results: There were 342 (15.6%) individuals who reported a PMD and 162 (7.4%) who reported a CMD. Avoidant (32.1%) and depressive (25.6%)
styles were the most prevalent, regardless of mental health status. Main risk factors for negative affectivity were female gender and history CMD or PMD. However, job stability and the ability to enjoy free time were generally associated with better outcomes.
No differences were found in psychological correlates between those with no lifetime history of mental disorder versus PMD on the DASS-21 or IES. |
|
Boixeda, R, Campins, et al |
Revista clinica espanola |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
We have analyzed the prevalence of COPD in patients at our center treated for COVID-19, specifically evaluating their
background treatment with inhalers as potentially protective factors against SARS-CoV-2 infection. A retrospective observational study was carried out at the Mataró hospital, where hospitalized patients with a clinical and / or microbiological diagnosis of
SARS-CoV-2 were identified from March 10 to April 22, 2020. We have compared the background treatment of COPD patients in our COVID-19 cohort with other published series of patients admitted for an exacerbation of COPD in relation to other respiratory pathogens
or in a stable clinical situation. We have not found differences in the use of inhaled corticosteroids between the two groups. However, the use of tiotropium has been significantly lower in COPD patients who have been hospitalized for COVID-19 in relation
to other stable phase COPD cohorts without SARS-CoV-2 infection and controlled in primary care. |
|
|
Borjas, GJ |
Preventing chronic disease |
Epidemiology| Épidémiologie Public health interventions*| Interventions de santé publique |
This study examines how the business closures and activity restrictions affected COVID-19 testing results. METHODS:
Daily data on the fraction of COVID-19 tests yielding a positive result at the zip code level were analyzed in relation to the number of visits to local businesses (based on smartphone location) and the number of smartphones that stayed fixed at their home
location. RESULTS: A large number of visits to local businesses increased the positivity rate of COVID-19 tests, while a large number of smartphones that stayed at home decreased it. A doubling in the relative number of visits increases the positivity rate
by about 12.4 percentage points. A doubling in the relative number of stay-at-home devices lowered it by 2.0 percentage points. The business closures and out-of-home activity restrictions decreased the positivity rate, accounting for approximately 25% of the
decline observed in April and May 2020. |
|
|
Briz-Redón, Á |
arXiv |
Epidemiology| Épidémiologie |
In this paper, a COVID-19 dataset containing the number of daily cases registered in the regions of Catalonia (Spain)
since the start of the pandemic is analysed. Specifically, the possible effect of several environmental variables (solar exposure, mean temperature, and wind speed) on the number of cases is assessed. Thus, the first objective of the paper is to show how the
choice of a certain type of statistical model to conduct the analysis can have a severe impact on the associations that are inferred between the covariates and the response variable. Secondly, it is shown how the use of spatio-temporal models accounting for
the nature of the data allows understanding the evolution of the pandemic in space and time. |
|
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Hypercytokinemia in COVID-19: Tear cytokine profile in hospitalized COVID-19 patients |
Burgos-Blasco, B, Güemes-Villahoz, et al |
Experimental eye research |
Epidemiology| Épidémiologie Clinical data| Données cliniques Immunology | Immunologie |
The aim of this study is to analyze the concentrations of cytokines in tear of hospitalized COVID-19 patients compared
to healthy controls. Tear samples were obtained from 41 healthy controls and 62 COVID-19 patients. Twenty-seven cytokines were assessed. In tear samples of COVID-19 patients, an increase in IL-9, IL-15, G-CSF, GM-CSF, IFN-γ, PDGF and VEGF was observed, along
with a decrease in eotaxin compared to the control group. A poor correlation between IL-6 levels in tear and blood was found. IL-1RA and GM-CSF were significantly lower in severe patients and those who needed treatment targeting the immune system. Tear cytokine
levels corroborate the inflammatory nature of SARS-CoV-2. |
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The effects of COVID-19 lockdown on fairness and cooperation: Evidence from a lablike experiment |
Buso, IM, De Caprariis, et al |
Economics Letters |
Public Health response| Interventions de santé publique |
We run an experiment to study the effects of Covid-19 lockdown in Italy on preferences for fairness and cooperation.
Given the impossibility of having participants in the lab during the lockdown, we adopted an online methodology based on a multi-platform architecture that brings experimental subjects in a “Lab on the Web”. Results from standard Ultimatum and linear Public
Good games show that the circumstances in which participants lived the lockdown significantly affect their behavior in the two games. In particular, participants are more selfish in the ultimatum bargaining and contribute more to the public good when social
isolation is stronger. However, cooperation decreases when lockdown is longer. We interpret these results as evidence of “social embeddedness” to compensate for “social distancing”. |
|
Cai, Y, Shi, et al |
Diabetes research and clinical practice |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
No study elucidated the role of fasting blood glucose (FBG) level in the prognosis of coronavirus disease 2019 (COVID-19).
Methods: This cohort study was conducted in a single center at Renmin Hospital of Wuhan University, Wuhan, China. Clinical laboratory, and treatment data of inpatients with laboratory-confirmed COVID-19 were collected and analyzed. Outcomes of patients with
and without pre-existing diabetes were compared. Results: A total of 941 hospitalized patients with COVID-19 were enrolled in the study. There was a positive relationship between pre-existing diabetes and the mortality of patients who developed COVID-19. FBG
≥7.0 mmol/L was an independent risk factor for the mortality of COVID-19 regardless of the presence or not of a history of diabetes. |
|
|
Cai, Z, Cui, et al |
Journal of psychiatric research |
Healthcare Response | Réponse des soins de santé |
Aims: To assess the magnitude of the psychological status and associated risk factors among nurses in the pandemic
center in Wuhan, China. Methods: In this study, we enrolled nurses from Renmin Hospital of Wuhan University. The questionnaire was designed to obtain basic information of the participants, and included four psychological assessment scales. Results: During
the pandemic, over one-third of nurses suffered from depression, anxiety, and insomnia. In the outbreak period, the nurses showed significantly higher risks for depression, anxiety, and posttraumatic stress disorder (PTSD) symptoms than those in the stable
period. Notably, the nurses from the Fangcang shelter hospitals were more likely to present psychological problems than those from other frontline or non-frontline units, especially for insomnia (38.3% with severe insomnia). |
|
|
Campos, A, Oliveira, et al |
Clinical Ophthalmology |
Healthcare Response | Réponse des soins de santé |
Objective: To describe how a fixed regimen of intravitreal injections (IVI) was helpful to continue activity during
the COVID-19 outbreak and lockdown and to address basic conditions to resume activity. Methods: A fixed regimen of IVI was conceived to significantly reduce the number of visits while keeping a number of injections related to the best outcomes. We retrospectively
collected data of surgeries performed in 2019 and in the first seven months of 2020 and from OCTs in the first semester of 2020. Results: IVI per month, from January to July 2020, were 304, 291, 256, 204, 276, 297 and 322, respectively. OCTs dropped from a
mean of 25.7 per day in the first half of March 2020 to 5.8 per day in the second half of March. A mean of 6.5 OCTs per day was made in April, rising to 19.1 in May and 39.5 in June. Conclusion: It was possible to keep the ophthalmological activity during
the pandemic outbreak due to the existence of a pre-scheduled fixed regimen for IVI and to the availability of personal protective equipment. |
|
|
Canals, M, Cuadrado, et al |
Revista Panamericana de Salud Publica/Pan American Journal of Public Health |
Epidemiology| Épidémiologie Public health interventions*| Interventions de santé publique |
Objectives. To report the surveillance of COVID-19 pandemic in Chile and analyse the response to public health interventions
implemented from 3 March to 30 June 2020 and to assess the risks of collapse of the health care system. Methods. We analysed the effective reproductive number, underreporting of cases, burden of critical beds, case fatality ratio and number of diagnostic RT-PCR
for SARS-CoV-2. Results. After an accelerated onset, the COVID-19 pandemic seemed to be relatively controlled in Chile (late April 2020), with reproductive numbers close to 1.00. However, at this time, the load of infected patients was high, with an important
number of underreported cases; the diagnostic effort was still limited and heterogeneous across regions. After 1 May up to 30 June a marked exponential increase in the number of cases was observed with a peak on June 14. Our findings suggest that the implemented
public health interventions have been initially effective in decreasing the spread of the pandemic. Premature decisions to relax these interventions may have resulted in a rebound in cases with a rapid saturation of the health care system. |
|
|
Canetta, C, Accordino, et al |
Autonomic Neuroscience: Basic and Clinical |
Clinical data| Données cliniques |
We describe clinical and laboratory findings in 35 patients tested positive for SARS-CoV-2 by reverse transcriptase-polymerase
chain reaction on nasopharyngeal swab experiencing one or multiple syncope at disease onset. |
|
|
Cao, Xia, Maruyama, et al |
bioRxiv |
Coronavirology| Coronavirologie Immunology | Immunologie |
We report here on the use of a naive phage display antibody library to identify a panel of fully human SARS-CoV-2 neutralizing
antibodies. Following functional profiling in vitro against an early pandemic isolate as well as a recently emerged isolate bearing the D614G Spike mutation, the clinical candidate antibody, STI-1499, and the affinity-engineered variant, STI-2020, were evaluated
for in vivo efficacy in the Syrian golden hamster model of COVID-19. Both antibodies demonstrated potent protection against the pathogenic effects of the disease and a dose-dependent reduction of virus load in the lungs, reaching undetectable levels following
a single dose of 500 micrograms of STI-2020. |
|
|
Capuzzi, E, Di Brita, et al |
Psychiatry research |
Public Health response| Interventions de santé publique Healthcare Response | Réponse
des soins de santé |
Objective: We aimed to compare the number and characteristics of emergency psychiatric consultations during the phase
1 of lockdown with respect to the same period in 2019 in a Department of Mental Health and Addiction (DMHA) located in Lombardy region. Methods: We conducted a cross-sectional study including subjects consecutively admitted to two psychiatric emergency rooms
of DMHA in Monza, Lombardy, Italy. Results: Between February 21st and May 3rd 2020, there was a marked reduction in the number of psychiatric emergency consultations, if compared to the same period of 2019. Subjects who were living in psychiatric residential
treatment facilities, had cannabis addiction and a diagnosis of obsessive-compulsive disorder were significantly more likely to present to emergency psychiatric consultations during lockdown. |
|
|
Caracciolo, M, Macheda, et al |
Frontiers in Immunology |
Clinical data| Données cliniques |
Case report of an 85 year old male presenting in our hospital with COVID-19, whose condition was complicated by acute
respiratory distress syndrome and cardiac and renal failure. |
|
|
32397692; A case of COVID-19 infection manifesting
with only abdominal symptoms |
Caranti, A, Budini, et al |
Minerva chirurgica |
Clinical data| Données cliniques |
Authors present a case of a 72-year-old patient admitted to their Emergency Room department with a 1-week history of
inappetence and abdominal pain. It is important to notice how clinicians could neglect the suspect of a COVID-19 infection in such patients. |
|
Can Psychological Traits Explain Mobility Behavior During the COVID-19 Pandemic? |
Chan, HF, Moon, et al |
Social Psychological and Personality Science |
Public Health response| Interventions de santé publique |
The authors conducted 2 studies to evaluate the effect of psychological traits on compliance with mobility restrictions.
They found significant effects on reasons for leaving home, as well as age and gender differences, particularly relating to female agreeableness for previous and future social mobility behaviors. |
|
A Post-Infectious Steroid-Responsive Brainstem Lesion Associated With COVID-19 |
Chang, P, Tasch, et al |
Neurohospitalist |
Clinical data| Données cliniques |
A 51-year-old man developed coma, bilateral pupillary dilation, ophthalmoplegia and quadriplegia 4 weeks after testing
positive for COVID-19. MRI demonstrated a symmetric midline pontine non-enhancing T2-FLAIR hyperintense lesion. The patient was treated with intravenous methylprednisolone, which resulted in improvement of his Glasgow Coma Scale (GCS) from 3 to 15 over the
next 5 days. To our knowledge, this is the first case of a post-infectious steroid-responsive brainstem lesion associated with COVID-19. The clinical picture best fits in the family of a steroid-responsive encephalopathy and reminds us that COVID-19 may cause
severe post-infectious neurological complications. © The Author(s) 2020. |
|
Chaudhary, FA, Ahmad, et al |
Journal of occupational health |
Healthcare Response | Réponse des soins de santé |
The aim of the study was to evaluate the oral healthcare workers' (OHCW) concerns, perceived impact, and preparedness
in COVID-19 pandemic. The majority of OHCW felt concerned about their risk of exposure to infection and falling ill from exposure and infecting friends/family. |
|
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SARS-CoV-2 pandemic and epilepsy: The impact on emergency department attendances for seizures |
Cheli, M, Dinoto, et al |
Seizure |
Healthcare Response | Réponse des soins de santé |
Authors performed a retrospective study to evaluate the issues the risk of acquiring SARS-CoV-2 in a hospital setting
and the need of reorganizing the Emergency Departments (EDs) to cope with infected patients which have led to a reduction of ED attendances for non-infectious acute conditions and to a different management of chronic disorders. Data suggest that the pandemic
has affected the way patients with seizures access the Health Care System. |
|
Chen, C, Wang, et al |
Journal of International Medical Research |
Clinical data| Données cliniques |
The objective of this study was to evaluate temporal lung changes in COVID-19 in high-resolution computed tomography
(HRCT) and to determine the appropriate computed tomographic (CT) follow-up time. The appropriate follow-up time of CT scans is during the second week and the fourth to fifth weeks from the onset of illness. |
|
|
Characteristics of eight pediatric patients with coronavirus disease 2019 |
Chen, G, Li, et al |
Iranian Journal of Pediatrics |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
Authors retrospectively analyzed the epidemiological, laboratory, imaging, and clinical data of pediatric patients
with COVID-19. Pediatric patients with COVID-19 were mainly transfected through family cluster outbreaks. |
|
Chen, Q, Yang, et al |
Frontiers in Medicine |
Healthcare Response | Réponse des soins de santé |
Here, we have reported an urgent ERCP in a patient with acute pancreatitis secondary to JPDD-related biliary stone.
Based on our experiences, the objective is to provide practical suggestions for the safe resumption of ERCP procedures in the setting of the COVID-19 pandemic with specific focus on patient risk assessment, personal protection equipment (PPE), and dress code
modalities, all of which have been implemented in our hospital to reduce the risk of viral transmission. |
|
|
Chen, SLS, Yen, et al |
Journal of medical Internet research |
Epidemiology| Épidémiologie Public health interventions*| Interventions de santé publique |
In this study a simple LSD index was developed for health decision makers to do real-time assessment of COVID-19 at
the global, country, region, and community level. After large-scale outbreaks in a few countries before mid-March, the global weekly LSD index peaked at 4.27 in March and lasted until mid-June (pandemic phase), during which most countries were affected and
needed to take various social distancing measures. |
|
|
Chen, X, Yin, et al |
International Journal of Medical Sciences |
Therapeutics| Thérapeutique |
ShuFeng JieDu capsule (SFJDC), a traditional Chinese medicine, has been recommended for the treatment of COVID-19 infections.
However, the pharmacological mechanism of SFJDC still remains vague to date. The active ingredients and their target genes of SFJDC were collected from TCMSP. COVID-19 is a type of Novel Coronavirus Pneumonia (NCP). NCP-related target genes were collected
from GeneCards database. The ingredients-targets network of SFJDC and PPI networks were constructed. The candidate genes were screened by Venn diagram package for enrichment analysis. The gene-pathway network was structured to obtain key target genes. In total,
124 active ingredients, 120 target genes of SFJDC and 251 NCP-related target genes were collected. The functional annotations cluster 1 of 23 candidate genes (CGs) were related to lung and Virus infection. RELA, MAPK1, MAPK14, CASP3, CASP8 and IL6 were the
key target genes. The results suggested that SFJDC cloud be treated COVID-19 by multi-compounds and multi-pathways, and this study showed that the mechanism of traditional Chinese medicine (TCM) in the treatment of disease from the overall perspective. © The
author(s). |
|
|
Chen, Y, Shi, et al |
Biosensors and Bioelectronics |
Diagnostics / Pathogen detection| Diagnostics / Détection d'agents pathogènes |
Authors reported a contamination-free visual detection method for SARS-CoV-2 with LAMP and CRISPR/Cas12a technology.
For 7 positive and 3 negative respiratory swab samples provided by Zhejiang Provincial Center for Disease Control and Prevention, our detection results had 100% positive agreement and 100% negative agreement, which demonstrated the accuracy and application
prospect of this method. |
|
|
Cheng, LL, Guan, et al |
JAMA Internal Medicine |
Clinical data| Données cliniques Therapeutics| Thérapeutique RCT |
The objective of this study was to determine whether a therapy that increases peripheral blood leukocyte and lymphocyte
cell counts leads to clinical improvement in patients with COVID-19. In preliminary findings from a randomized clinical trial, rhG-CSF treatment for patients with COVID-19 with lymphopenia but no comorbidities did not accelerate clinical improvement, but the
number of patients developing critical illness or dying may have been reduced. |
|
|
Chhetri, A, Chettri, et al |
Journal of Molecular Structure |
Coronavirology| Coronavirologie |
A series of six novel imidazole anchored azo-imidazole derivatives (L1-L6) have been prepared by the simple condensation
reaction of azo-coupled ortho-vaniline precursor with amino functionalised imidazole derivative and the synthesized derivatives (L1-L6) have been characterized by different analytical and spectroscopic techniques. Molecular docking studies were carried out
to ascertain the inhibitory action of studied ligands (L1-L6) against the Main Protease (6LU7) of novel coronavirus (COVID-19). The result of the docking of L1-L6 showed a significant inhibitory action against the Main protease (Mpro) of SARS-CoV-2 and the
binding energy (ΔG) values of the ligands (L1-L6) against the protein 6LU7 have found to be -7.7 Kcal/mole (L1), -7.4 Kcal/mole (L2), -6.7 Kcal/mole (L3), -7.9 Kcal/mole (L4), -8.1 Kcal/mole (L5) and -7.9 Kcal/mole (L6). Pharmacokinetic properties (ADME) of
the ligands (L1-L6) have also been studied. © 2020 Elsevier B.V. |
|
|
Characterization of Covid-19 Dataset using Complex Networks and Image Processing |
Chire, Josimar, Zuniga, et al |
arXiv |
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection
d'agents pathogènes |
This paper aims to explore the structure of pattern behind covid-19 dataset. The dataset includes medical images with
positive and negative cases. A sample of 100 sample is chosen, 50 per each class. An histogram frequency is calculated to get features using statistical measurements, besides a feature extraction using Grey Level Co-Occurrence Matrix (GLCM). Using both features
are build Complex Networks respectively to analyze the adjacency matrices and check the presence of patterns. Initial experiments introduces the evidence of hidden patterns in the dataset for each class, which are visible using Complex Networks representation. |
|
Ciepłucha, H, Knysz, et al |
Postepy higieny i medycyny doswiadczalnej |
Clinical data| Données cliniques |
This article presents the case of a 47-year-old woman with SARS-CoV-2 infection. Due to persistent symptoms of infection,
therapy containing chloroquine and azithromycin was introduced, obtaining a very quick improvement in the condition of the infected patient. The current positions of the World Health Organization (WHO) and the Food and Drug Administration (FDA) in terms of
the topic were also presented. |
|
|
Evolutionary multi-objective design of sars-cov-2 protease inhibitor candidates |
Cofala, T, Elend, et al |
|
Coronavirology| Coronavirologie Therapeutics| Thérapeutique |
Computational drug design based on artificial intelligence is an emerging research area. At the time of writing this
paper, the world suffers from an outbreak of the coronavirus SARS-CoV-2. A promising way to stop the virus replication is via protease inhibition. We propose an evolutionary multi-objective algorithm (EMOA) to design potential protease inhibitors for SARS-CoV-2
’s main protease. Based on the SELFIES representation the EMOA maximizes the binding of candidate ligands to the protein using the docking tool QuickVina 2, while at the same time taking into account further objectives like drug-likeness or the fulfillment
of filter constraints. The experimental part analyzes the evolutionary process and discusses the inhibitor candidates. © Springer Nature Switzerland AG 2020. |
|
Cook, LL, Zschomler, et al |
Journal of Children's Services |
Healthcare Response | Réponse des soins de santé |
This study aims to examine the extent to which social work teams can function as a secure base in the context of remote
working. In this study, the authors report findings in three key areas: how social workers experienced the sudden shift to increased remote working; how social work teams provided a secure base for remote working; and the challenges for sustaining the team
as a secure base when working remotely. |
|
|
The impacts of COVID-19 crisis over the tourism expectations of the Azores Archipelago residents |
Couto, G, Castanho, et al |
Sustainability (Switzerland) |
Public Health response| Interventions de santé publique |
This article intends to identify the Azores Archipelago residents' tourism expectations during the COVID-19 crisis.
This study shows that majority of the respondents (61.6%) would not make a reservation for a 2020 vacation. |
|
Cruickshank, IJ, Carley, et al |
Applied Network Science |
Public Health response| Interventions de santé publique |
In this study, authors propose analyzing discussion topics on Twitter by clustering hashtags. They find that some topical
clusters of hashtags shift over the course of the pandemic, while others are persistent throughout, and that there are distinct temporal trends in hashtag usage. |
|
|
Depression reported by US adults in 2017–2018 and March and April 2020 |
Daly, M, Sutin, et al |
Journal of affective disorders |
Public Health response| Interventions de santé publique |
In this study, authors aimed to assess depression levels before and during the COVID-19 pandemic in the United States.
Findings suggest that depression levels have risen substantially during the COVID-19 pandemic and reinforce recent findings indicating that young adults may be particularly vulnerable to the mental health effects of the pandemic. |
|
32944509; Evidence of COVID-19 Impacts on Occupations During the First Vietnamese National Lockdown |
Dang, AK, Le, et al |
Annals of global health |
Public Health response| Interventions de santé publique |
This study aimed to identify negative impacts of COVID-19 on occupations of Vietnamese people during the first national
lockdown, including the quality and quantity of jobs as well as adverse problems at work due to COVID-19. The study revealed a drastic reduction in both the quality and quantity of working, as well as the increased fear and stigmatization of exposure to COVID-19
at workplaces. |
|
Dávila Serrano, EE, Dhelft, et al |
|
Healthcare Response | Réponse des soins de santé |
Acute respiratory distress syndrome (ARDS) is a critical impairment of the lung function, which occurs – among others
– in severe cases of patients with Covid-19. Its therapeutic management is based on mechanical ventilation, but this may aggravate the patient’s condition if the settings are not adapted to the actual lung state. Computed tomography images allow for assessing
the lung ventilation with fine spatial resolution, but their quantitative analysis is hampered by the contrast loss due to the disease. This article describes software developed to assist the clinicians in this analysis by implementing semi-automatic algorithms
as well as interactive tools. The focus is the assessment of the cyclic hyperinflation, which may lead to ventilator-induced lung injury. For this purpose aerated parts of the lungs were segmented in twenty ARDS patients, half with Covid-19. The results were
in very good agreement with manual segmentation performed by experts: (5.1 ml) mean difference in measured cyclic hyperinflation. © 2020, Springer Nature Switzerland AG. |
|
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De la Hoz-Restrepo, F, Alvis-Zakzuk, et al |
International Journal of Infectious Diseases |
Epidemiology| Épidémiologie Surveillance |
This paper presents a critical analysis of the Colombian surveillance data in order to identify strengths and pitfalls
of the control measures. A descriptive analysis of PCR-confirmed cases between March and July 25 was performed. By July 25, Colombia (population 50 372 424) had reported 240 745 cases and 8269 deaths (case fatality rate of 3.4%). A total of 1 370 271 samples
had been analyzed (27 405 samples per million people), with a positivity rate of 17%. Sampling rates per million varied by region from 2664 to 158 681 per million, and consequently the incidence and mortality rates also varied. Due to geographical variations
in surveillance capacity, Colombia may have overlooked up to 82% of the actual cases. |
|
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32918938; Unusual arterial thrombotic events in Covid-19 patients |
de Roquetaillade, C, Chousterman, et al |
International journal of cardiology |
Clinical data| Données cliniques |
This study aimed to describe the clinical and biological characteristics of COVID-19 patients presenting with an associated
arterial thromboembolic event. We performed a retrospective multicentric study in 3 centers between France and Italy. From March 8th to April 25th 2020, we identified 20 patients (24 events) with arterial thromboembolic events over 209 admitted patients (9.6%)
with severe COVID-19 infection. Arterial thrombotic events included acute coronary occlusions (n = 9), stroke (n = 6), limb ischemia (n = 3), splenic infarcts (n = 3), aortic thrombosis (n = 2) and occlusive mesenteric ischemia (n = 1). At the time of the
event, 10/20 (50%) of patients received thromboprohylaxis, 2/20 (10%) were receiving treatment dose anticoagulation and 5/20 (25%) were receiving antiplatelet therapy. |
|
COVID-19 Infection Map Generation and Detection from Chest X-Ray Images |
Degerli, Aysen, Ahishali, et al |
arXiv |
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection
d'agents pathogènes |
This study proposes a novel method for the joint localization, severity grading, and detection of COVID-19 from CXR
images by generating the so-called infection maps that can accurately localize and grade the severity of COVID-19 infection. To accomplish this, we have compiled the largest COVID-19 dataset up to date with 2951 COVID-19 CXR images, where the annotation of
the ground-truth segmentation masks is performed on CXRs by a novel collaborative expert human-machine approach. A detailed set of experiments show that state-of-the-art segmentation networks can learn to localize COVID-19 infection with an F1-score of 85.81%,
that is significantly superior to the activation maps created by the previous methods. Finally, the proposed approach achieved a COVID-19 detection performance with 98.37% sensitivity and 99.16% specificity. |
|
Frailty and SARS-CoV-2 infection. A population-based study in a highly endemic village |
Del Brutto, OH, Costa, et al |
Journal of the neurological sciences |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
This research is studying whether or not frail subjects are more prone to acquire SARS-CoV-2 infection in endemic communities,
independently of risk factors inherent to aging or other comorbidities. This study uses a well-established and ongoing population-based cohort study designed to assess factors influencing the burden of neurological and cardiovascular diseases in rural Ecuador.
Findings show that frailty does not predispose to SARS-CoV-2 infection in community-dwelling older adults. |
|
Delorme, C, Paccoud, et al |
European Journal of Neurology |
Clinical data| Données cliniques |
This article reports four cases of COVID-19-related encephalopathy. The diagnosis was made in patients with confirmed
COVID-19 who presented with new-onset cognitive disturbances, central focal neurological signs, or seizures. All patients underwent cognitive screening, brain magnetic resonance imaging (MRI), lumbar puncture, and brain 2-desoxy-2-fluoro-D-glucose (FDG)-positron-emission
tomography (PET)/computed tomography (CT) (FDG-PET/CT). Despite varied clinical presentations, all patients presented with a consistent FDG-PET pattern, which may reflect an immune mechanism. |
|
|
Predicting clinical re-admission using discharge summaries (pcruds) |
Dhanalakshmi, TS, Meleet, et al |
|
Healthcare Response | Réponse des soins de santé |
Article discussing the use of electronic medical records and natural language processing to help predict hospital re-admission. |
|
Ding, D, Guan, et al |
Frontiers of Business Research in China |
Economics | Économie |
This paper aims to investigate the sectors that have performed better even as market sentiment is affected by the pandemic.
The daily closing stock prices of a total usable sample of 1,567 firms from 37 sectors are first analyzed using a combination of hierarchical clustering and shape-based distance (SBD) measures. Market sentiment is modeled from Google Trends on the COVID-19
pandemic. This is then analyzed against the time series of daily closing stock prices using augmented vector autoregression (VAR). The empirical results indicate that market sentiment towards the pandemic has significant effects on the stock prices of the
sectors. Particularly, the stock price performance across sectors is differentiated by the level of the digital transformation of sectors, with those that are most digitally transformed, showing resilience towards negative market sentiment on the pandemic. |
|
|
Factors associated with burnout among physicians: An evaluation during a period of COVID-19 pandemic |
Dinibutun, SR |
Journal of Healthcare Leadership |
Healthcare Response | Réponse des soins de santé |
The aim of the study is to evaluate the prevalence and extent of burnout among physicians and investigate the factors
related with burnout and the influence of the fight against coronavirus (COVID-19) on the burnout syndrome. Methods: A cross-sectional survey design was adopted and conducted on 200 actively working physicians in Izmir/Turkey. One important finding showed
that the burnout level of physicians who actively involved in the fight against COVID-19 was lower than the burnout level of the physicians who did not actively involve in the fight against COVID-19. |
|
Proximity Inference with Wifi-Colocation during the COVID-19 Pandemic |
Dmitrienko, Mikhail, Singh, et al |
arXiv |
Public health interventions*| Interventions de santé publique |
In this work we propose using WiFi signals recorded on the phone for performing digital contact tracing. The approach
works by scanning the access point information on the device and storing it for future purposes of privacy preserving digital contact tracing. We make our approach resilient to different practical scenarios by configuring a device to turn into hotspot if the
access points are unavailable. This makes our proposed approach to be feasible in both dense urban areas as well as sparse rural places. We compare and discuss various shortcomings and advantages of this work over other conventional ways of doing digital contact
tracing. Preliminaries results indicate the feasibility and efficacy of our approach for the task of proximity sensing which could be relevant and accurate for its relevance to contact tracing and exposure notifications. |
|
Dolan, Hugo, Rastelli, et al |
arXiv |
Modelling/ prediction| Modélisation/prédiction Transmission |
We study how international flights can facilitate the spread of an epidemic to a worldwide scale. We combine an infrastructure
network of flight connections with a population density dataset to derive the mobility network, and then define an epidemic framework to model the spread of disease. Our approach combines a compartmental SEIRS model with a graph diffusion model to capture
the clusteredness of the distribution of the population. The resulting model is characterised by the dynamics of a metapopulation SEIRS, with amplification or reduction of the infection rate which is determined by the mobility of individuals. Then, we use
simulations to characterise and study a variety of realistic scenarios that resemble the recent spread of COVID-19. Crucially, we define a formal framework that can be used to design epidemic mitigation strategies: we propose an optimisation approach based
on genetic algorithms that can be used to identify an optimal airport closure strategy, and that can be employed to aid decision making for the mitigation of the epidemic, in a timely manner. |
|
|
Case series: Failure of imaging & biochemical markers to capture disease progression in COVID-19 |
Dorey-Stein, Z, Myers, et al |
Respiratory Medicine Case Reports |
Clinical data| Données cliniques Healthcare Response | Réponse des soins de santé |
We report four individuals admitted for acute respiratory failure due to COVID-19 who demonstrated significant clinical
improvement prior to discharge and subsequently were readmitted with worsening respiratory failure, elevated inflammatory markers and worsening chest imaging. We propose a multi-disciplinary discharge criterion to establish a safer discharge process including
trending inflammatory markers, daily imaging and pursuing follow up CT chest, particularly in individuals with significant morbidities and health disparities. © 2020 The Authors |
|
32918975; Parameters predicting COVID-19-induced myocardial injury and mortality |
Duerr, GD, Heine, et al |
Life Sciences |
Clinical data| Données cliniques |
Objective: To elucidate prognostic markers to identify patients at risk. Results: Only patients with pericardial effusion
(PE) developed a severe disease course, and those who died could be identified by a high CD8/Treg/monocyte ratio. Conclusions: PE predicts cardiac injury in COVID-19 patients. Therefore, TTE should be performed at admission. Immunological parameters for dysfunctional
antiviral immunity, such as the CD8/Treg/monocyte ratio used here, supports risk assessment by predicting poor prognosis. |
|
Biomarkers for the prediction of venous thromboembolism in critically ill COVID-19 patients |
Dujardin, RWG, Hilderink, et al |
Thrombosis research |
Clinical data| Données cliniques Healthcare Response | Réponse des soins de santé |
Objective: To develop a prediction model for VTE in critically ill COVID-19 patients. Patients and methods: In this
retrospective cohort study, 127 adult patients with confirmed COVID-19 infection admitted to the intensive care unit of two teaching hospitals in the Netherlands were included. VTE was diagnosed with either ultrasound or computed tomography scan. Univariate
receiver operating characteristic (ROC) curves were constructed for various hypoxemia, inflammation and coagulation biomarkers. Multivariate analysis was done using binary linear regression. Results: Variables associated with VTE in both univariate and multivariate
analysis were D-dimer and CRP. Variables indicating hypoxemia were not predictive. Authors developed a prediction table with these biomarkers that can aid clinicians in the timing of imaging in patients with suspected VTE. |
|
‘The Bat Soup Myth’: An Evaluation on Contemporary Myths and Urban Legends about
Coronavirus |
Duman, M |
Milli Folklor |
Public Health response| Interventions de santé publique |
In this study, myths, urban legends, rumors, and fake news about SARS-CoV-2 are evaluated in terms of the motivating
factor and other reasons behind the creation and emergence of the reports, the effective factors in the process of the spread of reports, and the general characteristics and functions of the reports. The main purpose of this essay is to try to determine the
origin of the urban legends about Coronavirus. Another purpose, is to discuss the reasons why these legends spread and gained awareness in a very short time. |
|
Dunkerley, S, Kurar, et al |
Injury |
Healthcare Response | Réponse des soins de santé |
At Great Western Hospital, Swindon, a closed loop audit was performed looking at a selection of these guidelines, to
assess if our initial changes were sufficient and what could be improved. Method: An audit was designed around fracture immobilisation, type of initial fracture clinic assessment, default virtual follow up clinic and late imaging. Interventions were implemented
and re-audited. Conclusion: Virtual fracture clinics, both triaging new patients and follow-up clinics have dramatically changed our outpatient management, helping the most appropriate patients to be seen face to face. Despite their limitations, they have
been well tolerated by patients and improved patient safety and treatment. |
|
|
Emergency surgery in COVID-19 outbreak: Has anything changed? Single center experience |
D'Urbano, F, Fabbri, et al |
World Journal of Clinical Cases |
Healthcare Response | Réponse des soins de santé |
Authors discuss the surgical activities at the General Surgery Department of Sant'Anna University Hospital in Ferrara,
Italy, during COVID-19. There was a significant reduction in emergency surgeries at our center during the COVID-19 pandemic, and it is plausible that there were analogous reductions at other centers across Italy. |
|
Trend change of the transmission route of COVID-19–related symptoms in Japan |
Eguchi, A, Yoneoka, et al |
Public health |
Epidemiology| Épidémiologie Transmission |
We examined the change of the infection route by investigating contact experiences with COVID-19–positive cases. This
study is a population-level questionnaire-based study using a social networking service (SNS). The results of this study show that the declaration prevented infections in the workplace, but increased domestic infections as people stayed at home. However,
after April 24, workplace infections started to increase again, driven by the increase in community-acquired infections. While careful interpretation is necessary because our data are self-reported from voluntary SNS users, these findings indicate the impact
of the declaration on the change in transmission routes of COVID-19 over time in Japan. |
|
Epidemiology and Clinical Features of Coronavirus Disease 2019 in Moroccan Children |
El Fakiri, K, Nassih, et al |
Indian pediatrics |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
Objectives: This study aims to analyze the epidemiological and clinical features of Coronavirus disease 19 (COVID-19)
in a Moroccan pediatric population. Methods: A retrospective study of a cohort of 74 children with RT-PCR confirmed COVID-19. We collected information on clinical and laboratory features of all children (age <18 years) admitted between 2 March, 2020 and 1
April, 2020. Results: The mean (SD) age of the 74 children (40 girls) was 7 (1.5) years. The mean (SD) time from illness onset to diagnosis was 2 (1) days. 54 children were asymptomatic, while eight had fever, and five cases had cough. Recovery was after a
mean (SD) of 12 (1) days. Conclusions: COVID-19 was mostly mild in the pediatric population in Morocco. © 2020, Indian Academy of Pediatrics. |
|
Erquicia, J, Valls, et al |
Medicina clinica |
Healthcare Response | Réponse des soins de santé |
The aim of the present study was to analyze the emotional status among the health care workers form the Hospital of
Igualada (Barcelona), while they were facing with Covid-19 in one of the most affected regions in all of Europe. A total of 395 participants were included in the study. A significant proportion of professionals reported symptoms of anxiety (31.4%) and depression
(12.2%) from moderate to severe intensity. Symptoms of acute stress were reported by 14.5% of participants. We performed a regression analysis, which explained the 30% of the variance associated with the degree of emotional distress (Ry = 0.30). The final
model reveals that females (or young males), who are working in the frontline as nursing assistants, caretakers or radiology technicians, with the uncertainty of a possible infection, the perception of inadequate protection measures and having experienced
the death of a close person by Covid-19, showed a heightened risk of experiencing psychological distress. |
|
|
32815213; Coronavirus Disease 2019 and Parkinsonism: A Non-post-encephalitic Case |
Faber, I, Brandão, et al |
Movement Disorders |
Clinical data| Données cliniques |
Report of a COVID-19 case who developed akinetic‐rigid parkinsonism. As the patient was neurologically normal prior
to the COVID‐19 infection, authors conclude that SARS‐CoV‐2 infection is responsible for the parkinsonism. |
|
Spontaneous pneumothorax as a complication in COVID-19 male patient: A case report |
Fahad, AM, Mohammad, et al |
Clinical Case Reports |
Clinical data| Données cliniques |
Coronavirus disease 2019 infection may be later complicated with pneumothorax after primarily symptoms. We must be
aware about pneumothorax, which may be increased in cases of COVID-19. © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd |
|
Fan, BB, Yang, et al |
|
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection
d'agents pathogènes |
Coronary Virus Disease 2019 swept the world and caused serious impact on human society. Doctors usually use CT scan
pictures and chest X-ray images to determine whether a patient is infected. Many researchers try to use deep learning methods to test COVID-19 of patients. However, there are many problems when using deep learning methods for feature extraction, such as: fewer
data samples, unclear pictures, and pictures containing special marks. This article uses deep learning methods for COVID-19 detection and visual analysis of popular deep learning methods. Experiments verify that when using deep learning in the public small
sample COVID-19 dataset, a small part of the test results are not reliable. We propose solutions to the problems of deep learning during COVID-19 detection. © 2020 Institute of Physics Publishing. All rights reserved. |
|
|
Xerostomia, gustatory and olfactory dysfunctions in patients with COVID-19 |
Fantozzi, PJ, Pampena, et al |
American Journal of Otolaryngology - Head and Neck Medicine and Surgery |
Clinical data| Données cliniques |
This study aimed to evaluate the prevalence and characterize specific symptoms associated with COVID-19. Methods: This
retrospective study included 326 patients with confirmed SARS-CoV-2 infection evaluated at the Emergency Department of the Umberto I Polyclinic Hospital, Rome, Italy between March 6th and April 30th, 2020. In order to assess xerostomia, olfactory and gustatory
dysfunctions secondary to COVID-19, a telephone-based a modified survey for taste and smell disorders and the Fox Questionnaire for dry mouth were administered to 111 patients (34%) after discharge between June 4th and June 12th. Results indicate that xerostomia,
gustatory and olfactory dysfunctions may present as a prodromal or as the sole manifestation of COVID-19. |
|
Fazzini, M, Baresi, et al |
International Journal of Environmental Research and Public Health |
Epidemiology| Épidémiologie |
The goal of this study is to individuate relationships between several climate parameters (temperature, relative humidity,
accumulated precipitation, solar radiation, evaporation, and wind direction and intensity), local morphological parameters, and new daily positive swabs for COVID-19, which represents the only parameter that can be statistically used to quantify the pandemic.
Daily data on meteorological conditions and new cases of COVID-19 were collected for the Lombardy Region (Northern Italy) from 1 March, 2020 to 20 April, 2020. This region exhibited the largest rate of official deaths in the world, with a value of approximately
1700 per million on 30 June 2020. Moreover, the apparent lethality was approximately 17% in this area, mainly due to the considerable housing density and the extensive presence of industrial and craft areas. Both the Mann–Kendall test and multivariate statistical
analysis showed that none of the considered climatic variables exhibited statistically significant relationships with the epidemiological evolution of COVID-19, at least during spring months in temperate subcontinental climate areas, with the exception of
solar radiation, which was directly related and showed an otherwise low explained variability of approximately 20%. Furthermore, the average temperatures of two highly representative meteorological stations of Molise and Lucania (Southern Italy), the most
weakly affected by the pandemic, were approximately 1.5 °C lower than those in Bergamo and Brescia (Lombardy), again confirming that a significant relationship between the increase in temperature and decrease in virulence from COVID-19 is not evident, at least
in Italy. |
|
|
ANALYSIS of A REACTION-DIFFUSION EPIDEMIC MODEL with ASYMPTOMATIC TRANSMISSION |
Fitzgibbon, WE, Morgan, et al |
Journal of Biological Systems |
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie |
We develop a dynamic model of an evolving epidemic in a spatially inhomogeneous environment. We analyze the model,
as a system of reaction–diffusion partial differential equations, to predict the outbreak and spatio-temporal spread of the disease. The model features both an asymptomatic infectious stage and symptomatic infectious stage, with both the asymptomatic and the
symptomatic infected populations dispersing through the susceptible population. We prove the existence and uniform boundedness of solutions, and investigate their long-time behavior. We apply the spatially homogeneous version of the model to the current COVID-19
epidemic in Brazil. |
|
Flinck, H, Rauhio, et al |
Diagnostic microbiology and infectious disease |
Diagnostics / Pathogen detection| Diagnostics / Détection d'agents pathogènes |
We compared the performance of the Elecsys® Anti–SARS-CoV-2 and LIAISON® SARS-CoV-2 S1/S2 IgG tests. The seroconversion
panel comprised of 120 samples from 13 hospitalized COVID-19 patients. Based on our results, the SARS-CoV-2 antibodies can be quite reliably detected 2 weeks after NAAT positivity and 3 weeks after the symptom onset with both tests. However, since some COVID-19
patients were positive only with Elecsys®, the antibodies should be screened against N-antigen (Elecsys®) and reactive samples confirmed with S antigen (LIAISON®), but both results should be reported. In some COVID-19 patients, the serology can remain negative. |
|
|
The impact of COVID-19 on the gender division of childcare work in Hungary |
Fodor, É, Gregor, et al |
European Societies |
Public Health response| Interventions de santé publique |
we conducted a representative survey in Hungary to find out how the pandemic affected the gendered division of these
childcare duties. We found that on average, in relative terms, men have increased their contributions at roughly the same rate (by 35 percent) as women. But given that women had been doing a lot more childcare work before the pandemic, in absolute terms, women’s
contributions grew significantly more than men’s and the gap between men and women has increased in absolute work hour terms. This was particularly so among a specific group of women: middle class, highly educated city-dwellers. Our data suggest that in Hungary
the pandemic increased gender inequality the most among the highest educated. |
|
Fu, W, Liu, et al |
EClinicalMedicine |
Clinical data| Données cliniques Therapeutics| Thérapeutique RCT |
In this open-label randomized trial, we found that aerosol inhalation of IFN-κ plus TFF2 in combination with standard
care is safe and superior to standard care alone in shortening the time up to viral RNA negative conversion in all clinical samples. In addition, the patients in experimental group had a significantly shortened CT imaging improvement time than those in control
group. This study suggested that this combination treatment is able to facilitate clinical improvement (negative for virus, improvement by CT, reduced hospitalization stay) and thereby result in an early release from the hospital. These data support the need
for exploration with a large-scale trial of IFN-κ plus TFF2 to treat COVID-19. |
|
|
Fuglebjerg, NJU, Eriksson, et al |
Ugeskrift for laeger |
Clinical data| Données cliniques |
We report a case of multiple peripheral pulmonary thromboembolisms in a 69-year-old male hospitalised due to SARS-CoV-2
infection. There were no evident risk factors for pulmonary thromboembolism, the patient had a Wells' score of zero, and the diagnosis only became evident after repeated CT pulmonary angiographies. |
|
|
On the Usage of Smart Speakers during the Covid-19 Coronavirus Lockdown |
Furini, M, Mirri, et al |
|
Public Health response| Interventions de santé publique |
In this paper we focus on the emerging technology of smart speakers (e.g., Amazon Echo Plus, Google Home, etc.) and,
through a developed questionnaire, we investigate how people use these devices. In particular, we analyze whether the human behavior has been affected by availability of these smart speaker. Results showed that the usage of these devices did not increase during
lockdown, but it highlighted the presence of some privacy issues that might represent a burden to the diffusion of this type of technology. |
|
32781200; SARS-CoV-2 infection: advocacy for training and social distancing in healthcare settings |
Gagneux-Brunon, A, Pelissier, et al |
Journal of Hospital Infection |
Epidemiology| Épidémiologie Healthcare Response | Réponse des soins de santé |
This article reports the observed rate of infection with severe acute respiratory syndrome coronavirus-2 in healthcare
workers (HCWs) who worked on wards dedicated to care of patients with coronavirus disease 2019 (COVID-19) compared with HCWs who worked on non-COVID-19 wards. The infection rate was significantly higher among HCWs who worked on non-COVID-19 wards (odds ratio
2.3, P=0.005), illustrating the need to strengthen social distancing measures and training. |
|
Gangopadhyay, KK, Sinha, et al |
Diabetes & metabolic syndrome |
Healthcare Response | Réponse des soins de santé |
a web-based survey was conducted to decipher the approach of Indian doctors to the various options for treatment of
COVID-19. Findings show, 76% doctors would consider hydroxychloroquine as prophylaxis for healthcare providers against coronavirus disease19. |
|
|
García-Tascón, M, Sahelices-Pinto, et al |
International Journal of Environmental Research and Public Health |
Public Health response| Interventions de santé publique |
This study analyzes the impact of such confinement on the health of men and women, as well as the effect on the practice
of physical activity (PA) of both genders. For both genders, there was a significant decrease in quantity and intensity (p = 0.000). There was also an alteration in the type of PA practiced, shifting from cardiorespiratory exercise and muscular fitness to
flexibility and neuromotor exercise (especially in women). The most popular way of practicing PA during the confinement was “autonomously” (statistically higher in men (M = 3.58) compared to women (M = 3.18)) and the most frequent format was “virtual” (statistically
higher in women (M = 2.81) compared to men (M = 1.94)). Confinement modifies the habits of PA practice, especially in men. Both genders put their health and quality of life at risk by not following the PA guidelines of the health authorities World Health Organization
(WHO) and American College of Sports Medicine ACSM). These conclusions highlight the importance of considering gender when designing programs and PA formats for the promotion of physical activity to reduce the existing gender divide. |
|
|
Garg, A, Kumar, et al |
Environmental Claims Journal |
Public health interventions*| Interventions de santé publique |
The present study investigates the effect of lockdown on ambient air quality of 16 Indian cities constituting the major
hotspots for COVID-19 cases. The COVID-19 lockdown resulted in cleaner air in India. Significant reduction of nearly 62%, 52% and 69% are observed in PM10, PM2.5 and NO2 levels as compared to preceding years. However, there is no significant effect of lockdown
on other gaseous pollutants (SO2 and O3). The lockdown in India was found to be an effective way to restrict the virus spread rate and measure control ambient air pollutant levels. |
|
|
Anonymity Preserving IoT-Based COVID-19 and Other Infectious Disease Contact Tracing Model |
Garg, L, Chukwu, et al |
IEEE Access |
Public health interventions*| Interventions de santé publique |
In this article, we designed and presented a novel privacy anonymous IoT model. We presented an RFID proof-of-concept
for this model. Our model leverages blockchain's trust-oriented decentralization for on-chain data logging and retrieval. Our model solution will allow moving objects to receive or send notifications when they are close to a flagged, probable, or confirmed
diseased case, or flagged place or object. We implemented and presented three prototype blockchain smart contracts for our model. We then simulated contract deployments and execution of functions. We presented the cost differentials. Our simulation results
show less than one-second deployment and call time for smart contracts, though, in real life, it can be up to 25 seconds on Ethereum public blockchain. Our simulation results also show that it costs an average of $1.95 to deploy our prototype smart contracts,
and an average of $0.34 to call our functions. Our model will make it easy to identify clusters of infection contacts and help deliver a notification for mass isolation while preserving individual privacy. Furthermore, it can be used to understand better human
connectivity, model similar other infection spread network, and develop public policies to control the spread of COVID-19 while preparing for future epidemics. |
|
Ge, F, Zhang, et al |
Neuropsychiatric Disease and Treatment |
Public Health response| Interventions de santé publique |
We aimed to explore the prevalence rate of probable anxiety and probable insomnia and to find the risk factors among
a longitudinal study of undergraduate students using the approach of machine learning. The prevalence rate of probable anxiety and probable insomnia was 12.49% and 16.87%, respectively. The XGBoost algorithm predicted 1954 out of 2009 students (translated
into 97.3% accuracy) and 1932 out of 2009 students (translated into 96.2% accuracy) who suffered anxiety and insomnia symptoms, respectively. The most relevant variables in predicting probable anxiety included romantic relationship, suicidal ideation, sleep
symptoms, and a history of anxiety symptoms. The most relevant variables in predicting probable insomnia included aggression, psychotic experiences, suicidal ideation, and romantic relationship. |
|
|
Ghia, S, Bhatt, et al |
Journal of cardiothoracic and vascular anesthesia |
Clinical data| Données cliniques |
A patient who presented with COVID-19 pneumonia and whose condition rapidly deteriorated to respiratory failure requiring
intubation is described. Tissue plasminogen activator (tPA) was administered because of concern of pulmonary microemboli, with improvement of respiratory status and extubation within 24 hours. Patients with COVID-19 infection have an increased risk of thrombus
formation,1 and the administration of tPA may benefit these patients by immediately lysing diffuse thrombi and improving gas exchange. |
|
|
Ghorbani, A, Samarfard, et al |
Infection, Genetics and Evolution |
Coronavirology| Coronavirologie |
Using available High Throughput Sequencing (HTS) data and based on SARS-CoV-2 infected human transcriptomic data, this
study presents a high-resolution map of SARS-CoV-2 single nucleotide polymorphism (SNP) hotspots in a viral population at inter-host level. Twenty-two RNA modification sites on viral transcripts were identified that may cause inter-host genetic diversity of
this virus. In addition, the canonical genomic RNAs of N ORF showed higher expression in transcriptomic data and reverse transcriptase quantitative PCR compared to other SARS-CoV-2 ORFs, indicating the importance of this ORF in virus replication or other major
functions in virus cycle. Phylogenetic and ancestral sequence analyses based on the entire genome revealed that SARS-CoV-2 is possibly derived from a recombination event between SARS-CoV and Bat SARS-like CoV. Ancestor analysis of the isolates from different
locations including Iran suggest shared Chinese ancestry. These results propose the importance of potential inter-host level genetic variations to the evolution of SARS-COV-2, and the formation of viral quasi-species. The RNA modifications discovered in this
study may cause amino acid sequence changes in polyprotein, spike protein, product of ORF8 and nucleocapsid (N) protein, suggesting further insights to understanding the functional impacts of mutations in the life cycle and pathogenicity of SARS-CoV-2. |
|
|
Exploring dynamics and network analysis of spike glycoprotein of
SARS-COV-2 |
Ghorbani, Mahdi, Brooks, et al |
bioRxiv |
Coronavirology| Coronavirologie |
To study the dynamic motion of glycans in the spike protein, we performed microsecond-long MD simulation in two different
states that correspond to the receptor binding domain in open or closed conformations. Analysis of this microsecond-long simulation revealed a scissoring motion on the N-terminal domain of neighboring monomers in the spike trimer. Role of multiple glycans
in shielding of spike protein in different regions were uncovered by a network analysis, where the high betweenness centrality of glycans at the apex revealed their importance and function in the glycan shield. Microdomains of glycans were identified featuring
a high degree of intra-communication in these microdomains. An antibody overlap analysis revealed the glycan microdomains as well as individual glycans that inhibit access to the antibody epitopes on the spike protein. Overall, the results of this study provide
detailed understanding of the spike glycan shield, which may be utilized for therapeutic efforts against this crisis. |
|
OptCoNet: an optimized convolutional neural network for an automatic diagnosis of COVID-19 |
Goel, T, Murugan, et al |
Applied Intelligence |
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection
d'agents pathogènes |
This paper aims to classify COVID-19, normal, and pneumonia patients from chest X-ray images. As such, an Optimized
Convolutional Neural network (OptCoNet) is proposed in this work for the automatic diagnosis of COVID-19. The proposed OptCoNet architecture is composed of optimized feature extraction and classification components. The Grey Wolf Optimizer (GWO) algorithm
is used to optimize the hyperparameters for training the CNN layers. The proposed model is tested and compared with different classification strategies utilizing an openly accessible dataset of COVID-19, normal, and pneumonia images. The presented optimized
CNN model provides accuracy, sensitivity, specificity, precision, and F1 score values of 97.78%, 97.75%, 96.25%, 92.88%, and 95.25%, respectively, which are better than those of state-of-the-art models. This proposed CNN model can help in the automatic screening
of COVID-19 patients and decrease the burden on medicinal services frameworks. |
|
Potential Features of ICU Admission in X-ray Images of COVID-19 Patients |
Gomes, DouglasPS, Ulhaq, et al |
arXiv |
Clinical data| Données cliniques |
This paper presents a methodology for extracting features from a limited data set with outcome label (patient required
ICU admission or not) and correlating its significance to an additional, larger data set with hundreds of images. The methodology employs a neural network trained to recognise lung pathologies to extract the semantic features, which are then analysed with
a shallow decision tree to limit overfitting while increasing interpretability. This analysis points out that only a few features explain most of the variance between patients that developed severe symptoms. When applied to an unrelated, larger data set with
labels extracted from clinical notes, the method classified distinct sets of samples where there was a much higher frequency of labels such as `Consolidation', `Effusion', and `alveolar'. A further brief analysis on the locations of such labels also showed
a significant increase in the frequency of words like `bilateral', `middle', and `lower' in patients classified as with higher chances of going severe. The methodology for dealing with the lack of specific ICU label data while attesting correlations with a
data set containing text notes is novel; its results suggest that some pathologies should receive higher weights when assessing disease severity. |
|
Gómez-Galán, J, Martínez-López, et al |
Sustainability (Switzerland) |
Public Health response| Interventions de santé publique |
In this cross-sectional study, with a descriptive and quantitative methodology, students from 14 Spanish universities
were investigated in the first wave of the COVID-19 pandemic in order to understand the effects of this situation on the problem described. The results show a high consumption of social networks during that time, with significant incidences of addiction. In
parallel, the presence of comorbidity has been determined. In this scenario, it would be necessary to implement university educational programs to redirect these addictive behaviors, as well as preventative recommendations and actions to minimize negative
impacts. This is a major problem that is growing, exacerbated by the global pandemic produced by the SARS-CoV-2 coronavirus. Situations of this gravity call for the development of preventive and educational measures for the responsible and sustainable use
of ICT. |
|
|
Gómez-Salgado, J, Domínguez-Salas, et al |
Sustainability (Switzerland) |
Healthcare Response | Réponse des soins de santé |
This work aims to describe the levels of psychological distress and SOC of healthcare professionals during the crisis
caused by COVID-19, the relationship between both variables, and their health status. The results showed that 80.6% of healthcare professionals had psychological distress, and the mean score on the SOC-13 scale was 62.8 points (SD = 12.02). Both psychological
distress and SOC were related to the presence of COVID-19 symptoms, as well as with contact history. Professionals with psychological distress showed a lower SOC. Taking care of the mental health of healthcare professionals is essential to effectively cope
with the COVID-19 pandemic. Given the psychological impact of working in the current menacing scenario, people on the front line against the disease should be protected, minimizing risks, providing them with resources and support, and fostering their coping
skills. |
|
|
Características
iniciales de las políticas de control de la pandemia de Covid-19 en América Latina |
González, R |
Gaceta medica de Caracas |
Public health interventions*| Interventions de santé publique |
This study aims to characterize the policies implemented by Latin American countries for the control of the Covid-19
pandemic, especially in aspects related to the preparation and implementation phases. Analysis of the "Government Response Stringency Index (GRSI)" developed at the Blavatnik School of Government, University of Oxford, in 19 Latin American countries. Eight
countries in the region were identified that implemented control policies in the first stage of the pandemic, between 35 and 56 days before the registration of the first case of Covid-19. The average value of the GRSI from the registration of the first case
until May 17, 2020, allowed the classification of the countries into three groups according to the stringency of the policies: low, intermediate, and high. The effects of control policies are related to the structural conditions of the region's health systems. |
|
Grassi, R, Cappabianca, et al |
International Journal of Environmental Research and Public Health |
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection
d'agents pathogènes |
Thoracic VCAR software was not able to perform volumes segmentation in 26/162 (16.0%) cases, Myrian software in 12/162
(7.4%) patients while InferRead software in 61/162 (37.7%) patients. A great variability (ICC ranged for 0.17 to 0.51) was detected among the quantitative measurements of the residual healthy lung parenchyma volume, GGO, and consolidations volumes calculated
by different computer tools. The overall radiological severity score was moderately correlated with the residual healthy lung parenchyma volume obtained by ThoracicVCAR or Myrian software, with the GGO area obtained by the ThoracicVCAR tool and with consolidation
volume obtained by Myrian software. Quantified volumes by InferRead software had a low correlation with the overall radiological severity score. |
|
|
The role of perceived social support on depression and sleep during the COVID-19 pandemic |
Grey, I, Arora, et al |
Psychiatry research |
Public Health response| Interventions de santé publique |
The aim of the present study was to examine the role of perceived social support pertaining to a range of psychological
health outcomes amongst individuals undergoing social isolation and social distancing during COVID-19. A total of 2,020 participants provided responses to an online cross-sectional survey. Individuals experiencing self-isolation had significantly higher rates
of depression, irritability and loneliness compared to those who were not. The risk for elevated levels of depression symptoms was 63% lower in individuals who reported higher levels of social support compared to those with low perceived social support. Similarly,
those with high social support had a 52% lower risk of poor sleep quality compared to those with low social support. Social support was found to be significantly associated with elevated risk for depression and poorer sleep quality. |
|
Gualtieri, G, Brilli, et al |
Environmental Pollution |
Public health interventions*| Interventions de santé publique |
Six out of the eight most populated cities in Italy with different climatic conditions were analysed: Milan, Bologna,
Florence, Rome, Naples, and Palermo. NO2 levels remarkably dropped over all urban areas (from −24.9% in Milan to −59.1% in Naples), to an extent roughly proportional but lower than traffic reduction. Conversely, O3 concentrations remained unchanged or even
increased (up to 13.7% in Palermo and 14.7% in Rome), likely because of the reduced O3 titration triggered by lower NO emissions from vehicles, and lower NOx emissions over typical VOCs-limited environments such as urban areas, not compensated by comparable
VOCs emissions reductions. PM10 exhibited reductions up to 31.5% (Palermo) and increases up to 7.3% (Naples), while PM2.5 showed reductions of
∼13–17% counterbalanced by increases up to
∼9%. Higher household heating usage (+16–19% in March), also
driven by colder weather conditions than 2019 (−0.2 to −0.8 °C) may partly explain primary PM emissions increase, while an increase in agriculture activities may account for the NH3 emissions increase leading to secondary aerosol formation. |
|
|
Estimating the Impact of Daily Weather on the Temporal Pattern of COVID-19 Outbreak in India |
Gupta, A, Pradhan, et al |
Earth Systems and Environment |
Epidemiology| Épidémiologie |
Daily maximum (TMax), minimum (TMin), mean (TMean) and dew point temperature (TDew), wind speed (WS), relative humidity,
and diurnal range in temperature and relative humidity during March 01 to June 04, 2020 over 9 major affected cities are analyzed to look into the impact of daily weather on COVID-19 infections on that day and 7, 10, 12, 14, 16 days before those cases were
detected (i.e., on the likely transmission days). We conclude that coronavirus transmission is not well correlated (linearly) with any individual weather parameter; rather, transmission is susceptible to a certain weather pattern. Hence multivariate non-linear
approach must be employed instead. |
|
The Bass Model: a parsimonious and accurate approach to forecasting mortality caused by COVID-19 |
Gurumurthy, K, Mukherjee, et al |
International Journal of Pharmaceutical and Healthcare Marketing |
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie |
The purpose of this study is to present a simple, parsimonious and accurate model for forecasting mortality caused
by COVID-19. The findings of this paper show that compared to other forecasting methods, the Bass Model performs remarkably well. |
|
Halasa, T, Græsbøll, et al |
Frontiers in Veterinary Science |
Modelling/ prediction| Modélisation/prédiction |
We here present our experience with bringing our skills as veterinary disease modelers to bear on the field of human
epidemiology, building models as tools for decision makers, and bridging the gap between the medical and veterinary fields. We describe and compare the key steps taken in modeling the Sars-CoV-2 outbreak: criteria for model choices, model structure, contact
structure between individuals, transmission parameters, data availability, model validation, and disease management. Finally, we address how to improve on the contingency infrastructure available for Sars-CoV-2. |
|
|
Hamza, CA, Ewing, et al |
Canadian Psychology |
Public Health response| Interventions de santé publique |
Students filled out an online survey at both time points, reporting on their recent stressful experiences and mental
health. repeated-measures analyses demonstrated that students with preexisting mental health concerns showed improving or similar mental health during the pandemic (compared with one year prior). In contrast, students without preexisting mental health concerns
were more likely to show declining mental health, which coincided with increased social isolation among these students. |
|
|
Han, T |
Epidemiology and health |
Epidemiology| Épidémiologie Transmission |
We investigated the transmission of COVID-19 in a cluster of cases. We analyzed the epidemiological characteristics
of 10 confirmed COVID-19 patients in an outbreak that started at Spa facility A in a local community in Korea on March 28, 2020 and traced them through April 8, 2020. There were 3 male confirmed patients (30.0%) and 7 female confirmed patients (70.0%), and
their mean age was 53.5 years (range, 2.0 to 73.0). Two patients (20.0%) were asymptomatic. The incubation period was between 3 days and 12 days. Three confirmed patients were infected at female's Spa facility A and 7 confirmed patients were second, third,
and fourth generations of transmission. Seven confirmed patients contracted COVID-19 through presymptomatic contact. In total, 192 contacts were identified, with a secondary attack rate of 3.6%. Eighty-three contacts (43.2%) were aged 40-59 years, and the
secondary attack rate was the highest (12.1%) in those aged ≥60 years. Most exposures (n=156, 81.3%) involved casual contact. The number of visitors using the female's spa facility was 58, including 3 confirmed patients, resulting in a secondary outbreak rate
of 5.9%. |
|
|
The H1N1 factor and inverse correlation between death rates due to COVID-19 and influenza-pneumonia |
Haridas, A, Prathap, et al |
Current science |
Epidemiology| Épidémiologie |
In an earlier study, we had observed an inverse correlation between death rates due to COVID-19 and influenza, suggesting
cross-immunity. We examine virus surveillance data further to identify the key subtype of influenza virus that seems to give such crossimmunity. This is identified as the H1N1 strain and we show that a country where this strain was recently dominant has much
lower COVID-19 mortality rates. |
|
The Pathogenisis of COVID-19 Myocardial Injury: an Immunohistochemical Study of Postmortem
Biopsies |
Hartmann, Camila, dos Santos Miggiolaro, et al |
Research Square prepub |
Clinical data| Données cliniques |
This histopathological and immunohistochemical study seeks to clarify the pathogenesis and propose a mechanism with
pathways involved in COVID-19 myocardial injury. Postmortem minimally invasive autopsies were performed in six patients who died from COVID-19, and the myocardium samples were compared to a control patient. The pathogenesis of COVID-19 myocardial injury seems
to be related with pyroptosis leading to endothelial cell injury and disfunction. The subsequent inflammation with associated interstitial edema could explain the myocardial disfunction and arrythmias in these patients. Our findings also show that COVID-19
myocardial injury may cause myocardial fibrosis in the long term. |
|
Impact of COVID-19 on Hospital Admission of Acute Stroke patients
in Bangladesh |
Hasan, ATMH, Das, et al |
bioRxiv |
Healthcare Response | Réponse des soins de santé |
We conducted a retrospective analysis of stroke admissions in a 100-bed stroke unit at the National Institute of Neurosciences
and Hospital (NINS&H) which is considerably a large stroke unit. A total of 1394 stroke patients got admitted during the study period. From January to March, 2020 the mean rate of admission was 302.3 cases per month which dropped to 162.3 cases per month from
April to June with an overall reduction of 46.3% in acute stroke admission per month. In those two periods, reductions in average admission per month for ischemic stroke (IST), intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH) and venous stroke
(VS) were 45.5%, 37.2%, 71.4% and 39.0%, respectively. Only 38 patients (2.7%) were later found to be RT-PCR for SARS Cov-2 positive based on nasal swab testing. |
|
32954710; Population Risk Factors for COVID-19 Mortality in 93 Countries |
Hashim, MJ, Alsuwaidi, et al |
Journal of epidemiology and global health |
Epidemiology| Épidémiologie |
We aimed to study the variations in Case Mortality Rates (CMR) against population risk factors such as aging, underlying
chronic diseases and social determinants such as poverty and overcrowding. Bivariate analysis revealed that COVID-19 CMR were higher in countries that had high prevalence of population risk factors such as Alzheimer's Disease (AD), lung cancer, asthma and
COPD. On multivariate modeling however, AD, COPD, depression and higher GDP predicted increased death rates. Comorbid illnesses such as AD and lung diseases may be more influential than aging alone. |
|
Ml-based trading models: An investigation during covid-19 pandemic crisis |
Hattab, D |
|
Economics | Économie |
The aim of this paper is to investigate the effect of volatility surges during the COVID-19 pandemic crisis on long-term
investment trading rules. When applying these long-term investment trading rules to the CAC40 index, from May 2016 to May 2020, the finding is that both MLP-based and hybrid ARFIMA-MLP-based trading models show higher performances with a Sharpe Ratio close
to 2 and a Profit Ratio around 40% despite the COVID-19 crisis. |
|
32934806; Prediction of repurposed drugs for treating lung injury in COVID-19 |
He, B, Garmire, et al |
F1000Research |
Coronavirology| Coronavirologie Therapeutics| Thérapeutique |
We performed drug repositioning analysis to identify drug candidates that reverse gene expression pattern in L1000
lung cell line HCC515 treated with ACE2 inhibitor. We propose two candidate drugs, COL-3 (a chemically modified tetracycline) and CGP-60474 (a cyclin-dependent kinase inhibitor), for treating lung injuries in COVID-19. |
|
He, F, Xia, et al |
Diagnostic microbiology and infectious disease |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
COVID-19 positive (194) and negative (212) pneumonia patients were selected to analyze bacterial pathogens coinfection.
Results showed that 50% of COVID-19 patients were coinfected or carried bacterial pathogens. Bordetella pertussis infection rate was significantly higher in positive patients. |
|
|
He, TP, Wang, et al |
World Journal of Clinical Cases |
Clinical data| Données cliniques |
The patient, a 94-year-old female, lived in Maiji District of Tianshui, Gansu Province, China. On January 30, 2020,
she was admitted to the Fourth People's Hospital of Tianshui after 9 d of close contact with a patient with 2019-nCoV pneumonia. She was subsequently admitted to Gansu Provincial Hospital of Traditional Chinese Medicine for isolation and transferred to Tianshui
Gansu Provincial Hospital of Infectious Diseases on February 3, 2020 for treatment. Upon initial examination, her body temperature was 36.7°C, pulse was 80, breathing was 20, and blood pressure was 130/80 mmHg. She was conscious with normal development and
normal nutrition. The pharynx was not red, and bilateral tonsils were not red and swollen. The lungs sounded slightly coarse with no dry or wet rales. The first symptoms were cough and fatigue on 2 February. The patient was hospitalized for 12 d. After active
treatment, she was discharged on February 14 with a good prognosis. |
|
|
Head, KJ, Kasting, et al |
Science Communication |
Public Health response| Interventions de santé publique |
We conducted a survey (N = 3,159) with U.S. adults in May 2020 assessing SARS-CoV-2 vaccine intentions, intentions
with a provider recommendation, and sociodemographic and psychosocial variables. Participants had high SARS-CoV-2 vaccine intentions (M = 5.23/7-point scale), which increased significantly with a provider recommendation (M = 5.47). Hierarchical linear regression
showed that less education and working in health care were associated with lower intent, and liberal political views, altruism, and COVID-19-related health beliefs were associated with higher intent. |
|
|
Reimposing of marketed drugs in treatment of COVID 19 by insilicomethods |
Hemalatha, CN, Hemamalini, et al |
International Journal of Pharmaceutical Research |
Coronavirology| Coronavirologie Therapeutics| Thérapeutique |
The study was to investigate the binding efficiency of selected currently COVID 19 treating drugs and visualized by
Discovery Studio 4.1 Visualizer. The target sites of drugs selected for the study were extracted from Protein Data Bank, and the ligands selected for the study are (R1-R7)Among the compounds treated with targets are screened in Autodock. CompoundR5 shows greater
binding efficacy Results: Compound R5 shows better antiviral activity and inhibition and active protease inhibitor and promotes to treat Sars cov.2 (COVID-19). |
|
Hinojosa-Velasco, A, de Oca, et al |
International Journal of Infectious Diseases |
Clinical data| Données cliniques |
Although COVID-19 in pregnant women and their neonates has been demonstrated, there is not enough evidence about how
this vertical transmission occurs. This report describes a SARS-CoV-2 infection in a 21-year-old mother-daughter duo at the time of birth, focusing on the viral RNA detection in the stool of both and the human breast milk. © 2020 The Author(s) |
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Hou, Y, Zhou, et al |
Journal of Emergency Nursing |
Healthcare Response | Réponse des soins de santé |
Using qualitative research methods, semistructured interviews were conducted with 12 emergency nurses who met the inclusion
criteria, and Colaizzi analysis was used for data analysis, summary, and induction. Results: A cluster of 4 themes that involved preparedness of the emergency department during the COVID-19 outbreak was extracted: organizational preparedness, personal preparedness,
patient and family preparedness, and deficiencies and challenges. Organizations, individuals, patients, and family members were actively prepared to respond to novel coronavirus pneumonia outbreak in the emergency department. The emergency nurses said that
the trusted organization guaranteed personal preparedness, and the active cooperation from patients and families was a motivator for personal preparedness. In addition, our study showed that there were deficiencies in both multidisciplinary collaboration efforts
and efforts to rapidly diagnose and treat patients with fever in critical condition. |
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Hu, W, Dong, et al |
International Journal of COPD |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
: In this study, we investigated the acute exacerbation and outcomes of COPD patients during the outbreak of COVID-19
and evaluated the prevalence and mortality of COPD patients with confirmed COVID-19. A prospectively recruited cohort of 489 COPD patients was retrospectively followed-up for their conditions during the COVID-19 pandemic from December 2019 to March 2020 in
Hubei, China. In addition, the features of 821 discharged patients with confirmed COVID-19 were retrospectively analyzed. Of the 489 followed-up enrolled COPD patients, 2 cases were diagnosed as confirmed COVID-19, and 97 cases had exacerbations, 32 cases
of which were hospitalized, and 14 cases died. Compared with the 6-month follow-up results collected 1 year ago, in 307 cases of this cohort, the rates of exacerbations and hospitalization of the 489 COPD patients during the last 4 months decreased, while
the mortality rate increased significantly (2.86% vs 0.65%, p=0.023). Of the 821 patients with COVID-19, 37 cases (4.5%) had pre-existing COPD. Of 180 confirmed deaths, 19 cases (10.6%) were combined with COPD. Compared to COVID-19 deaths without COPD, COVID-19
deaths with COPD had higher rates of coronary artery disease and/ or cerebrovascular diseases. Old age, low BMI and low parameters of lung function were risk factors of all-cause mortality for COVID-19 patients with pre-existing COPD. |
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Inoue, Kazuo, Kashima, et al |
Research Square prepub |
Epidemiology| Épidémiologie |
Herein, we hypothesised that past tuberculosis epidemic may act as a latent explanatory factor for the worldwide difference
in COVID-19 impact. We compared two indicators of past tuberculosis epidemic, namely, incidence and mortality with COVID-19 mortality rate. The rate ratio of the cumulative COVID-19 mortality per 1 million was 1.08 (95% confidence interval [CI]: 0.98–1.18)
per 1 unit decrease in the incidence rate of tuberculosis per 100,000 people. This association existed even after adjusting for potential confounders (elderly rate, diabetes prevalence, mortality rate from cardiovascular disease, and gross domestic product
per capita) [adjusted rate ratio: 1.05, 95% CI: (1.03–1.08)]. |
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Retinal findings in patients with COVID-19: Results from the SERPICO-19 study |
Invernizzi, A, Torre, et al |
EClinicalMedicine |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
We screened the fundus of patients with COVID-19 to detect alterations of the retina and its vasculature and to assess
possible correlations with clinical parameters. 54 patients and 133 unexposed subjects were enrolled. Retinal findings in COVID-19 included: haemorrhages (9·25%), cotton wools spots (7·4%), dilated veins (27·7%), tortuous vessels (12·9%). Both Mean arteries
diameter (MAD) and veins diameter (MVD) were higher in COVID-19 patients compared to unexposed subjects. |
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Iriani, SS, Andjarwati, et al |
Systematic Reviews in Pharmacy |
Public Health response| Interventions de santé publique |
This study aims to analyze the influence of perceived usefulness, perceived ease of use, and perceived risk to-wards
online shopping decisions. The population in this study is housewives in East Java, Indonesia, as many as 100 people The analysis tool used in this study is multiple linear regressions. The results of this study show that there is a significant result of perceived
usefulness and perceived ease of use toward online shopping decision, while perceived risk variable does not have an influence toward online shopping decision. It is because online shopping risk is not the main aspect to consider, as consumers are more concerned
with the safety risks so as not to be infected with the Corona virus and get social sanctions from the community around. |
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Infectivity and Progression of COVID-19 Based on Selected Host Candidate Gene Variants |
Iyer, GR, Samajder, et al |
Frontiers in Genetics |
Clinical data| Données cliniques |
Host genes are involved in viral infectivity and pathogenicity, and polymorphisms in these could be responsible for
the interethnic/interindividual variability observed in infection and progression of COVID-19. Clinical exome data of 103 individuals was analyzed to identify sequence variants in five selected candidate genes: ACE2, TMPRSS2, CD209, IFITM3, and MUC5B to assess
their prevalence and role to understand the COVID-19 infectivity and progression in our population. A total of 497 polymorphisms were identified in the five selected genes in the exomes analyzed. The two polymorphisms described in literature as risk inducing
are rs35705950 in MUC5B gene and TMPRSS2 haplotype (rs463727, rs34624090, rs55964536, rs734056, rs4290734, rs34783969, rs11702475, rs35899679, and rs35041537) were absent in our cohort explaining the slower infectivity of the disease in this part of India. |
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Modelling logistic growth model for covid-19 pandemic in India |
Jain, M, Bhati, et al |
|
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie |
Generalized logistic growth, Logistic growth and Generalized growth models are used to predict the growth in the total
number of positive cases, daily increase in the number of positive tested cases and the daily growth rate in confirmed positive cases, dated from Apr 10, 2020, to Apr 20, 2020. 3 major growth parameters: r (Rate of growth at an early stage), K (Final epidemic
size) and C(Number of aggregate cases at time t) are calculated. Our models predict exponential and sub-exponential spread rate in the number of positive cases in India from Apr 10, 2020, to Apr 20, 2020. |
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Host transcriptomic profiling of COVID-19 patients with mild, moderate,
and severe clinical outcomes |
Jain, Ruchi, Ramaswamy, et al |
bioRxiv |
Clinical data| Données cliniques Coronavirology| Coronavirologie Immunology | Immunologie |
Perform shotgun transcriptome sequencing of human RNA obtained from nasopharyngeal swabs of patients with COVID-19,
and identify a molecular signature associated with disease severity. The excessive release of cytokines and chemokines such as CCL2, CCL22, CXCL9 and CXCL12 and certain interferons and interleukins related genes like IFIH1, IFI44, IFIT1 and IL10 were significantly
higher in patients with severe clinical presentation compared to mild and moderate presentations. Early induction of the TGF-β signaling pathway might be the primary cause of pulmonary fibrosis in patients with severe disease. |
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Jawad, YALA, Shalash, et al |
International Journal of Higher Education |
Public Health response| Interventions de santé publique |
This study examines the effect of E-learning during COVID-19 pandemic on the students’ Academic Achievement at Al-Quds
Open University. The study has randomly selected 382 students’ GPA from the University's official records. The study has revealed that there are statistically significant differences in the students’ Academic Achievements during the implementation of the E-learning
strategy in COVID-19 pandemic. his study shows that in general the GPA of students has increased about 2.188 points; but in particular the GPA of male students is affected more than female’s by just a slight difference of 1,198 point. |
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Potent antiviral effect of silver nanoparticles on SARS-CoV-2 |
Jeremiah, SS, Miyakawa, et al |
Biochemical and biophysical research communications |
Coronavirology| Coronavirologie Therapeutics| Thérapeutique |
The pandemic of COVID-19 is spreading unchecked due to the lack of effective antiviral measures. Silver nanoparticles
(AgNP) have been studied to possess antiviral properties and are presumed to inhibit SARS-CoV-2. Due to the need for an effective agent against SARS-CoV-2, we evaluated the antiviral effect of AgNPs. We evaluated a plethora of AgNPs of different sizes and
concentration and observed that particles of diameter around 10 nm were effective in inhibiting extracellular SARS-CoV-2 at concentrations ranging between 1 and 10 ppm while cytotoxic effect was observed at concentrations of 20 ppm and above. Luciferase-based
pseudovirus entry assay revealed that AgNPs potently inhibited viral entry step via disrupting viral integrity. These results indicate that AgNPs are highly potent microbicides against SARS-CoV-2 but should be used with caution due to their cytotoxic effects
and their potential to derange environmental ecosystems when improperly disposed. © 2020 Elsevier Ltd |
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Jeżewska-Zychowicz, M, Plichta, et al |
Nutrients |
Public Health response| Interventions de santé publique |
The present study aimed to investigate whether trust in circulating information and perceived stress are predictors
of consumers’ fear of limited access to food as well as predictors of food purchase behaviors during the COVID-19 pandemic. Logistic regression was used to estimate the likelihood of fear of limited access to food and the likelihood of purchase of larger amounts
of food than usual. The likelihood of experiencing fear of limited access to food increased by 16% with higher perceived stress, by 50% with higher trust in “Mass media and friends”, and by 219% with perceived changes in food availability in the previous month.
Trust in “Polish government institutions” decreased the chance of experiencing such fears by 22%. Government institutions may have difficulty in disseminating pandemic-related recommendations through media. |
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Cultural Differences in the Construal of Suffering and the COVID-19 Pandemic |
Ji, LJ, Khei, et al |
Social Psychological and Personality Science |
Public Health response| Interventions de santé publique |
The present research examines how suffering is construed across cultures. Study 1 (N1 = 264; N2 = 745) asked participants
to provide free associations for suffering. Chinese individuals generated more positive associations than did Euro-Canadians. Study 2 (N = 522) had participants create a hypothetical potion of suffering to represent what people would experience while suffering.
Chinese participants added more positive ingredients and fewer negative ingredients than Euro-Canadians did. How would cultural differences in the construal of suffering matter in a real-life negative situation? Study 3 (N = 608) showed that Chinese participants
generated a greater proportion of potential positive outcomes for the COVID-19 outbreak and reported more positive affect during the pandemic than did Euro-Canadians. Thus, Chinese construe suffering more positively than Euro-Canadians. These findings are
consistent with previous research on cultural differences in dialectical thinking and lay theory of change and have implications for coping and resilience. © The Author(s) 2020. |
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Jiang, Q |
International Social Work |
Public Health response| Interventions de santé publique |
This essay examines how a small-scale non-governmental organization mobilizes community members in Montreal, Canada,
to respond to the city’s shortage of personal protective equipment during COVID-19 by making more than 1600 scrub caps for local healthcare workers. As the CAP-MTL project has progressed, organizers have constantly adjusted how they run the project in order
to meet evolving needs through three major phases: (1) centralizing resource allocation, (2) building a self-sufficient production team and (3) pairing volunteers with healthcare workers. This case study highlights how in crisis response projects, organizers
must be flexible and adapt to fluid and dynamic situations. © The Author(s) 2020. |
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Jin, Fei, Wang, et al |
bioRxiv |
Coronavirology| Coronavirologie |
In this study, we developed an FSEC assay utilizing nanobody (Nb) technology, named FSEC-Nb, in which targeted membrane
proteins are fused to a small peptide tag and recombinantly expressed. We applied FSEC-Nb to screen zinc-activated ion channel (ZAC) family proteins in the Cys-loop superfamily and membrane proteins from SARS-CoV-2 as examples of the practical application
of FSEC-Nb. We successfully identified a ZAC ortholog with high monodispersity but moderate expression levels that could not be identified with the previously developed GFP fusion-free FSEC method. Overall, our results show FSEC-Nb as a powerful tool for
membrane protein expression screening that can provide further opportunity to prepare well-behaved membrane proteins for structural and functional studies. |
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Justman, N, Shahak, et al |
The Israel Medical Association journal : IMAJ |
Healthcare Response | Réponse des soins de santé |
The authors conducted a cross-sectional study to describe changes in outpatient clinic visits and to compare the rates
of cesarean and instrumental deliveries between two periods of time: March-April 2020 (during the COVID-19 outbreak) with March-April of the preceding year, 2019. During the COVID-19 outbreak, visits to obstetric triage, gynecologic triage, high-risk clinic,
and ultrasound units decreased by 36.4%, 34.7%, 32.8%, and 18.1%, respectively. The medical center experienced a 17.8% drop in the total number of births (610 births) compared with March and April 2019 (742 births). During the outbreak women were more likely
to be nulliparous (33.3% vs. 27.6%, P = 0.02) and present with hypertensive disorders during pregnancy (7.5% vs. 4%, P = 0.005) or gestational diabetes (13% vs. 10%, P = 0.03). The medical facility experienced a major decline in all aspects of the routine
obstetrics activities during the time of the pandemic. |
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Kamenidou, I, Stavrianea, et al |
International Journal of Environmental Research and Public Health |
Public Health response| Interventions de santé publique |
This paper explores the generation Z (Gen Z) cohort’s self-assessed knowledge regarding the coronavirus disease 2019
(COVID-19) symptoms as well as their interest in acquiring information and learning more about the transmission and spread of the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2 virus) and the COVID-19 symptoms. Field research employing a nonprobability
sampling method with an online questionnaire resulted in collecting 762 valid questionnaires. Results reveal that overall symptom knowledge was assessed higher than the self-assessed knowledge of the 13 specific symptoms. |
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A deep learning framework to detect Covid-19 disease via chest X-ray and CT scan images |
Kamil, MY |
International Journal of Electrical and Computer Engineering |
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection
d'agents pathogènes |
In this work, a deep learning model was modified to Covid-19 detection via features extraction from chest X-ray and
CT images. Initially, many transfer-learning models have applied and comparison it, then a VGG-19 model was tuned to get the best results that can be adopted in the disease diagnosis. Diagnostic performance was assessed for all models used via the dataset
that included 1000 images. The VGG-19 model achieved the highest accuracy of 99%, sensitivity of 97.4%, and specificity of 99.4%. The deep learning and image processing demonstrated high performance in early Covid-19 detection. |
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Kapitány-Fövény, M, Sulyok, et al |
Humanities and Social Sciences Communications |
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie |
In order to investigate how certain social norms may underlie the heterogeneity of the spread of infections, global
social data (including cultural values, indices of prosperity, and government effectiveness) and covariates (such as climate zone, economic indicator, and healthcare access and quality) of early transmission dynamics of COVID-19 were collected. Model-based
clustering and random forest regression analysis were applied to identify distinct groups of societies and explore predictors of COVID-19 doubling time. Clustering revealed four groups: (1) reserved; (2) drifting; (3) assertive; and (4) compliant societies.
Compliant societies from dry climate zones showed the highest doubling times in spite of increased population densities. Most relevant predictors of doubling time were population density, freedom of assembly and association, and agency, underlining the importance
of social factors in the hetereogeneity of COVID-19 transmission rates. |
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Homeless shelter characteristics and prevalence of SARS-CoV-2 |
Karb, R, Samuels, et al |
Western Journal of Emergency Medicine |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
The purpose of this study was to identify shelter characteristics that may be associated with higher transmission of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We conducted a cross-sectional assessment of five congregate shelters in Rhode Island. A total of 299 shelter residents (99%, 299/302) participated. Thirty-five (11.7%) tested positive for SARS-CoV-2.
Shelter-level prevalence ranged from zero to 35%. SARS-CoV-2 prevalence varies with shelter characteristics but not individual symptoms. Policies that promote resident stability and physical distancing may help reduce SARS-CoV-2 transmission. Symptom screening
alone is insufficient to prevent SARS-CoV-2 transmission. |
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A case report on spontaneous hemoperitoneum in COVID-19 patient |
Karki, S, Rawal, et al |
International Journal of Surgery Case Reports |
Clinical data| Données cliniques |
A 35 year young otherwise healthy male presented to emergency department of this institute with fever of 103 °F, abdominal
pain, and pancytopenia with progressive fall in hemoglobin level was tested positive for COVID-19. Respiratory and gastrointestinal symptoms with hematological abnormalities like lymphopenia, thrombocytopenia are common presentation of COVID-19. Although coagulopathy
and vasculitis has been a well-documented entity in patients with COIVD-19, visceral infarction leading to spontaneous hemoperitoeum was unusual and rare clinical presentation. A high degree of clinical suspicion and thorough evaluation helps in the diagnosis
of COVID-19 and related complications. |
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Kase, Y, Okano, et al |
Inflammation and Regeneration |
Coronavirology| Coronavirologie Therapeutics| Thérapeutique |
Our present study showed that angiotensin-converting enzyme-2 (ACE2), a cellular receptor for SARS-CoV-2, is expressed
in human induced pluripotent stem cell (iPSC)-derived neural stem/progenitor cells (hiPSC-NS/PCs) and young neurons. Furthermore, together with database analysis, we found that a viral virulent factor CCN family member 1 (CCN1), which is known to be induced
by SARS-CoV-2 infection, is expressed in these cells at basal levels. Considering the role of CCN1 which is known to be involved in viral toxicity and inflammation, hiPSC-NS/PCs could provide an excellent model for COVID-19-associated CNS disorders from the
aspect of SARS-CoV-2 infection-ACE2-CCN1 axis. In addition, we identified compounds that reduce CCN1 expression. Collectively, our study using hiPSC-NS/PCs may aid in the development of a therapeutic target for COVID-19-related CNS disorders. |
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Diagnostic and prognostic value of chest radiographs for COVID-19 at presentation |
Kerpel, A, Apter, et al |
Western Journal of Emergency Medicine |
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection
d'agents pathogènes |
The purpose of this study was to assess the diagnostic and prognostic value of chest radiographs (CXR) for coronavirus
disease 2019 (COVID-19) at presentation. We retrospectively identified consecutive reverse transcription polymerase reaction-confirmed COVID-19 patients (n = 104, 75% men) and patients (n = 75, 51% men) with repeated negative severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) tests. wo radiologists blindly and independently reviewed the CXRs, documented findings, assigned radiographic assessment of lung edema (RALE) scores, and predicted the patients' COVID-19 status. The overall RALE score failed to
identify COVID-19 patients at presentation. However, the score was inversely correlated with a COVID-19 diagnosis within ≤2 days, and a positive correlation was found six days after symptom onset. Chest radiography was found not to be a valid diagnostic tool
for COVID-19, as normal or near-normal CXRs are more likely early in the disease course. |
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SARS-CoV-2 infection presenting as colitis with chest and abdomen CT findings |
Khader, M, Al Bishawi, et al |
Radiology Case Reports |
Clinical data| Données cliniques |
This study present a case of SARS-CoV-2 infection of a 40-year-old lady who presented with GI manifestations and features
of colitis of the caecum and ascending colon on CT scan. The patient did not have respiratory symptoms but had incidental lung changes in the visualized lung bases. These features were completely resolved as evident clinically and on follow-up CT scan after
only 2 weeks, with only supportive care for SARS-CoV-2 infection. |
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Khan, Wasiq, Hussain, et al |
arXiv |
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie |
In this study, we present an intelligent model to investigate the multi-dimensional associations between the potentially
relevant demographic attributes and the COVID_19 severity levels across the globe. We gather multiple demographic attributes and COVID_19 infection data (by 20 August 2020) from various reliable sources, which is then fed-into pattern matching algorithms that
include self-organizing maps, class association rules and statistical approaches, to identify the significant associations within the processed dataset. Statistical results and the experts report indicate strong associations between the COVID_19 severity levels
and measures of certain demographic attributes such as female smokers, when combined together with other attributes. These results strongly suggest that the mechanism underlying COVID_19 infection severity is associated to distribution of the certain demographic
attributes within different regions of the world. |
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Deep Learning-based Four-region Lung Segmentation in Chest Radiography for COVID-19 Diagnosis |
Kim, Young-Gon, Kim, et al |
arXiv |
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection
d'agents pathogènes |
Most current AI assisted CXR image analysis framework do not quantify for regional variations of disease. To address
these, we proposed a four region lung segmentation method to assist accurate quantification of COVID 19 pneumonia. A segmentation model to separate left and right lung is firstly applied, and then a carina and left hilum detection network is used, which are
the clinical landmarks to separate the upper and lower lungs. The proposed ensemble strategy showed dice score of 0.900, which is significantly higher than conventional methods (0.854 0.889). |
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Knox, DB, Lanspa, et al |
Neurohospitalist |
Healthcare Response | Réponse des soins de santé |
Stroke is a catastrophic medical disease with roughly 795,000 cases per year in the US. We strove to explore whether
stroke admissions to a comprehensive stroke center in an area with moderately-low COVID-19 burden changed and if so, to better define the characteristics of the patients and their presentation. We performed a retrospective analysis of all patients with strokes
admitted to Intermountain Medical Center. There was a 43% reduction in patients’ presentations across all stroke types compared to average April patient volume over the prior 3 years. Likely this was due to a myriad of complex factors which we may retrospectively
be able to more fully understand in the years to come. © The Author(s) 2020. |
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Koh, JS, De Silva, et al |
Journal of the neurological sciences |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
To describe the spectrum of COVID-19 neurology in Singapore. We prospectively studied all microbiologically-confirmed
COVID-19 patients in Singapore, who were referred for any neurological complaint within three months of COVID-19 onset. 47,572 patients (median age 34 years, 98% males) were diagnosed with COVID-19 in Singapore between 19 March to 19 July 2020. We identified
90 patients (median age 38, 98.9% males) with neurological disorders. AIS/TIA was variable in onset, occurring in patients with differing COVID-19 severity; remarkably 63.2% were asymptomatic. COVID-19 neurology has a wide spectrum of dysimmune-thrombotic
disorders. |
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Kotb, H, Khalil, et al |
|
Modelling/ prediction| Modélisation/prédiction Transmission |
This work presents the results of a study of airflow behavior of coughing and sneezing droplets that are produced from
a moving passenger in wide-body aircraft cabin section at different velocity rates. In addition, it compared between transmission of different flow rates and velocities in order to show how can these diseases transported from a moving and standing passenger
to other passengers. This numerical simulation used computational fluid dynamic (CFD) modeling simulation. The results showed that the airflow of coughing and sneezing droplets produced from the moving passengers could reach seated passengers; however, sneezed
droplets had more harmful impacts than coughed droplets, also both travelled for a long distance inside the cabin. In addition, when comparing the droplets spread range resulting from the moving passenger and stand-still one, it was found that the quicker
the passenger moves, the further the droplets spread. |
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Kottlors, J, Zopfs, et al |
European Journal of Radiology |
Clinical data| Données cliniques Healthcare Response | Réponse des soins de santé |
We investigated whether the ratio of fat to muscle area, measured in initial low-dose computed tomography (LDCT), can
predict severe progression of COVID-19 in the follow-up period. We analyzed 58 individuals with confirmed COVID-19 infection that underwent an initial LDCT in one of two included centers due to COVID-19 infection. Using the ratio of waist circumference per
paravertebral muscle circumference (FMR), the body composition was estimated. Patient outcomes were rated on an ordinal scale with higher numbers representing more severe progression or disease associated complications (hospitalization/ intensive care unit
(ICU)/ tracheal intubation/ death) within a follow-up period of 22 days after initial LDCT. In the initial LDCT a significantly higher FMR was found in patients requiring intensive care treatment within the follow-up period. In multivariate logistic regression
analysis, FMR (p <.001) in addition to age (p <.01), was found to be a significant predictor of the necessity for ICU treatment of COVID-19 patients. FMR as potential surrogate of body composition and obesity can be easily determined in initial LDCT of COVID-19
patients. Within the multivariate analysis, in addition to patient age, low muscle area in proportion to high fat area represents an additional prognostic information for the patient outcome and the need of an ICU treatment during the follow-up period within
the next 22 days. |
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Delayed SARS-COV-2 leukoencephalopathy without Severe Hypoxia |
Kumar, A, Olivera, et al |
Journal of the neurological sciences |
Clinical data| Données cliniques |
This is a case study of a 35-year-old African American female with history of gastric bypass surgery and iron deficiency
anemia had a positive nasopharyngeal swab for SARS-CoV-2 PCR in April 2020 in the setting of anosmia and ageusia. The patient developed encephalopathy two months after a mild case of COVID-19. MRI Brain demonstrated extensive white matter lesions juxtacortically
and subcortically. Workup for infectious, paraneoplastic, toxic process was negative. MBP was elevated, prompting diagnosis of post-infectious ADEM following COVID-19. COVID-19 patients without hypoxia may have post-infectious leukoencephalopathy. |
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Describing the experiences of older persons with visual impairments
during COVID-19 in rural Ghana |
Kwegyir Tsiboe, A |
Journal of Adult Protection |
Public Health response| Interventions de santé publique |
This study aims to describe the lived experiences among older persons with disability during the coronavirus pandemic
in rural Ghana. This study is based on a qualitative methodology consistent with a phenomenological approach. Semi-structured interviews were conducted with 20 participants. Thematic analysis was used for data analysis. During the pandemic, care rendered to
older persons with disabilities by their caregivers easily declined because of the lockdown measure. This made the participants suffer in profound loneliness and hunger, and forced some to generate suicidal thoughts. On the other hand, the participants who
lived with their family members were also kept indoors for several weeks to reduce their chances of contracting the virus. This was because participants’ family members losed confidence in the Ghanaian health-care system in protecting their older relatives. |
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La Porta, CAM, Zapperi, et al |
Cell Systems |
Coronavirology| Coronavirologie |
This study uses artificial neural networks to analyze the binding of SARS-CoV-2 peptides with polymorphic human MHC
class I molecules. The authors identified two sets of haplotypes present in specific human populations: the first displays weak binding with SARS-CoV-2 peptides, while the second shows strong binding and T cell propensity. Our work offers a useful support
to identify the individual susceptibility to COVID-19 and illustrates a mechanism underlying variations in the immune response to SARS-CoV-2. |
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Barrier enclosure for endotracheal intubation in a simulated COVID-19 Scenario: A crossover study |
Laack, TA, Pollok, et al |
Western Journal of Emergency Medicine |
Healthcare Response | Réponse des soins de santé |
We sought to determine whether a barrier enclosure delays time to successful intubation by experienced airway operators.
We conducted a crossover simulation study at a tertiary academic hospital. Participants watched a four-minute video, practiced one simulated intubation with a barrier enclosure, and then completed one intubation with and one without the barrier enclosure (randomized
to determine order). The primary outcome measure was time from placement of the video laryngoscope at the lips to first delivered ventilation. Secondary outcomes were periprocedural complications and participant responses to a post-study survey. Proceduralists
(n = 50) from emergency medicine and anesthesiology had median intubation times of 23.6 seconds with practice barrier enclosure, 20.5 seconds with barrier enclosure, and 16.7 seconds with no barrier. Intubation with barrier enclosure averaged 4.5 seconds longer
(95% confidence interval, 2.7-6.4, p < .001) than without, but was less than the predetermined clinical significance threshold of 10 seconds. Three complications occurred, all during the practice intubation. Barrier enclosure made intubation more challenging
according to 48%, but 90% indicated they would consider using it in clinical practice. Given potential to reduce droplet spread, use of a barrier enclosure may be an acceptable adjunct to endotracheal intubation for those familiar with its use. |
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Lai, IKW, Wong, et al |
International Journal of Contemporary Hospitality Management |
Economics | Économie |
This study aims to compare how the hotel industry has responded to this COVID-19 crisis at the initial stage and the
pandemic stage. Data were collected from hotel managers in Macau in two occasions, early February and early April 2020. Importance-usage-performance analysis was conducted to classify six categories of practices (pricing, marketing, maintenance, human resources,
government assistance and epidemic prevention) into four executable crisis management strategies (priority, maintain, low priority and possible overkill) for each stage. Follow-up in-person interviews were conducted to validate the results of the study. In
the initial stage, priority strategies should be applied in all epidemic prevention, pricing and maintenance practices and in two governmental assistance and human resources practices. In the pandemic stage, all epidemic prevention practices remain at the
priority quadrant, but two pricing practices are downgraded. Hotels tended to force labour into unpaid vacations (furlough) and postpone office and system maintenance. Governmental assistance should be at a low priority. |
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How macroscopic laws describe complex dynamics: Asymptomatic population and Covid-19 spreading |
Lanteri, D, Carco, et al |
International Journal of Modern Physics C |
Modelling/ prediction| Modélisation/prédiction Transmission |
The considered model of Covid-19 spreading is based on a system of coupled differential equations, which include the
dynamics of the spreading among symptomatic and asymptomatic individuals and the strong containment effects due to the social isolation. The solution has been compared with N(t), determined by a single differential equation with no explicit reference to A(t),
showing the equivalence of the two methods. The model is applied to Covid-19 spreading in Italy where a transition from an exponential behavior to a Gompertz growth for N(t) has been observed in more recent data. The information contained in the time series
N(t) turns out to be reliable to understand the epidemic phase, although it does not describe the total infected population. The asymptomatic population is larger than the symptomatic one in the fast growth phase of the spreading. |
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Leveraging Trends in Neurology Admissions for Departmental Planning During the
COVID-19 Pandemic |
Lau, KHV, Anand, et al |
Neurohospitalist |
Healthcare Response | Réponse des soins de santé |
We aimed to determine how trends in neurology service admissions during the pandemic may aid in departmental planning
by predicting future clinician staffing and other needs. We examined all admissions to the general neurology, stroke, and neurocritical care services from January 31 to May 16, 2020 at our tertiary-care hospital using an electronic health record query, comparing
these to analogous data in 2019. We trended admission rates and projected future censuses using logarithmic regression, tracked changes in length of stay (LOS), and quantified shifts in presentations of specific diagnoses. Daily rates of admissions declined
sharply during the week of March 13, 2020. On the censoring date, we projected a return to pre-pandemic censuses in the week of June 21 and used this information to make decisions regarding neurology resident schedules. There was a trend toward increased LOS
for general neurology and stroke patients between March 27 and April 9, 2020 compared to in 2019, with subsequent decline coinciding with early hospital initiatives. Since March 13, 2020, there has been a trend toward reduced presentations of ischemic stroke,
suggesting a need for community education on stroke awareness. |
|
Minimum sizes of respiratory particles carrying SARS-CoV-2 and the possibility of aerosol generation |
Lee, BU |
International Journal of Environmental Research and Public Health |
Modelling/ prediction| Modélisation/prédiction Transmission |
This study calculates and elucidates the minimum size of respiratory particles that are potential carriers of the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2); furthermore, it evaluates the aerosol generation potential of SARS-CoV-2. The calculations are based on experimental results and theoretical models. In the case of maximum viral-loading derived from experimental
data of COVID-19 patients, 7.18 × 10−4% of a respiratory fluid particle from a COVID-19 patient is occupied by SARS-CoV-2. Hence, the minimum size of a respiratory particle that can contain SARS-CoV-2 is calculated to be approximately 4.7 µm. The minimum size
of the particles can decrease due to the evaporation of water on the particle surfaces. There are limitations to this analysis: (a) assumption that the viruses are homogeneously distributed in respiratory fluid particles and (b) considering a gene copy as
a single virion in unit conversions. The study shows that high viral loads can decrease the minimum size of respiratory particles containing SARS-CoV-2, thereby increasing the probability of aerosol generation of the viruses. |
|
Lemos, ACB, do Espírito Santo, et al |
Thrombosis research |
Clinical data| Données cliniques Therapeutics| Thérapeutique RCT |
In this randomized, open-label, phase II study, we randomized COVID-19 patients requiring mechanical ventilation to
receive either therapeutic enoxaparin or the standard anticoagulant thromboprophylaxis. We evaluated the gas exchange over time through the ratio of partial pressure of arterial oxygen (PaO2) to the fraction of inspired oxygen (FiO2) at baseline, 7, and 14
days after randomization, the time until successful liberation from mechanical ventilation, and the ventilator-free days. Ten patients were assigned to the therapeutic enoxaparin and ten patients to prophylactic anticoagulation. There was a statistically
significant increase in the PaO2/FiO2 ratio over time in the therapeutic group (163 95% confidence interval – CI 133–193] at baseline, 209 95% CI 171–247] after 7 days, and 261 95% CI 230–293] after 14 days), p = 0.0004. In contrast, we did not observe this
improvement over time in the prophylactic group (184 95% CI 146–222] at baseline, 168 95% CI 142–195] after 7 days, and 195 95% CI 128–262] after 14 days), p = 0.487. Patients of the therapeutic group had a higher ratio of successful liberation from mechanical
ventilation (hazard ratio: 4.0 95% CI 1.035–15.053]), p = 0.031 and more ventilator-free days (15 days interquartile range IQR 6–16] versus 0 days IQR 0–11]), p = 0.028 when compared to the prophylactic group. Therapeutic enoxaparin improves gas exchange and
decreases the need for mechanical ventilation in severe COVID–19. Trial registration: REBEC RBR-949z6v. |
|
|
Sars-CoV-2 isolation from a 10-day-old newborn in Italy:
A case report |
Lenoci, G, Galante, et al |
IDCases |
Clinical data| Données cliniques |
This report describes the evolution of COVID-19 in a 10 day-old-baby. The mother developed the disease immediately
after childbirth and therefore a vertical transmission can be excluded. The isolation of the virus in cell culture with a cytopathic effect already visible after 48 h, indicates that the viral load of the newborn was quite high, but not serious course of the
disease was observed. This paper wants to highlight the possible role of newborns and children in the spread of the disease. © 2020 |
|
Analysis of the Risk Factors for Mortality in Adult COVID-19 Patients
in Wuhan: A Multicenter Study |
Li, M, Cheng, et al |
Frontiers in Medicine |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
Ths study explored the risk factors associated with COVID-19-related mortality in Wuhan, China. A total of 245 adult
patients with laboratory-confirmed COVID-19 from two centers were analyzed. Chi-square, Fisher's exact, and the Mann-Whitney U-tests were used to compare the clinical characteristics between the survivors and non-survivors. To explore the risk factors associated
with in-hospital death, univariable and multivariable cox regression analyses were used. Of the 245 patients included in this study, 23 (9.4%) died in the hospital. The multivariate regression analysis showed increased odds of in-hospital deaths associated
with age, D-dimer levels >1,000 ng/L, platelet count <125, and higher serum creatinine levels. The findings provide valuable references for clinicians to identify high-risk patients with COVID-19 at an early stage. |
|
32769260; Abnormal liver-related
biomarkers in COVID-19 patients and the role of prealbumin |
Li, T, Guo, et al |
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association |
Clinical data| Données cliniques |
This study evaluated the distribution of abnormal liver-related biomarkers in patients with coronavirus disease (COVID-19)
and explore the prognostic value of elevated liver enzymes and abnormal liver synthetic capacity with regards to patient mortality. This retrospective observational study included 80 laboratory-confirmed COVID-19 cases. Data were collected from the electronic
medical record system. Alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TB), albumin, and prealbumin levels at admission and on day 7 after admission were collected. The primary outcome of the current study was patient mortality.
Abnormal ALT, AST, TB, albumin, and prealbumin levels were observed in 11 (13.8%), 15 (18.8%), 5 (6.3%), 22 (27.5%), and 31 (38.8%) patients, respectively. Male gender correlated with elevated ALT and AST levels (p = 0.027 and 0.036, respectively). Higher
levels of AST and lower levels of albumin and prealbumin were associated with patient mortality (p = 0.009, 0.002, and 0.003, respectively). Multivariate Cox regression analysis identified patient age (p = 0.013, HR 1.108) and prealbumin levels (p = 0.015,
HR 0.986) as independent predictors for patient mortality. Changes in liver-related biomarkers were not associated with poor outcome in multivariate analysis (p > 0.05). Abnormalities in albumin and prealbumin levels are common among COVID-19 patients and
hypoprealbuminemia independently predicts adverse outcome and should be carefully considered in clinical practice. |
|
Li, W, Thomas, et al |
Earth Systems and Environment |
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie |
In this follow-up study, Aerosol Optical Depth (AOD) was introduced in conjunction with other variables like nitrogen
dioxide and population density for further analysis in fifty-four administrative regions of Germany, Italy and Spain. The AOD values were extracted from the Moderate Resolution Imaging Spectroradiometer (MODIS) onboard the Terra and Aqua satellites while the
nitrogen dioxide data were extracted from TROPOMI (TROPOspheric Monitoring Instrument) sensor onboard the Sentinel-5 Precursor satellite. Regression models, as well as multiple statistical tests were used to evaluate the predictive skill and significance of
each variable to the fatality rate. The study was conducted for two periods: (1) pre-exposure period (Dec 1, 2019–Feb 29, 2020); (2) complete exposure period (Dec 1, 2019–Jul 1, 2020). Some of the results pointed towards AOD potentially being a factor in estimating
the coronavirus fatality rate. The models performed better using the data collected during the complete exposure period, which showed higher AOD values contributed to an increased significance of AOD in the models. Meanwhile, some uncertainties of the analytical
results could be attributed to data quality and the absence of other important factors that determine the coronavirus fatality rate. |
|
|
Unsupervised clustering analysis reveals global population structure
of SARS-CoV-2 |
Li, Yawei, Liu, et al |
bioRxiv |
Epidemiology| Épidémiologie Coronavirology| Coronavirologie |
This study applied unsupervised clustering algorithms to group 16,873 SARS-CoV-2 strains, which automatically minimize
intra-cluster distances and maximize inter-cluster distances. Six distinct genomic clusters were identified, with mutation profiles as input features. The varied proportions of the six clusters within different continents revealed specific geographical distributions.
Comprehensive analysis indicated that genetic factors and human migration played an important role in shaping the specific geographical distribution of population structure. This study provides a concrete framework for the use of clustering methods in phylogenetic
analysis to study the global population structure of SARS-CoV-2. In addition, clustering methods can be used for future studies of variant population structures in specific regions of these fast-growing viruses. |
|
Liang, SW, Chen, et al |
Frontiers in Psychology |
Public Health response| Interventions de santé publique |
This study investigated the relationship between college students’ mental health status and psychological help-seeking
behavior to test the phases-decision-making model (PDM). A cross-sectional survey was conducted among college students in Guangdong Province using an online platform. In total, 4,164 students were assigned to the “counseling group” or “non-counseling group”
according to whether they had sought psychological help because of the COVID-19 outbreak; the groups were matched based on age, sex, and grade. Demographics, perceived mental health, and experience with seeking psychological help were recorded. Fear, depression,
and trauma were assessed by the COVID-19 Fear Screening Scale, Patient Health Questionnaire, and Impact of Event Scale-6. The fear, depression, and trauma scores were significantly higher in the counseling group than in the non-counseling group (Ps < 0.001).
Fear (OR = 1.27, p < 0.001), depression (OR = 1.02, p = 0.032), trauma (OR = 1.08, p < 0.001), poor perceived mental health status (OR = 3.61, p = 0.001), and experience with seeking psychological help (OR = 7.06, p < 0.001) increased the odds of seeking psychological
help. During the COVID-19 epidemic, the rate of psychological help-seeking was still low, and college students in poor psychological condition sought psychological counseling more. Fear, depression, trauma, experience with seeking psychological help, and perceived
mental health can effectively predict psychological help-seeking behavior. |
|
|
Lim, CY, Bohn, et al |
Clinical biochemistry |
Modelling/ prediction| Modélisation/prédiction Transmission Public health interventions*|
Interventions de santé publique |
A discrete event simulation was used to explore the impact of different permutations of staff roster, including the
number of shifts per day, the number of staff on duty per shift, overall number of staff accessible to work in the laboratory (i.e. overall staff pool), the frequency of shift changes (i.e. number of consecutive days worked), fixed work-rest days and split
team arrangement on workplace transmission of COVID-19 by a simulated index staff who acquired the infection from the community over 21 days. Additionally, the impact of workplace social distancing (physical distancing) and use of personal protective equipment
(PPE) were investigated. A higher rate of transmission was associated with smaller overall staff pool (expressed as multiples of the number of staff per shift), higher number of shifts per day, higher number of staff per shift, and longer consecutive days
worked. Having fixed work-rest arrangement did not significantly reduce the transmission rate unless the workplace outbreak was prolonged. Social distancing and PPE use significantly reduced the transmission rate. Laboratories should consider organizing the
staff into smaller teams/shift and reduce the number of consecutive days worked. |
|
|
32880904; COVID-19 in patients with hidradenitis suppurativa |
Lima, XT, Cueva, et al |
British Journal of Dermatology |
Clinical data| Données cliniques |
This retrospective cohort study aimed to evaluate the outcomes of patients with hidradenitis suppurativa (HS) who had
confirmed COVID‐19. Data was collected from the Research Patient Data Registry, a clinical data registry from various Partners Healthcare System (PHS) affiliated hospitals in the Boston area. As of 25 June 2020, of around 12 330 confirmed COVID cases in PHS,
approximately 24·0%, 7·7% and 4·5% were admitted to hospital, a critical care unit and/or died, respectively. Among more than 8000 patients who had a diagnosis of HS (International Classification of Disease 10th revision code L73·2) and more than 100 patients
who were on biological therapy, we identified 58 patients with confirmed COVID‐19 (positive reverse‐transcriptase polymerase chain reaction) between 15 March and 25 May 2020. The majority of our patients with HS were female and of either Hispanic or African
American race/ethnicity. Rates of hospital and intensive care unit admission and death were not increased in our study sample when compared with the entire PHS population with confirmed COVID‐19 at that time. |
|
Uncertain growth model for the cumulative number of COVID-19 infections in
China |
Liu, Z |
Fuzzy Optimization and Decision Making |
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie |
This paper aims to depict cumulative numbers of COVID-19 infections in China using the growth model chosen by cross
validation. The residual plot does not look like a null plot, so we can not find a distribution function for the disturbance term that is close enough to the true frequency. Therefore, the disturbance term can not be characterized as random variables, and
stochastic regression analysis is invalid in this case. To better describe this pandemic automatically, this paper first employs uncertain growth models with the help of uncertain hypothesis tests to detect and modify outliers in data. The forecast value and
confidence interval for the cumulative number of COVID-19 infections in China are provided. |
|
Liu, ZM, Li, et al |
International Journal of Medical Sciences |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
We retrospectively reviewed the information of 1525 cases from the Leishenshan Hospital in Wuhan. Univariate and multivariate
Cox regression analyses were generated to explore the relationship between procalcitonin (PCT) level and the progression and prognosis of COVID-19. Univariate and multivariate logistic regression analyses were performed to explore the relationship between
disease severity in hospitalized patients and their PCT levels. Survival curves and the cumulative hazard function for COVID-19 progression were conducted in the two groups. To further detect the relationship between the computed tomography score and survival
days, curve-fitting analyses were performed. Patients in the elevated PCT group had a higher incidence of severe and critical severity conditions (P < 0.001), death, and higher computed tomography (CT) scores. There was an association between elevated PCT
levels and mortality in the univariate ((hazard ratio 1], 3.377; 95% confidence interval 2], 1.012-10.344; P = 0.033) and multivariate Cox regression analysis (HR, 4.933; 95% CI, 1.170-20.788; P = 0.030). Similarly, patients with elevated PCT were more likely
to have critically severe disease conditions in the univariate (odds ratio 2], 7.247; 95% CI, 3.559-14.757; P < 0.001) and multivariate logistic regression analysis (OR, 10.679; 95% CI, 4.562-25.000; P < 0.001). Kaplan-Meier curves showed poorer prognosis
for patients with elevated PCT (P = 0.024). The CT score 1 for patients with elevated PCT peaked at day 40 following the onset of symptoms then decreased gradually, while their total CT score was relatively stable. PCT level was shown as an independent risk
factor of in-hospital mortality among COVID-19 patients. |
|
|
Longo, M, Caruso, et al |
Diabetes research and clinical practice |
Public Health response| Interventions de santé publique |
Aims: This study aims at evaluating the metrics of glycemic control in people with type 1 diabetes using the hybrid
closed loop (HCL) system during the COVID-19 lockdown. Methods: This is a retrospective study of thirty adults with type 1 diabetes using HCL and followed with telemedicine at an Italian University Hospital. Data on metrics of glucose control were collected
at different times: two weeks before the lockdown (Time 0), first two weeks of lockdown (Time 1), last two weeks of lockdown (Time 2) and first two weeks after the lockdown (Time 3). The primary endpoint was the change in glucose management indicator (GMI)
across the different time points. Results: GMI did not worsen over time (Time 1 vs Time 3, 7% vs 6.9%, P < 0.05), whereas a reduction of mean glucose (P = 0.004) and indices of glucose variability was observed. Time in range (TIR) significantly increased (68.5%
vs 73.5%, P = 0.012), and time above range (TAR) level 2 (251–400 mg/dL) significantly decreased (P = 0.002). The improvement of TIR and glucose variability was mainly observed in participants < 35 years. Conclusions: Adults with type 1 diabetes using HCL
showed a significant improvement of most of the metrics of glucose control during the COVID-19 lockdown. © 2020 Elsevier B.V. |
|
|
Lopes, B, Bortolon, et al |
Psychiatry research |
Public Health response| Interventions de santé publique |
This study examines the impact of COVID-19 (in the early phase of the outbreak) on symptoms of psychosis, namely paranoia
and hallucinations. Three hundred and sixty-one people in the United Kingdom participated in a 2 (self-isolation vs. no self-isolation) x 2 (perceived COVID-19 symptomatology vs. no perceived COVID-19 symptomatology) x 2 (exposure to COVID-19 news vs. control)
experiment online. Participants completed measures of political trust, social network, fear of COVID-19, current paranoid thoughts, hallucinatory experiences and compulsive buying. Kruskal-Wallis results showed that employed people and students are more prone
to paranoia and hallucinatory experiences in response to COVID-19 news. A multigroup model showed a moderation effect of the news conditions - in the COVID-19 news condition, fear of COVID-19 and political trust significantly predict the variance of paranoia,
hallucinatory experiences and compulsive buying and these co-vary with each other but not in the control condition. In line with cognitive and social theories of paranoia, results suggest that negative affect and low political trust are linked to the presence
of paranoid thoughts and hallucinatory experiences and compulsive buying amid COVID-19. Digitized and Tailored Cognitive and Behavioral Therapy are proposed to address the psychiatric impact of COVID-19. © 2020 Elsevier B.V. |
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The more you know, the less you fear: Reflexive social work practices in times
of COVID-19 |
López Peláez, A, Marcuello-Servós, et al |
International Social Work |
Public Health response| Interventions de santé publique |
This study describes the results of a strategy to disseminate best social work practices during periods of social lockdown
in Spain. With the population in lockdown, the strategy was to design a series of innovative web seminars on both the subject and the procedures involved in social work, with the aim of sharing information and best practices to counter disinformation campaigns
on social media. The results show the growing demand – both by citizens in general and students and professionals in particular – for reliable information in the field of professional practice. |
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MeCas12a, a Highly Sensitive and Specific System for COVID-19 Detection |
Ma, P, Meng, et al |
Advanced Science |
Diagnostics / Pathogen detection| Diagnostics / Détection d'agents pathogènes |
Cas12a-based systems, which detect specific nucleic acids via collateral cleavage of reporter DNA, display huge potentials
for rapid diagnosis of infectious diseases. Here, the Manganese-enhanced Cas12a (MeCas12a) system is described, where manganese is used to increase the detection sensitivity up to 13-fold, enabling the detection of target RNAs as low as five copies. MeCas12a
is also highly specific, and is able to distinguish between single nucleotide polymorphisms (SNPs) differing by a single nucleotide. MeCas12a can detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in clinical samples and distinguish between
SARS-CoV-2 and Middle East respiratory syndrome coronavirus (MERS-CoV) RNA in simulated samples, thus offering an attractive alternative to other methods for the diagnosis of infectious diseases including COVID-19 and MERS. © 2020 The Authors. Published by
Wiley-VCH GmbH |
|
Ma, X, Wang, et al |
Personality and Individual Differences |
Public Health response| Interventions de santé publique |
To better understand human adjustments to this public health emergency and its underlying mechanism, the relationship
between perceived parental psychological control in emerging adults and individual's emotional reactivity to COVID-19 as well as the role of empathy was examined. Results revealed that parental psychological control conferred risks for individual's increased
negative emotional reactivity to this pandemic. Moreover, our findings shed light on personal distress as a mechanism through which parental psychological control induces negative emotional reactivities |
|
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Telehealth adoption among endocrinologists during the COVID-19 pandemic |
Madduri, S, Chowdhary, et al |
Endocrine Practice |
Healthcare Response | Réponse des soins de santé |
In this survey, we aimed to gauge the adoption of telehealth practices during the COVID-19 pandemic among endocrinologists
in the United States (U.S.). With the COVID-19 outbreak, more than two-fifths (44.2%) of participants switched to completely virtual visits, and an additional 44.2% switched to a majority of virtual visits, with some in-person visits in the outpatient setting.
Additionally, there was a significantly higher adoption rate of telehealth among endocrinologists younger than or equal to 40 years of age (P = .02) and among those who practiced in northeastern, midwestern, and the western geographic regions of the U.S. (P
= .04). |
|
Mækelæ, MJ, Reggev, et al |
Royal Society Open Science |
Public Health response| Interventions de santé publique |
Assessed how effective a range of restrictions were perceived, how severely they affected daily life, general distress
and paranoia during the early phase of the outbreak in Brazil, Colombia, Germany, Israel, Norway and USA. Most of the respondents rated the restrictions as effective. School closings were perceived as having the strongest effect on daily life. Participants
who believed their country reacted too mildly perceived the risk of contracting SARS-CoV-2 to be higher, were more worried and expressed reduced beliefs in the ability to control the outbreak. Relatedly, dissatisfaction with governmental reactions corresponded
with increased distress levels. |
|
|
Mahmoud, H, Ammar, et al |
Clinical Ophthalmology |
Clinical data| Données cliniques |
Assessed SARS-CoV-2 virus in conjunctival tears and secretions of positive confirmed COVID-19 patients. Tear and conjunctival
swabs were positive in 8 (28.57%) patients, while other patients’ swabs were negative (71.43%). Out of 10 patients with conjunctival manifestations, 3 patients had SARS-CoV-2 in their conjunctiva using (RT-PCR) test. Out of the 18 patients with no conjunctival
manifestations, 5 patients had positive SARS-CoV-2 in their conjunctiva using (RT-PCR) test. |
|
|
Mahmoudi, MR, Heydari, et al |
Alexandria Engineering Journal |
Epidemiology| Épidémiologie |
The number of patients with Covid-19 and the number of deaths due to this disease in France, Germany, Iran, Italy,
Spain, United Kingdom, and Unites States America are considered. The results indicated that there were extreme positive relations between the considered countries, based on the number of patients with Covid-19 and the number of deaths due to this disease.
The results indicated that, for the number of patients, the distribution of spreading in United States America and United Kingdom was similar to each other and differed from other countries. Also, for the number of deaths, the distribution of spreading in
Spain, Italy and Iran was similar to each other and differed from other countries. |
|
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Rheumatic Disease-Related Symptoms During the Height of the COVID-19 Pandemic |
Mancuso, CA, Duculan, et al |
HSS Journal |
Public Health response| Interventions de santé publique |
Identified COVID-19-related stressors that patients associated with worsening rheumatic disease symptoms. Of 112 patients
enrolled, 2 patients had SARS-CoV-2 infection. Patients reported that coping with challenges due to the pandemic both directly and indirectly worsened their rheumatic disease symptoms. Categories associated with direct effects were increased fatigue (i.e.,
from multitasking, physical work, and taking precautions to avoid infection) and worsening musculoskeletal and cognitive function. Categories associated with indirect effects were psychological worry (i.e., about contracting SARS-COV-2, altering medications,
impact on family, and impact on job and finances) and psychological stress (i.e., at work, at home, from non-routine family responsibilities, about uncertainty related to SARS-CoV-2, and from the media). |
|
Identification and control of SARS-CoV-2 epidemic model parameters |
Marinoschi, Gabriela |
arXiv |
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie Transmission
Public health interventions*| Interventions de santé publique |
We propose a mathematical model with five compartments for the SARS-CoV-2 transmission: susceptible S, undetected infected
asymptomatic A, undetected infected symptomatic I, confirmed positive and isolated L, and recovered R, for which we have a twofold objective. First, we formulate and solve an inverse problem focusing mainly on the identification of the values A0 and I0 of
the undetected asymptomatic and symptomatic individuals, at a time t0, by available measurements of the isolated and recovered individuals at two succeeding times, t0 and T>t0. Simultaneously, we identify the rate standing for the average number of individuals
infected in unit time by an infective symptomatic individual. Then, we propose a control problem aiming at controlling the infected classes by improving the actions in view of isolating as much as possible the populations A and I in the class L. These objectives
are formulated as minimization problems, the second one including a state constraint, which are treated by an optimal control technique. The existence of optimal controllers is proved and the first order necessary conditions of optimality are determined. For
the second problem, they are deduced by passing to the limit in the conditions of optimality calculated for an appropriately defined approximating problem. In this case, the dual system is singular and has a component in the space of measures. The discussion
of the asymptotic stability of the system done for the case when life immunity is gained reveals an asymptotic extinction of the disease, with a well determined reproduction number. |
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The psychology of the COVID-19 pandemic: A group-level perspective |
Marmarosh, CL, Forsyth, et al |
Group Dynamics |
Public Health response| Interventions de santé publique |
Applying group dynamic and group therapy theory and research, we explore why COVID-19 spread so rapidly. We also explore
how people cope with prolonged social isolation, distress, and social inequities, as well as how people deal with the psychological trauma of the disease. Researchers and theorists suggest that human beings are fundamentally social, and the need to gather
with others is extremely important, especially during times of distress. The need to belong as well as the importance of reducing loneliness during uncertain times often encourages people to connect, despite recommendations to remain socially distant. |
|
Martinotti, G, Alessi, et al |
Frontiers in Psychiatry |
Public Health response| Interventions de santé publique |
Evaluated the impact that the COVID-19 pandemic, and the relative containment measures, have had on a real-life sample
of patients suffering from substance use disorders (SUDs) and/or behavioral addictions. Found moderate rates of depression (22.9%), anxiety (30.1%), irritability (31.6%), and post-traumatic stress (5.4%) symptoms. Psychopathological burden was globally higher
among residential patients. Reported levels of craving were generally low. |
|
|
Martins, CM, Gomes, et al |
Texto e Contexto Enfermagem |
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie |
Produced a predictive model for the incidence of COVID-19 cases, severity and deaths in Ponta Grossa, state of Paraná.
Provides COVID-19 projections for a municipality that is not a large capital. The SIR model estimated that, in the best scenario, the peak period will be around 120 days after the first case (between July 11, 2020 and July 25, 2020), estimated R0 will be 1.07
and will infect 0.23% of the population. In the worst scenario, peak period will involve 4,375 (95% CI; 4156-4594) cases and 825 (95% CI; 700-950) cases in the best scenario. Most cases and hospital admissions will involve patients aged 20 to 39 years, the
number of deaths will be higher among the elderly and more pronounced among patients aged ≥80 years. |
|
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Smart „plan b” – in face with disruption of supply chains in 2020 |
Marzantowicz, Ł, Nowicka, et al |
Logforum |
Economics | Économie |
Identified supply chain resilience in terms of risk management during the beginning of the COVID-19/SARS-CoV-2 pandemic
spread in 2020. The results obtained show that the first phase of pandemic spread unexpectedly strongly and impacted on disruption in the supply chains. Closed borders, sanitary and administrative restrictions have leaded to transport delays, additionally
the lower number of orders was noted causing many disruptions in the further flow of the goods. Surprisingly the disruption happened even when managers synergistically cooperate and share information among partners. |
|
Masiá, M, Fernández-González, et al |
EBioMedicine |
Clinical data| Données cliniques Therapeutics| Thérapeutique |
Evaluated the impact of interleukin (IL)-6 blockade with tocilizumab on SARS-CoV-2 viral kinetics and the antibody
response in patients with COVID-19. 138 patients with confirmed infection were included; 76 (55%) underwent IL-6 blockade. Median initial SOFA and SARS-CoV-2 viral load were significantly higher among anti-IL-6 users. Patients under IL-6 blockade showed delayed
viral clearance in the Kaplan-Meier curves, but an adjusted propensity score matching model did not demonstrate a significant relationship of IL-6 blockade with viral clearance. Patients under the IL-6 blocker showed shorter median time to seropositivity,
higher peak antibody titers, and higher cumulative proportion of seropositivity. Results suggest that in patients infected with SARS-CoV-2, IL-6 blockade does not impair the viral specific antibody responses. Although a delayed viral clearance was observed,
it was driven by a higher initial viral load. |
|
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Emotional analysis using twitter data during pandemic situation: Covid-19 |
Mathur, A, Kubde, et al |
|
Public Health response| Interventions de santé publique |
During the crisis situation caused due to COVID-19 disease, managing mental health and psychological well-being is
as important as physical health of people. As web based life is broadly utilized by individuals to communicate their feeling and supposition, our framework utilizes Twitter information posted by individuals during this emergency circumstance to dissect the
feelings of individuals. For processing the cleaned data NRC Word-Emotion Association Lexicon (have aka EmoLex) is used. NRC Word-Emotion Association Lexicon is a list of English with real-valued scores of intensity for eight basic emotion words ns (anger,
anticipation, disgust, fear, joy, sadness, surprise, and trust). The text content of tweeter dataset created by fetching tweets across the world have classified into basic emotions like anger, anticipation, disgust, fear, joy, sadness, surprise and trust.
This analysis can be used by authorities to understand the mental health of the people and can take necessary measures to decide on policies to fight against coronavirus which is affecting the social well-being as well as economy of the whole world. © 2020
IEEE. |
|
Matos, ADR, Motta, et al |
Memorias do Instituto Oswaldo Cruz |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
Coronavirus disease 2019 (COVID-19) surveillance, in Brazil, initiated shortly after its description, in China. Our
aim was to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and additional pathogens in samples from the initial phase of the outbreak in Brazil, from late February to late March. From 707 samples analysed, 29 (4.1%) were SARS-CoV-2 positive.
Fever and cough were their most prevalent symptoms. Co-detection of rhinovirus was observed in 2 (6.9%) cases. Additional pathogens were identified in 66.1% of the SARS-CoV-2 negative cases, mainly rhinovirus and inf luenza A(H1N1) pdm09. Thus, we emphasise
the importance of differential diagnosis in COVID-19 suspected cases. © 2020, Fundacao Oswaldo Cruz. All rights reserved. |
|
|
Survey of the current status of subclinical coronavirus disease 2019 (COVID-19) |
Matsuba, I, Hatori, et al |
Journal of Infection and Chemotherapy |
Epidemiology| Épidémiologie Immunology | Immunologie |
Investigated relationships between subclinical COVID-19 and background factors. The 39 subjects (2.4%) were found to
be IgG antibody-positive: 29 in the patient group (2.9%), 10 in the doctor/nurse group (2.0%), and 0 in the control group. After adjustment for age, sex, and the antibody prevalence in the control group, antibody prevalence was 2.7% in the patient group and
2.1% in the doctor/nurse group. There was no significant difference between the antibody-positive subjects and the antibody-negative subjects in any background factors investigated. These data suggest that subclinical infections are occurring more frequently
than expected. |
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32920162; The effect of liver test abnormalities on the prognosis of COVID-19 |
Medetalibeyoglu, A, Catma, et al |
Annals of Hepatology |
Clinical data| Données cliniques |
Investigated the relationship between the liver enzymes on admission (AST, ALT, ALP, GGT) and severity of COVID-19.
We evaluated course of disease, hospital stay, liver damage and mortality. Mortality rate and need for intensive care unit were statistically significant in subjects that had high ALT–AST levels during their admission to the hospital (p = 0.001). According
to the ROC analysis AST/ALT ratio was a good marker of mortality risk (AUC = 0.713: p = 0.001) and expected probability of intensive care unit admission (AUC = 0.636: p = 0.001). R ratio, which was used to evaluate prognosis, showed a poor prognosis rate of
26.5% in the cholestatic injury group, 36.1% in the mixed pattern group and 30% in the hepato-cellular injury group (p 0.001). |
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Migration and reverse migration: Gulf-Malayalees’ perceptions during the Covid-19 pandemic |
Menon, DV, Vadakepat, et al |
South Asian Diaspora |
Public Health response| Interventions de santé publique |
Through a means-end approach, this study reviews respondents’ attributes, consequences, and values at the time of migration
and compares it with their perceptions during the sudden Covid-19 related reverse migration from the United Arab Emirates. |
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Generating Realistic COVID19 X-rays with a Mean Teacher + Transfer Learning GAN |
Menon, Sumeet, Galita, et al |
arXiv |
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection
d'agents pathogènes |
We present a novel Mean Teacher + Transfer GAN (MTT-GAN) that generates COVID19 chest X-ray images of high quality.
In order to create a more accurate GAN, we employ transfer learning from the Kaggle Pneumonia X-Ray dataset, a highly relevant data source orders of magnitude larger than public COVID19 datasets. Furthermore, we employ the Mean Teacher algorithm as a constraint
to improve stability of training. Our qualitative analysis shows that the MTT-GAN generates X-ray images that are greatly superior to a baseline GAN and visually comparable to real X-rays. Quantitative analysis shows that MTT-GAN greatly improves the accuracy
of both a binary COVID19 classifier as well as a multi-class Pneumonia classifier as compared to a baseline GAN. |
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32889039; Stress and Symptom Burden in Oncology Patients During the COVID-19 Pandemic |
Miaskowski, C, Paul, et al |
Journal of pain and symptom management |
Public Health response| Interventions de santé publique |
Evaluated differences in demographic and clinical characteristics, levels of social isolation and loneliness, and the
occurrence and severity of common symptoms between oncology patients with low vs. high levels of COVID-19 and cancer-related stress. Of the 187 patients in this study, 31.6% were categorized in the stressed group (Impact of Event Scale—Revised score of ≥24]).
Stressed group's Impact of Event Scale—Revised score exceeds previous benchmarks in oncology patients and equates with probable post-traumatic stress disorder. In this stressed group, patients reported occurrence rates for depression (71.2%), anxiety (78.0%),
sleep disturbance (78.0%), evening fatigue (55.9%), cognitive impairment (91.5%), and pain (75.9%). Symptom severity scores equate with clinically meaningful levels for each symptom. |
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Association between Covid-19 and Pulmonary Embolism (AC-19-PE study) |
Miró, Ò, Llorens, et al |
Thrombosis research |
Clinical data| Données cliniques |
Designed the AC-19-PE (Association between COVID-19 and Pulmonary Embolism) study to further explore this hypothesis
by determining whether PE is more frequently suspected by emergency physicians and whether PE is more frequently diagnosed during the COVID pandemic and in COVID-affected patients. The frequency of PE in COVID patients attending the ED is 6.64‰ (95%CI=5.06–8.56‰),
which was more than 7-fold higher than that in the non-COVID ED population. This relatively high rate suggests that during the COVID period, the ED population comprised more patients with suspected and diagnosed PE, due, in part, to a higher suspicion by emergency
physicians and also to fewer ED visits for other complaints (due to lockdown measures). Further PE was only counted for study purposes if a CTPA was performed in the ED. During the COVID-19 pandemic, emergency physicians had a lower threshold for ordering
CTPA (OR = 2.39), although CTPA positivity for PE did not differ between periods (OR = 1.04), confirming that SARS-COV-2 is not associated with a higher incidence of PE among high risk patients |
|
Mirza, MU, Ahmad, et al |
Computational Biology and Chemistry |
Coronavirology| Coronavirologie Therapeutics| Thérapeutique |
Human ubiquitin carboxyl-terminal hydrolase-2 (USP2) inhibitors, such as thiopurine analogs, have been reported to
inhibit SARS-CoV papain-like proteases (PLpro). The PLpro have significant functional implications in the innate immune response during SARS-CoV-2 infection and considered an important antiviral target. Both proteases share strikingly similar USP fold with
right-handed thumb–palm–fingers structural scaffold and conserved catalytic triad Cys-His-Asp/Asn. In this urgency situation of COVID-19 outbreak, there is a lack of in-vitro facilities readily available to test SARS-CoV-2 inhibitors in whole-cell assays.
Therefore, we adopted an alternate route to identify potential USP2 inhibitor through integrated in-silico efforts. After an extensive virtual screening protocol, the best compounds were selected and tested. The compound Z93 showed significant IC50 value against
Jurkat (9.67 μM) and MOTL-4 cells (11.8 μM). The binding mode of Z93 was extensively analyzed through molecular docking, followed by MD simulations, and molecular interactions were compared with SARS-CoV-2. The relative binding poses of Z93 fitted well in
the binding site of both proteases and showed consensus π-π stacking and H-bond interactions with histidine and aspartate/asparagine residues of the catalytic triad. These results led us to speculate that compound Z93 might be the first potential chemical
lead against SARS-CoV-2 PLpro, which warrants in-vitro evaluations. © 2020 Elsevier Ltd |
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Mohamed, YG, Mohamud, et al |
Egyptian Journal of Radiology and Nuclear Medicine |
Clinical data| Données cliniques |
Demonstrate the clinical and radiological characteristics of COVID-19 patients in Somalia from 20 March 2020 to 20
April 2020. The majority (59.3%) of COVID-19-infected patients had no obvious history of exposure to infected patients. The participants of our study mostly presented with dry cough 24 (88.9%) patients, fever 19 (70.4%), myalgia 18 (66.6%), and sore throat
16 (59.3%). Twenty-five of 27 patients had abnormal chest CT, while 2 (7.4%) patients had normal chest CT. The most common patterns of abnormality seen on chest CT in patients with COVID-19 were ground-glass opacity (GGO) 74.1%, crazy paving pattern 18.5%,
consolidation 14.8%, and mixed GCO 11.1%. Also, the most common predominant lesion distributions were bilateral lung involvement (88.9%), peripheral distribution (77.8%), and lower lung predominance (63%). |
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Mohan, A, Tiwari, et al |
The Indian journal of medical research |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
The present study was aimed to describe the clinico-demographic characteristics and in-hospital outcomes of a group
of COVID-19 patients in north India. Data of 144 patients with COVID-19 were recorded and analyzed. The mean age of the patients was 40.1±13.1 yr, with 93.1 per cent males, and included 10 (6.9%) foreign nationals. Domestic travel to or from affected States
(77.1%) and close contact with COVID-19 patients in congregations (82.6%) constituted the most commonly documented exposure. Nine (6.3%) patients were smokers, with a median smoking index of 200. Comorbidities were present in 23 (15.9%) patients, of which
diabetes mellitus (n=16; 11.1%) was the most common. A significant proportion of patients had no symptoms (n=64; 44.4%); among the symptomatic, cough (34.7%) was the most common symptom followed by fever (17.4%) and nasal symptoms (2.15%). Majority of the
patients were managed with supportive treatment with hydroxychloroquine and azithromycin given on a case-to-case basis. Only five (3.5%) patients required oxygen supplementation, four (2.8%) patients had severe disease requiring intensive care, one required
mechanical ventilation and mortality occurred in two (1.4%) patients. The time to reverse transcription-polymerase chain reaction (RT-PCR) negativity was 16-18 days. |
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Cities under pressure: Strategies and tools to face climate change and pandemic |
Moraci, F, Errigo, et al |
Sustainability (Switzerland) |
Public Health response| Interventions de santé publique |
Besides highlighting the characteristics of climate change and the ongoing pandemic, this study focuses on the analysis
of the main effects and consequences that these phenomena have produced on the city and the vulnerabilities of the urban system. To understand how these events have impacted the urban environment, directly and indirectly, this research undertakes to define
some specific indicators capable of comparing the phenomena and assessing their repercussions. The Methodology is based on the following focal points: on the analysis of the urban shocks that have affected the cities in the last decade, on the comparison between
contemporary survey data and those relating to historical trends, on the definition of the main urban sectors particularly affected by the onset of urban shocks, and on the definition of strategies, actions, and tools deemed to be effective in the implementation
of a post-pandemic and climate-proof city. |
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Muehlemann, S, Pfeifer, et al |
Empirical Research in Vocational Education and Training |
Economics | Économie |
The current coronavirus crisis will have a strong and negative impact on the German economy. We expect a downward shift
in firm demand for apprentices and consequently also a decrease in the equilibrium number of apprenticeship contracts. To assess the impact of changes in business cycle expectations, we analyze German data on the apprenticeship market at the state-level and
at the occupation-level within states from 2007 to 2019. We apply first-differences regressions to account for unobserved heterogeneity across states and occupations, allowing us to identify the association between changes in two popular measures of business
cycle expectations (the ifo Business Climate Index and the ifo Employment Barometer) and subsequent changes in the demand for apprentices, the number of new apprenticeship contracts, unfilled vacancies and unsuccessful applicants. We find that the German apprenticeship
market prior to the current crisis can be characterized by excess demand for apprentices (although there are matching problems in some states, with both a high share of unfilled vacancies and a high share of unsuccessful applicants). Taking into account the
most recent data on business cycle expectations up to June 2020, we estimate that the coronavirus-related decrease in firms’ expectations about the business cycle can be associated with a predicted 8% decrease in firm demand for apprentices and a 6% decrease
in the number of new apprenticeship positions in Germany compared to 2019 (− 30,000 apprenticeship contracts; 95% confidence interval: ± 8000). |
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COVID-19 Disease and Hypercoagulability Leading to Acute Ischemic Stroke |
Mullaguri, N, Hepburn, et al |
Neurohospitalist |
Clinical data| Données cliniques |
We present 3 cases of patients with COVID-19 disease who presented with varying degrees of vascular thrombosis. Cases:
Cases 1 and 2 presented as cerebral ischemic strokes without respiratory failure. Given their exposure risks, they were both tested for COVID-19 disease. Case 2 ultimately developed respiratory failure and pulmonary embolism. Cases 2 and 3 were found to have
simultaneous arterial and venous thromboembolism (ischemic stroke and pulmonary embolism) as well as positive antiphospholipid antibodies. Our case series highlight the presence of hypercoagulability as an important mechanism in patients with COVID-19 disease
with and without respiratory failure. |
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Murhekar, MV, Bhatnagar, et al |
The Indian journal of medical research |
Epidemiology| Épidémiologie Immunology | Immunologie |
We report the findings of the first round of a national serosurvey, conducted to estimate the seroprevalence of SARS-CoV-2
infection among adult population of India. From May 11 to June 4, 2020, a randomly sampled, community-based survey was conducted in 700 villages/wards, selected from the 70 districts of the 21 States of India. Population-weighted seroprevalence after adjusting
for test performance was 0.73 per cent 95% CI: 0.34-1.13. Males, living in urban slums and occupation with high risk of exposure to potentially infected persons were associated with seropositivity. A cumulative 6,468,388 adult infections (95% CI: 3,829,029-11,199,423)
were estimated in India by the early May. The overall ICR was between 81.6 (95% CI: 48.3-141.4) and 130.1 (95% CI: 77.0-225.2) with May 11 and May 3, 2020 as plausible reference points for reported cases. The IFR in the surveyed districts from high stratum,
where death reporting was more robust, was 11.72 (95% CI: 7.21-19.19) to 15.04 (9.26-24.62) per 10,000 adults, using May 24 and June 1, 2020 as plausible reference points for reported deaths. Seroprevalence of SARS-CoV-2 was low among the adult population
in India around the beginning of May 2020. |
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Mutz, M |
European Societies |
Public Health response| Interventions de santé publique |
Based on representative survey data from Germany (≥14 years, N = 1001), the paper addresses the changes in sport and
exercise activities in the pandemic situation and their association with emotional well-being. Findings show a reduced level of emotional well-being in the German population during the Covid-19 pandemic. In particular, those individuals who stopped or considerably
reduced their sport and exercise activities during the pandemic report a significant decline of well-being compared to the time before the pandemic. Individuals, who reduced sport and exercise due to external constraints, reported the largest decline in well-being.
In contrast, the small group of individuals who intensified their sporting activities during the pandemic stands out with the most positive well-being levels. Irrespective of sport and exercise adaptations, findings additionally show that females report a
steeper decline in well-being during the crisis compared to men. |
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|
Nabian, MH, Vosoughi, et al |
Injury |
Healthcare Response | Réponse des soins de santé |
In the current study, we intend to identify the possible epidemiological shift in pediatric fracture patterns, by comparing
the data from ‘COVID-19 era’ and the mean data from the past 2 years. Altogether 117 of the 288 trauma children (40.62%) had a fractured bone (145 fractures). Patients were mostly boys, with a mean age of 9.87 years (SD=5.27). The three most common fracture
types in children included distal radius, mid-forearm and humeral supracondylar fractures. Compared to non-COVID era, the number of pediatric trauma admissions dropped from 589 to 288. No significant change happened in the mean age, male/female ratio and percentage
of motor vehicle accidents. Proportion of proximal humeral, proximal forearm, carpal, and hand fractures declined. The number of open fractures significantly dropped (from 12 to 2). |
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Impact of COVID-19 containment measures on air pollution in California |
Naeger, AR, Murphy, et al |
Aerosol and Air Quality Research |
Public health interventions*| Interventions de santé publique |
This study used space-and ground-based sensors in conjunction meteorological and traffic information to evaluate the
impact of the COVID-19 containment measures on air pollution in California by comparing data from March–April 2020 to the similar period in 2019. Altogether, the space-and ground-based observations provide strong evidence that the containment measures led
to NO2 reductions of around 35% in Los Angeles and Fresno and 25% in San Francisco and Bakersfield relative to 2019, along with decreases in PM2.5 and improved air quality at the surface. |
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Narinx, N, Smismans, et al |
Emergency Radiology |
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection
d'agents pathogènes Healthcare Response | Réponse des soins de santé |
Diagnostic value of point-of-care lung ultrasound (POCUS) in detection of coronavirus disease (COVID-19) in an emergency
setting is currently unclear. In this study, we aimed to compare diagnostic performance, in terms of sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy, of POCUS lung, chest CT, and RT-PCR for clinically
suspected COVID-19 infections in patients submitting to the emergency room (ER). This retrospective study enrolled 93 patients with a suspected COVID-19 infection, admitted to the ER between March 28th and April 20th, 2020. Test subjects showed one or more
symptoms of an acute respiratory infection, for which consequent COVID-19 testing was achieved using POCUS lung, chest CT, and RT-PCR. CT images were analyzed by 2 radiologists blinded to RT-PCR results. POCUS lung was performed by three emergency medical
doctors, and reports were analyzed by the researcher, blinded to clinical information, US imaging, CT, and RT-PCR test results. Results: Compared with RT-PCR, POCUS lung demonstrated outstanding sensitivity and NPV (93.3% and 94.1% respectively) while showing
poor values for specificity, PPV, and accuracy (21.3%, 19.2%, and 33.3% respectively). In contrast, similar inquiries using chest CT as index test, excellent sensitivity, specificity, NPV, and accuracy (80.0%, 86.7%, 95.6%, and 85.6%, respectively) were reported,
beside a moderate value for PPV (54.5%). |
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Nascimento, VAD, Corado, et al |
Memorias do Instituto Oswaldo Cruz |
Coronavirology| Coronavirologie |
We report the complete genome sequencing and genetic characterisation of a SARS-CoV-2 detected in Manaus, Amazonas,
Brazil, and the protocol we designed to generate high-quality SARS-CoV-2 full genome data. The isolate was obtained from an asymptomatic carrier returning from Madrid, Spain. Nucleotide sequence analysis showed a total of nine mutations in comparison with
the original human case in Wuhan, China, and support this case as belonging to the recently proposed lineage A.2. Phylogeographic analysis further confirmed the likely European origin of this case. |
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Natalello, G, De Luca, et al |
Microvascular research |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
Our aim was to assess microvasculature through nailfold videocapillaroscopy (NVC) in COVID-19 patients. We performed
NVC in patients with a confirmed diagnosis of COVID-19 pneumonia. Elementary alterations were reported for each finger according to a semi-quantitative score. Capillary density, number of enlarged and giant capillaries, number of micro-hemorrhages and micro-thrombosis
(NEMO score) were registered. We enrolled 82 patients (mean age 58.8 ± 13.2 years, male 68.3%) of whom 28 during the hospitalization and 54 after recovery and hospital discharge. At NVC examination we found abnormalities classifiable as non-specific pattern
in 53 patients (64.6%). Common abnormalities were pericapillary edema (80.5%), enlarged capillaries (61.0%), sludge flow (53.7%), meandering capillaries and reduced capillary density (50.0%). No pictures suggestive of scleroderma pattern have been observed.
Acute COVID-19 patients, compared to recovered patients, showed a higher prevalence of hemosiderin deposits as a result of micro-hemorrhages (P = .027) and micro-thrombosis (P < .016), sludge flow (P = .001), and pericapillary edema (P < .001), while recovered
patients showed a higher prevalence of enlarged capillaries (P < .001), loss of capillaries (P = .002), meandering capillaries (P < .001), and empty dermal papillae (P = .006). Currently ill and recovered subjects are characterized by a different distribution
of elementary capillaroscopic alterations, resembling acute and post-acute microvascular damage. |
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Dynamically evolving novel overlapping gene as a factor in the SARS-CoV-2
pandemic |
Nelson, ChaseW, Ardern, et al |
bioRxiv |
Coronavirology| Coronavirologie zoonoses |
Understanding the emergence of novel viruses requires an accurate and comprehensive annotation of their genomes. Overlapping
genes (OLGs) are common in viruses and have been associated with pandemics, but are still widely overlooked. We identify and characterize ORF3d, a novel OLG in SARS-CoV-2 that is also present in Guangxi pangolin-CoVs but not other closely related pangolin-CoVs
or bat-CoVs. We then document evidence of ORF3d translation, characterize its protein sequence, and conduct an evolutionary analysis at three levels: between taxa (21 members of Severe acute respiratory syndrome-related coronavirus), between human hosts (3978
SARS-CoV-2 consensus sequences), and within human hosts (401 deeply sequenced SARS-CoV-2 samples). ORF3d has been independently identified and shown to elicit a strong antibody response in COVID-19 patients. However, it has been misclassified as the unrelated
gene ORF3b, leading to confusion. Our results liken ORF3d to other accessory genes in emerging viruses and highlight the importance of OLGs.Competing Interest StatementThe authors have declared no competing interest. |
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Predictors of Social Distancing and Mask-Wearing Behavior: Panel Survey in Seven U.S. States |
Nikolov, Plamen, Pape, et al |
arXiv |
Public Health response| Interventions de santé publique |
This paper presents preliminary summary results from a longitudinal study of participants in seven U.S. states during
the COVID-19 pandemic. In addition to standard socio-economic characteristics, we collect data on various economic preference parameters: time, risk, and social preferences, and risk perception biases. We pay special attention to predictors that are both important
drivers of social distancing and are potentially malleable and susceptible to policy levers. We note three important findings: (1) demographic characteristics exert the largest influence on social distancing measures and mask-wearing, (2) we show that individual
risk perception and cognitive biases exert a critical role in influencing the decision to adopt social distancing measures, (3) we identify important demographic groups that are most susceptible to changing their social distancing behaviors. These findings
can help inform the design of policy interventions regarding targeting specific demographic groups, which can help reduce the transmission speed of the COVID-19 virus. |
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Nivette, A, Ribeaud, et al |
Social Science and Medicine |
Public Health response| Interventions de santé publique |
This paper leverages a prospective-longitudinal cohort study with data before and during the pandemic to describe patterns
of non-compliance with COVID- 19 related public health measures in young adults and to identify which characteristics increase the risk of non-compliance. Data came from an ongoing cohort study in Zurich, Switzerland (n=737). Non-compliance, especially with
hygiene-related measures, was more prevalent in males, and in individuals with higher education, higher SES, and a nonmigrant background. Non-compliance was higher in young adults who had previously scored high on indicators of “antisocial potential,” including
low acceptance of moral rules, pre-pandemic legal cynicism, low shame/guilt, low self-control, engagement in delinquent behaviors, and association with delinquent peers. Young adults with low trust, including in the government's measures for fighting the virus,
also complied less. |
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Novak, P |
eNeurologicalSci |
Clinical data| Données cliniques |
This report describes a post COVID-19 patient who developed chronic fatigue, orthostatic dizziness and brain fog consistent
with orthostatic hypoperfusion syndrome (OCHOS), a form of orthostatic intolerance, and painful small fiber neuropathy (SFN). |
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32773420; Transcriptome & viral growth analysis of SARS-CoV-2-infected vero CCL-81 cells |
Nyayanit, DA, Sarkale, et al |
Indian Journal of Medical Research, Supplement |
Coronavirology| Coronavirologie |
This study was undertaken to understand the transcription pattern of the SARS-CoV-2 genes in the Vero CCL-81 cells
during the course of infection. In the inital six hours post-infection, the copy numbers of E and RdRp-2 genes were approximately constant, which raised 10 log-fold and continued to increase till the 12 h post-infection (hpi). The TCID50 was observed in the
supernatant after 7 hpi, indicating the release of the viral progeny. ORF8 and ORF7a, along with the nucleocapsid transcript, were found to express at higher levels. The findings indicated that ORF8 and ORF7b gene transcripts were expressed in higher amounts
indicating their essential role in viral replication. Future studies need to be conducted to explore their role in the SARS-CoV-2 replication. |
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Nyayanit, DA, Yadav, et al |
Indian Journal of Medical Research, Supplement |
Coronavirology| Coronavirologie |
The present study looked at quasispecies present in SARS-CoV-2 clinical samples in India, using next-generation sequencing
data from Italian samples for comparison. Two different types of SARS-CoV-2 strains are classified depending on the nucleotide present at genomic position (GP) 8782 (gene: ORF1ab) and 28144 (gene: ORF8). The nucleotide change in the GP 8782 is a synonymous
nucleotide substitution, whereas the GP 28144 has a non-synonymous nucleotide substitution. The proportion of synonymous and non-synonymous nucleotide polymorphisms varied between Indian samples and Italian samples, highlighting the need for surveillance sequencing
for SARS-CoV-2 quasispecies. |
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Therapeutic strategy for severe COVID-19 pneumonia from clinical experience |
Ogawa, F, Kato, et al |
European Journal of Inflammation |
Clinical data| Données cliniques |
In this case series, a therapeutic strategy was initially developed based on previous treatment methods used for the
treatment of SARS and MERS in the absence of treatment options for COVID-19 due to a lack of information. During the search for a potential treatment, clinical findings were obtained from patients with severe COVID-19, and one therapeutic strategy was established.
This therapeutic strategy was then applied to severe COVID-19 patients. In addition, we can require some interesting clinical features and characteristics of COVID-19 from blood analysis and physical findings. Here, we reported on the clinical features and
characteristics of a therapeutic strategy for the treatment of severe COVID-19 pneumonia at our institution. |
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Oussalah, A, Gleye, et al |
EClinicalMedicine |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
Using a retrospective, longitudinal cohort study design on consecutive patients with severe COVID-19, we used an extensive
biochemical dataset of serial data and time-series design to estimate the occurrence of organ dysfunction and the severity of the inflammatory reaction and their association with acute respiratory failure (ARF) and death. On the 162 studied patients, 1151
biochemical explorations were carried out for up to 59 biochemical markers, totaling 15,260 biochemical values. The spectrum of biochemical abnormalities and their kinetics were consistent with a multi-organ involvement, including lung, kidney, heart, liver,
muscle, and pancreas, along with a severe inflammatory syndrome. The proportion of patients who developed an acute kidney injury (AKI) stage 3, increased significantly during follow-up (0·9%, day 0; 21·4%, day 14; P250 iterations), only CRP >90 mg/L (odds
ratio OR] 6·87, 95% CI, 2·36–20·01) and urea nitrogen >0·36 g/L (OR 3·91, 95% CI, 1·15–13·29) were independently associated with the risk of ARF. Urea nitrogen >0·42 g/L was the only marker associated with the risk of COVID-19 related death. |
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Padhi, S, Suvankar, et al |
International immunopharmacology |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
In the present study, we hypothesized that vitamin D deficiency would be associated with the SARS-CoV-2 infection rate
and mortality in the Indian population. An inverse correlation was observed between the mean level of 25(OH)D and SARS-CoV-2 infection rate (r = −0.43, p = 0.02) and mortality rate (r = −0.42, p = 0.02). The present observational study revealed an association
of vitamin D with SARS-CoV-2 infection and related mortality. Further studies are required to validate our observations. |
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Analysis and numerical simulation of novel coronavirus (COVID-19) model with Mittag-Leffler Kernel |
Padmavathi, V, Prakash, et al |
Mathematical Methods in the Applied Sciences |
Modelling/ prediction| Modélisation/prédiction Public health interventions*| Interventions
de santé publique |
Every now and then, there has been natural or man-made calamities. Such adversities instigate various institutions
to find solutions for them. The current study attempts to explore the disaster caused by the micro enemy called coronavirus for the past few months and aims at finding the solution for the system of nonlinear ordinary differential equations to which q−homotopy
analysis transform method (q−HATM) has been applied to arrive at effective results. In this paper, there are eight nonlinear ordinary differential equations considered and to solve them the advanced fractional operator Atangana-Baleanu (AB) fractional derivative
has been applied to produce better understanding. The outcomes have been presented in terms of plots. Ultimately, the present study assists in examining the real-world models and aids in predicting their behavior corresponding to the parameters considered
in the models. © 2020 John Wiley & Sons, Ltd. |
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Modeling the coronavirus disease 2019 incubation period: Impact on quarantine policy |
Pak, D, Langohr, et al |
Mathematics |
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie Public health
interventions*| Interventions de santé publique |
The incubation period of coronavirus disease 2019 (COVID-19) is not always observed exactly due to uncertain onset
times of infection and disease symptoms. In this paper, we demonstrate how to estimate the distribution of incubation and its association with patient demographic factors when the exact dates of infection and symptoms' onset may not be observed. The findings
from analysis of the confirmed COVID-19 cases indicate that age could be associated with the incubation period, and an age-specific quarantine policy might be more efficient than a unified one in confining COVID-19. © 2020 by the authors. |
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Park, SY, Choi, et al |
Osong Public Health and Research Perspectives |
Epidemiology| Épidémiologie Transmission Healthcare Response | Réponse des soins de
santé |
This study describes the epidemiological characteristics of coronavirus disease 2019 (COVID-19) based on reported cases
from long-term care facilities. As of April 20th, 2020, 3 long-term care facilities in a metropolitan area of South Korea had reported cases of COVID-19. These facilities' employees were presumed to be the sources of infection. There were 2 nursing hospitals
that did not report any additional cases. One nursing home had a total of 25 cases, with an attack rate of 51.4% (95% CI 35.6-67.0), and a fatality rate of 38.9% (95% CI 20.3-61.4) among residents. The results from this study suggest that early detection and
maintenance of infection control minimizes the risk of rapid transmission. © 2020 Korea Centers for Disease Control and Prevention. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
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Predicting COVID-19 in very large countries: the case of Brazil |
Parro, Vanderlei, Lafetá, et al |
Research Square prepub |
Modelling/ prediction| Modélisation/prédiction Transmission |
This work presents a new proposal for estimating health system use for COVID-19 cases, as well as a methodology for
using the model in the real world. The estimate was obtained by modifying the dynamic model known as Susceptible, Infected, Removed and Dead (SIRD), including a parameter to model not all cases but only the health system dynamics. The proposed model and the
respective tuned parameters were validated considering the data available for the 26 Brazilian states, demonstrating strong adherence in most cases and allowing the estimation of an epidemic model for the whole of Brazil, which was obtained via the linear
combination of the models for each state. In addition to the effective use of the health system, the incidence rate and removal rate were analysed, as was the reproduction rate: baseline R0 and effective Rt. In the specific case of Brazil, the states that
make up the federation have autonomy in decision making, which increases the complexity of the analysis of the evolution of the pandemic. With the proposed global model, the method used to tune the parameters and the available results, there was heterogeneity
in the dynamics observed for each state, which is compatible with some characteristics of the real-world scenario. |
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Impact on mental health due to covid-19 pandemic: Cross-sectional study in portugal and brazil |
Passos, L, Prazeres, et al |
International Journal of Environmental Research and Public Health |
Public Health response| Interventions de santé publique |
This cross-sectional study aimed to describe the mental health status of the general adult population in Portugal and
Brazil during the COVID-19 pandemic and analyze the differences between the two countries. Five hundred and fifty people answered the questionnaire (435 women). The median age was 38 (Q1, Q3: 30, 47) years, 52.5% resided in Brazil and 47.5% in Portugal. The
prevalence of anxiety was 71.3% (mild anxiety was present in 43.1%), the prevalence of depression was 24.7% and 23.8% of the sample had both depression and anxiety. Isolation was a significant factor for depression but not for anxiety. Well-being was below
average. Mental illness was considerably higher than pre-COVID-19 levels. |
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In-flight transmission of COVID-19 on flights to Greece: An epidemiological analysis |
Pavli, A, Smeti, et al |
Travel Medicine and Infectious Disease |
Epidemiology| Épidémiologie Transmission |
We present 5 cases of probable in-flight transmission in Greece. We studied international passengers arriving to or
departing from Greece from February 26 through March 9, 2020. Contact tracing extended up to 4 days before the onset of symptoms and focused on close contacts. Close contacts were defined as persons sitting within a distance of 15 min, including passengers
seated two seats around the index case and all crew members and persons who had close contact with the index case. Results: We investigated 18 international flights with 2224 passengers and 110 crew members. Main countries of departure included Northern Italy,
Israel and the United Kingdom. In accordance with the national surveillance investigation, in these flights there were 21 index cases and 891 contact traced cases. Six index cases were symptomatic during the flight. Of the 891 contact traced cases, 4 passengers
and 1 crew member developed laboratory-confirmed infection (3 with COVID-19 and 2 with asymptomatic infection); they travelled on the same flight with two COVID-19 cases. |
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Pavoni, V, Gianesello, et al |
Thrombosis research |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
Background: Critically ill COVID-19 patients have a clear pattern of inflammation and hypercoagulable state. The main
aim of the study was to evaluate the outcome of severe COVID-19 patients basing on prothrombotic risk factors (i.e. D-dimer). We also evaluated the impact of different doses of low molecular weight heparin (LMWH) on the incidence of bleedings. Methods: The
data of forty-two patients admitted to the Intensive Care Unit (ICU) were retrospectively analyzed. On ICU admission, patients with D-dimer 35) subcutaneously b.i.d. and patients with D-dimer ≥ 3000 ng/mL (Group 2) received enoxaparin 100 UI/kg every 12 h.
Aspirin was administered to all patients once a day. Results: Both groups presented a high incidence of perivascular thrombosis (40.9% in Group 1 and 30% in Group 2). Patients of Group 2 suffered a higher incidence of venous thromboembolism (VTE) than Group
1 (65% vs 13.6%, p = 0.001). One patient (4.5%) of Group 1 and three patients (15%) of Group 2 suffered from minor bleeding; no patient had major bleeding. Group 2 had a longer ICU and hospital stay than Group 1 (11.5 ± 5.6 vs 9.0 ± 4.8 and 30 ± 4.9 vs 21
± 2.3, p < 0.05, respectively) as well as increased ICU mortality (25% vs 9.1%). Conclusions: More severe critically ill COVID-19 patients have a high incidence of VTE and worse outcome, despite the use of heparin at the therapeutic dose. However, the use
of heparin did not increase the incidence of bleeding complications. © 2020 Elsevier Ltd |
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Pérez Dueñas, V, Allona Krauel, et al |
Archivos de Bronconeumologia |
Clinical data| Données cliniques |
This study aimed to evaluate the diagnostic capacity of pulmonary angiography with multidetector computed tomography
(MDCT) and iodine mapping in the diagnosis of pulmonary thromboembolism (PTE) in patients with Covid-19 disease. Of the 81 patients studied 64 (79.01%) men], acute PTE was identified in 22 (27.16%), bilaterally in 13 (59.09%), and 13 (59,09%) showed areas
of hypoperfusion. Of the 59 (72.83%) patients without PTE, hypoperfusion was observed in 41 (69.49%) (attributable in one case to pulmonary emphysema). In 18 (22.2%) of the total number of patients, neither PTE nor hypoperfusion were seen. A crazy paving pattern
is a risk factor for developing PTE (OR 1.94; 95% CI 0.28-13.57), as are consolidations (OR 1.44; 95% CI 0.24-8.48) and septal thickening/bronchiectasis (OR 1.47; 95% CI 0.12-17.81). Patients with O2-refractory SRF showed a 6.36-fold higher risk for hypoperfusion
on the iodine map. |
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Preliminary assessment of air during covid-19 lockdown: An unintended benefit to environment |
Pervaiz, S, Javid, et al |
Environment and Natural Resources Journal |
Public health interventions*| Interventions de santé publique |
The main rationale of the present research is to visualize the air quality during the ‘Lockdown’ period in Lahore,
Pakistan by mapping via online tools and techniques using a geospatial system. According to the present findings, the concentrations of air pollutants, such as particulate matters (PM10 and PM2.5), nitrogen oxides as NO and NO2, and sulphur dioxide, are below
the maximum permissible levels of the Punjab Environmental Quality standards (PEQs), although ozone exceeds its PEQs. So in light of the results, once this COVID-19 crisis is over, the government should speed up measures to lessen air pollution to achieve
targets of sustainable development goals (SDGs). |
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Comparison of clinical data and computed tomography semiotics of the lungs in COVID-19 |
Petrikov, SS, Popugaev, et al |
Tuberculosis and Lung Diseases |
Clinical data| Données cliniques |
The objective of the study: To compare the degree of lung damage according to chest CT data to the clinical state of
COVID-19 patient, to analyze the semiotics and changes in CT data. Subjects and methods. 317 CT scans were retrospectively analyzed; those scans belonged to 98 patients with COVID-19 treated at N.V. Sklifosovsky Research Institute for Emergency Medicine. Patients
were divided into 4 groups, depending on the degree of the lungs damage detected by CT during the primary examination, their clinical state was assessed at each subsequent CT scan. To determine the relationship between the degree of pulmonary changes and the
clinical status of patients, a correlation analysis was performed using the rank correlation method, significance was assessed using the Student's coefficient. Results. It was found that CT allowed to identify changes in the lungs typical of COVID-19 and assess
their degree, as well as to analyze progression or regression lung changes, including comparison with clinical data. A significant correlation was revealed (rs = 0.577) between the growing degree of lung damage, as determined by CT and deterioration of the
clinical status of patients. © 2020 New Terra Publishing House. All rights reserved. |
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Petrov, AI, Petrova, et al |
Sustainability (Switzerland) |
Public Health response| Interventions de santé publique Economics | Économie |
The article presents fundamental approaches to assessing the sustainability of a transport service, particularly city
passenger public transport (CPPT) in the large Russian city Tyumen (size of population-nearly 807 thousand people). Methods of analysis of the sustainability of the transport process in conditions of negative environmental impact (COVID-19 pandemic) are considered.
During the period from 30.03.2020 to 31.05.2020 (nine weeks-the acute phase of COVID-19 pandemic) structural sustainability of the CPPT system in Tyumen remained at a high level. By changing the parameters of the planned characteristics of the CPPT system
state, an attempt to adapt the transport service supply to a sharp decrease in transport demand was made. In the period of "self-isolation", the demand for the CPPT transport service reduced more than the transport service supply. Sustainability of CPPT functioning
was evaluated by calculating the elasticity of the transport supply (number of trips) in relation to the actual demand (actual volume of transportations). Calculation of the elasticity index of the CPPT system of Tyumen during nine weeks of April-May 2020
(duration of "self-isolation") is provided. It was found that the foreground target function of city management was the maintenance of a high level of transportation processes to the detriment of the transportations' effectiveness. Such a policy led to contradictory
results-the additional financial expenses at the rate of 135-150 million rubles and quite a high level of contentment of the Tyumen population with the quality of the CPPT work (sociological research established that 80-85% of respondents were satisfied with
the quality of the transport service in April-May 2020). |
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Piercarlo, SP, Daniela, et al |
Journal of Autoimmunity |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
The aim of this multicentre retrospective study of rheumatic patients in the Italian regions of Lombardy and Marche
was to determine whether patients receiving biological or small molecules treatment are more susceptible to the development of COVID-19 than the general population. Forty-seven of the 7.204 patients were diagnosed with COVID-19, seven of whom died; the patients
who had symptoms resembling those of COVID-19 but had negative swabs were considered negative for the disease. The overall infection rate was 0.65, and the crude case fatality risk (CFR) in the patients with COVID-19 was 14.9%. There was no difference in the
mortality rate among the patients receiving the different individual biological drugs or small molecules. |
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Pisano, TJ, Hakkinen, et al |
Journal of Stroke and Cerebrovascular Diseases |
Clinical data| Données cliniques |
We report a case of 33-year-old African American woman with COVID-19 who developed acute malignant middle cerebral
artery infarction due to thromboembolic occlusion of the left terminal internal carotid artery and middle cerebral artery stem. |
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Placik, DA, Taylor, et al |
Radiology Case Reports |
Clinical data| Données cliniques |
We discuss the case of a 49-year-old male who presented to the emergency department with fever, cough, and shortness
of breath. Initial chest X-ray suggested viral pneumonia that was confirmed to be due to COVID-19. In this case report, we explore the possibility that the patient's immunocompromised state may have contributed to the patient's development of mucormycosis
and subsequent development of bronchopleural fistula. |
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Pokrajac, N, Schertzer, et al |
Western Journal of Emergency Medicine |
Infection Prevention and Control/ Prévention et contrôle des infections (IPAC/PCI)
Healthcare Response | Réponse des soins de santé |
The goal of this study was to determine whether a simulation-based, mastery learning intervention with deliberate practice
improves correct use of PPE by physicians during a simulated clinical encounter with a COVID-19 patient. A total of 117 subjects participated, including 56 faculty members and 61 resident physicians. Participants completed a pretest skills assessment using
a 21-item checklist of steps to correctly don and doff PPE. The primary outcome was a change in assessment scores of correct PPE use following our educational intervention. All participants had a mean pretest score of 73.1% (95% confidence interval [CI], 70.9-75.3%).
Faculty member and resident pretest scores were similar (75.1% vs 71.3%, p = 0.082). Mean pretest doffing scores were lower than donning scores across all participants (65.8% vs 82.8%, p<0.001). Participant scores increased 26.9% (95% CI of the difference
24.7-29.1%, p<0.001) following our educational intervention resulting in all participants meeting the MPS of 100%. |
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Prakash, Swayam, Ruchi, et al |
bioRxiv |
Coronavirology| Coronavirologie Immunology | Immunologie |
By use of several immuno-informatics and sequence alignment approaches, authors identified several human B-cell, CD4+
and CD8+ T cell epitopes that are highly conserved in: (i) greater than 81,000 SARS-CoV-2 human strains identified to date in 190 countries on six continents; (ii) six circulating CoVs that caused previous human outbreaks of the Common Cold; (iii) five SL-CoVs
isolated from bats; (iv) five SL-CoV isolated from pangolins; (v) three SL-CoVs isolated from Civet Cats; and (vi) four MERS strains isolated from camels. Furthermore, they identified cross-reactive asymptomatic epitopes that: (i) recalled B cell, CD4+ and
CD8+ T cell responses from both asymptomatic COVID-19 patients and healthy individuals who were never exposed to SARS-CoV-2; and (ii) induced strong B cell and T cell responses in humanized Human Leukocyte Antigen (HLA)-DR/HLA-A*02:01 double transgenic mice.
The findings herein pave the way to develop a pre-emptive multi-epitope pan-Coronavirus vaccine to protect against past, current, and potential future outbreaks. |
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Prieto, M, Ielpo, et al |
Cirugia Espanola |
Healthcare Response | Réponse des soins de santé |
The aim of this study is to analyze how the treatment of acute appendicitis has been affected during the pandemic.
We received 337 responses from 170 centers. During the first month of the pandemic the incidence of acute appendicitis has decreased. Although conservative management has increased, surgical option has been the most used in both simple and complicated appendicitis.
Despite the fact that the laparoscopic approach continues to be the most widely used in our services, the open approach has increased during this pandemic period. |
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Accidental death from a fall from height at workplace turned out to be a COVID-19 death |
Puzović, V, Baković, et al |
Forensic Science International: Reports |
Clinical data| Données cliniques |
Herein we are reporting the case of a Caucasian male who apparently died in a workplace allegedly by a fall from height
and was found to be SARS-CoV-2 positive just prior to the autopsy. The circumstances of his death required a medicolegal investigation. |
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QadirVID-19: A fusion inhibitor against Novel Coronavirus-2019 for specific management
of COVID-19 |
Qadir, MI |
Pakistan Journal of Pharmaceutical Sciences |
Coronavirology| Coronavirologie |
The objective of the present study was to design a fusion inhibitor for specific management of COVID-19. A series of
BLAST was performed to get an optimized and conservative region of the spike protein of the virus which is used in fusion process. Based on the recent data available, residue 1160-1189 of spike protein of Novel coronavirus-2019 (2019-nCoV) was found highly
conserved region with 100% similarity, with maximum score of 99.5 and with an E-value of 5e-24. Thus, this sequence was selected as a drug. This drug is a synthetic peptide composed of 30 amino acids of Heptad Repeat 2 (HR2) region of spike protein of 2019-nCoV
and was named as QadirVID-19 (Qadir, name of the scientist who developed it and VID-19 from COVID-19). |
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Qian, SZ, Hong, et al |
Frontiers in Medicine |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
The aim of this study was to report the clinical characteristics and outcomes of severe and critical patients with
confirmed COVID-19 infection in Wenzhou city. In this single-centered, retrospective cohort study, authors consecutively enrolled 15 severe and 22 critical adult patients with the COVID-19 infection were included. Twenty-six (68.4%) were men. Most patients
had organ dysfunction during hospitalization, including 11 (29.7%) with ARDS, 8 (21.6%) with acute kidney injury, 17 (45.9%) with acute cardiac injury, and 33 (89.2%) with acute liver dysfunction. Eighteen (48.6%) patients were treated with high-flow ventilation,
9 (13.8%) with non-invasive ventilation, 10 (15.4%) with invasive mechanical ventilation, 7 (18.9%) with prone position ventilation, 6 (16.2%) with extracorporeal membrane oxygenation (ECMO), and 3 (8.1%) with renal replacement therapy. Only 1 (2.7%) patient
had died in the 28-day follow up in our study. All patients had bilateral infiltrates on their chest CT scan. Twenty-one (32.3%) patients presented ground glass opacity (GGO) with critical patients more localized in the periphery and the center. The mortality
of critical patients with the COVID-19 infection is low in the study. Cardiac function was enhanced in the early stage and less likely to develop into acute cardiac injury, but most patients suffered with acute liver injury. The CT imaging presentations of
COVID-19 in critical patients were more likely with consolidation and bilateral lung involvement. |
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Racilan, AM, Assis, et al |
Journal of Endometriosis and Pelvic Pain Disorders |
Immunology | Immunologie |
The present study evaluated whether uterine fibroids and normal myometrium express ACE2 and, if so, at which tissue
compartments. We included 13 premenopausal women (age range 33–50 years, median 40 years) with uterine fibroids undergoing elective hysterectomy or myomectomy. In normal myometrium, ACE2 immunoreactivity was localized in smooth muscle fibers, arteriolar walls,
and endothelial cells. In uterine leiomyoma, ACE2 staining was more intense in smooth muscle cells than in the extracellular matrix, and was also present in vascular endothelium. ACE2 mRNA was detected in myometrium as well as in fibroid samples. Conclusion:
Human myometrium and uterine leiomyoma express ACE2 mRNA and have abundant distribution of ACE2 protein in their smooth muscle cells and microvasculature. |
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Raza, SA, Qazi, et al |
Journal of Educational Computing Research |
Modelling/ prediction| Modélisation/prédiction Public Health response| Interventions
de santé publique |
The COVID-19 Pandemic has led to social isolation; however, with the help of technology, education can continue through
this tough time. Therefore, this research attempts to explore the Unified Theory of Acceptance and Use of Technology (UTAUT) through the expansion of the model. Also, make it relevant to investigate the influence of social isolation, and the moderating role
of Corona fear on Behavioral Intention of the Learning Management System and its Use Behavior of Learning Management System among students. The data was analyzed using Partial Least Square (PLS) and Structural Equation Modelling (SEM). The findings show a
positive link of Performance Expectancy (PE), Effort Expectancy (EE), Social Influence (SI), and Social Isolation on Behavioral Intention of LMS and, also between Behavioral Intention of LMS and its Use behavior. Moreover, the results of the moderation analysis
show that Corona fears only moderates the link of Performance Expectancy and Social influence with Behavioral Intention of LMS. The findings imply the need for improving the LMS experience to increase its Behavioral Intention among students. Finally, the author's
recommendation for future researchers is to examine the extended model in other countries and territories to analyze Coronavirus's influence on e-learning acceptance. © The Author(s) 2020. |
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Rihan, FA, Alsakaji, et al |
Advances in Difference Equations |
Modelling/ prediction| Modélisation/prédiction Transmission |
Environmental factors, such as humidity, precipitation, and temperature, have significant impacts on the spread of
the new strain coronavirus COVID-19 to humans. In this paper, we use a stochastic epidemic SIRC model, with cross-immune class and time-delay in transmission terms, for the spread of COVID-19. We analyze the model and prove the existence and uniqueness of
positive global solution. We deduce the basic reproduction number R0s for the stochastic model which is smaller than R of the corresponding deterministic model. Sufficient conditions that guarantee the existence of a unique ergodic stationary distribution,
using the stochastic Lyapunov function, and conditions for the extinction of the disease are obtained. Our findings show that white noise plays an important part in controlling the spread of the disease; When the white noise is relatively large, the infectious
diseases will become extinct; Re-infection and periodic outbreaks can occur due to the existence of feedback time-delay (or memory) in the transmission terms. © 2020, The Author(s). |
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The new ‘normal’: Rapid adoption of telemedicine in orthopaedics during the COVID-19 pandemic |
Rizzi, AM, Polachek, et al |
Injury |
Healthcare Response | Réponse des soins de santé |
The study assessed patient and surgeon satisfaction and efficacy of telemedicine during a rapid adoption due to the
global pandemic. 612 patients and their orthopaedic surgeons were contacted and each were asked to fill out an survey. Surgeons reported high satisfaction with telemedicine encounters (80%, 86% phone and video respectively), and that 78.4% of the time a telemedicine
encounter was successful in replacing an in-person visit. Patients and orthopaedic surgeons documented high levels of satisfaction with telehealth encounters during the novel coronavirus (COVID-19) pandemic. |
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Sabino, CP, Sellera, et al |
Photodiagnosis and Photodynamic Therapy |
Coronavirology| Coronavirologie |
In this letter to the editor, authors evaluated the inactivation kinetics and reported the UV-C lethal doses (LD) for
SARS-CoV-2. Authors verified that within less than a second, UV-C irradiation was able to inactivate more than 99 % of SARS-CoV-2 viral particles. In fact, LD90 and LD99.999 were achieved at 0.016 and 108.714 mJ/cm2 (0.01 and 49.42 s) respectively. In summary,
the findings can help scientific community and health authorities to develop safe and effective protocols to reduce the dissemination of SARS-CoV-2 during this global health crisis. |
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Sadegh Beigee, F, Pourabdollah Toutkaboni, et al |
Pathology Research and Practice |
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection
d'agents pathogènes |
This study was conducted on 31 deceased patients who were hospitalized for COVID-19 in a tertiary hospital in Tehran,
Iran. A total of 52 postmortem tissue biopsy samples were obtained from the lungs and liver of decedents. The median age of deceased patients was 66 years (range, 30–87 years) and 25 decedents (81 %) were male. The average interval from symptom onset to death
was 13 days (range, 6–34 days). On histopathologic examination of the lung specimens, diffuse alveolar damage and thrombotic microangiopathy were the most common findings (80 % and 60 %, respectively). Liver specimens mainly showed macrovesicular steatosis,
portal lymphoplasmacytic inflammation and passive congestion. No definitive viral inclusions were observed in any of the specimens. In addition, 92 % of lung tissue samples tested positive for SARS-CoV-2 by RT-PCR. |
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Sadiq, M |
Journal of Public Affairs |
Public Health response| Interventions de santé publique |
Police employees have to work extra during uncertain situations as they are responsible to maintain law and order.
Currently, this department is facing a similar situation because of COVID-19. Therefore, this study aims at investigating how police employees' perceptions of workload imbalance their family roles and further increase their job stress and dissatisfaction.
The study collected cross-sectional data from 247 constables performing their duties during lockdown because of COVID-19. Hypotheses were examined using structural equation modeling. The findings revealed that police constables' perception of workload cause
work–family conflict, job stress and job dissatisfaction. In addition, work–family conflict mediates the associations of workload with job stress and job dissatisfaction. The study collected data from a single source, though Harman's single factor confirmed
the absence of common method variance. This study extends the conservation of resource theory and has implications for the management and policymakers. © 2020 John Wiley & Sons Ltd |
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Saez, M, Tobias, et al |
Environmental research |
Epidemiology| Épidémiologie |
The authors used a mixed longitudinal ecological design with the study to assess long-term exposure to nitrogen dioxide
(NO2) and, to a lesser extent, to coarse particles (PM10) have been independent predictors of the spatial spread of COVID-19. For every 1 μm/m3 above the mean the risk of a positive test case increased by 2.7% (95% credibility interval, ICr: 0.8%, 4.7%) for
NO2 and 3.0% (95% ICr: -1.4%,7.44%) for PM10. Regions with levels of NO2 exposure in the third and fourth quartile had 28.8% and 35.7% greater risk of a death, respectively, than regions located in the first two quartiles. Authors hypothesize that the spatial
spread of COVID-19 in Catalonia is attributed to the different ease with which some people, the hosts of the virus, have infected others. That facility depends on the heterogeneous distribution at a small area level of variables such as population density,
poor housing and the mobility of its residents, for which exposure to pollutants has been a surrogate. |
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Sahajpal, NS, Mondal, et al |
Journal of Molecular Diagnostics |
Diagnostics / Pathogen detection| Diagnostics / Détection d'agents pathogènes |
This study investigated the feasibility and accuracy of a sample pooling approach for wide-scale population screening
for coronavirus disease 2019. Of the 94 pools/wells, four were positive Ct values: N (22.7 to 28.3), ORF1ab (23.3 to 27.2), and internal control (34.4 to 35.4)]. The 40 samples comprising the four pools were identified and reanalyzed individually; six samples
were positive, with Ct values of N gene, ORF1ab, and internal control comparable to their respective wells. Additional experiments were performed on samples with high Ct values, and overall results showed 91.6% positive and 100% negative agreement compared
with individual testing approach. Thus, 940 samples were tested in 148 reactions compared with 940 reactions in routine screening. The sample pooling strategy may help catch up with testing needs and minimal turnaround times and facilitate enormous savings
on laboratory supplies, extraction, and PCR kits currently in short supply. |
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Santos-García, D, Oreiro, et al |
Movement Disorders |
Public Health response| Interventions de santé publique |
This is a descriptive, observational, cross-sectional study. An anonymous online survey with 95 questions was distributed
among patients. Of a total of 570 questionnaires received, 568 (99.6%) were considered valid for the analysis (mean age, 63.5 ± 12.5 years; 53% females). A total of 553 patients (97.4%) were aware of the COVID-19 pandemic and 68.8% were concerned about it;
95.6% took preventive measures. A total of 484 patients (85.2%) had no contact with cases of COVID-19, and only 15 (2.6%) had confirmed COVID-19. Although up to 72.7% remained active during confinement, 65.7% perceived a worsening of their symptoms. |
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Sarkar, M, Das, et al |
Environment, Development and Sustainability |
Public health interventions*| Interventions de santé publique |
The study is designed to assess the changes in air quality from the pre-lockdown period to the during lockdown period
in Kolkata and Howrah municipal corporation, West Bengal, India. Significant correlations have been found among the pollutants, ANOVA (Two-Way) has shown the significant mean difference of NAQI between the two phases, F(1,611) = 465.723, p < 0.0001; pairwise
comparison for Ballygunge has shown the highest mean difference 108.194 at p < 0.0001 significant level between lockdown and pre-lockdown phase. Significant positive correlation has been found between PM2.5, PM10 (0.99*); PM2.5, NO2 (0.81*); PM10, NO2 (0.81*);
CO, NO2 (0.77*) and some negative correlations have also been found between O3, NO (− 0.15); O3 and NH3 (− 0.36) in the pre-lockdown phase. The reduction amount of mean concentration from the pre-lockdown phase to during lockdown of the main pollutants like
PM2.5, PM10 and NO2 are ~ 58.71%, ~ 57.92% and ~ 55.23%. Near Rabindra Bharati University constant emission of PM2.5, 10 and NO2 have been recorded due to the nearby Cossipore thermal power station. |
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Saso, A, Skirrow, et al |
Vaccines |
Public Health response| Interventions de santé publique Healthcare Response | Réponse
des soins de santé |
We captured the local experiences of members of the Immunising Pregnant Women and Infants Network (IMPRINT) by conducting
an online survey over 2-weeks in April 2020. Of all respondents, 50% or more reported issues with vaccine delivery within their country. Thematic analysis identified three key themes behind immunization disruption: “access” issues, e.g., logistical barriers,
“provider” issues, e.g., staff shortages and user “concern” about attending immunization appointments due to COVID-19 fear. |
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Schäfer, R, Spohn, et al |
Stem Cell Reports |
Coronavirology| Coronavirologie Therapeutics| Thérapeutique |
We found that mesenchymal stem/stromal cells (MSCs) from bone marrow, amniotic fluid, and adipose tissue carry angiotensin-converting
enzyme 2 and transmembrane protease serine subtype 2 at low levels on the cell surface under steady-state and inflammatory conditions. We did not observe SARS-CoV-2 infection or replication in MSCs at steady state under inflammatory conditions, or in direct
contact with SARS-CoV-2-infected Caco-2 cells. |
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Schmulson, M, Gudiño-Zayas, et al |
Journal of clinical gastroenterology |
Healthcare Response | Réponse des soins de santé |
The aim of this study was to determine the impact of COVID-19 on Neurogastroenterology in Latin America. Sixty-one
members mainly from Colombia, Mexico, and Brazil answered the survey. All reported a negative impact on their practice (88.6%: a 61% to 100% decrease), mainly in office consultations and elective endoscopies. Guidelines to resume activities and policies for
Telemedicine practice and reimbursement are warranted. |
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Development and usability testing of a web-based COVID-19 self-triage platform |
Schrager, JD, Schuler, et al |
Western Journal of Emergency Medicine |
Healthcare Response | Réponse des soins de santé |
We describe the iterative development and usability testing of a web-based, self-triage tool for severe respiratory
syndrome coronavirus 2 (COVID-19 disease) aimed at preventing surges in healthcare utilization. We found that 79.4% of the participants accurately recalled the recommendations provided by the website. Almost all participants (96.9%) found the website easy
to use and navigate. |
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Scuri, P, Iacovoni, et al |
Pulmonary Circulation |
Clinical data| Données cliniques |
Since the beginning of the SARS-CoV-2 outbreak, few cases of COVID-19 pneumonia in patients with pulmonary arterial
hypertension have been reported. We present four patients with known history of PAH admitted to our hospital with SARS-CoV-2 pneumonia to analyze the impact of this disease on their clinical outcome. © The Author(s) 2020. |
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Seery, N, Li, et al |
Multiple Sclerosis and Related Disorders |
Public Health response| Interventions de santé publique |
We aimed to evaluate patient perspectives regarding the use of Natalizumab and anti-CD20 therapies (Rituximab and Ocrelizumab)
in the context of the COVID-19 pandemic. A cross-sectional study conducted via voluntary survey filled in by 170 patients with MS and related disorders receiving their infusional treatment in one MS centre in Australia. Whilst a large proportion of patients
had some concern regarding the impact of their DMT on COVID-19, whether on their risk of contracting COVID-19 or a theoretical risk for more severe disease, the overall level of concern in most cases was at most mild. |
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Weighting bias and inflation in the time of COVID-19: evidence from Swiss transaction data |
Seiler, P |
Swiss Journal of Economics and Statistics |
Economics | Économie |
Using public data from debit card transactions, I quantify these changes in consumer spending, update CPI basket weights
and construct an alternative price index to measure the effect of the COVID-induced weighting bias on the Swiss consumer price index. I find that inflation was higher during the lock-down than suggested by CPI inflation. |
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Selamet, J |
International Journal of Designed Objects |
Public Health response| Interventions de santé publique |
The present study seeks to develop a physical activity initiative for them during this global pandemic. Using the human-centered
design (HCD) approach with the online involvement of twenty-two WFH workers, the results of this study presented the assessment and insights from the sequential HCD process regarding WFH workers’ workstation in the home environment, views on received and tracked
daily physical activities during the outbreak, and feedback from a five-day live physical activity prototyping. |
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Building a tool model for the study of the ecosystem "coronavirus - Vector - human - Environment" |
Sereda, TG, Kostarev, et al |
|
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie Public health
interventions*| Interventions de santé publique |
Two models of solving the problem with COVID19, adopted in different countries, are considered: the first is complete
self-isolation; the second is partial isolation of people with compromised immune systems. A graphic chart of the state and transition model of the Virus Source, Viral Vector, Recipient and Environment (CoV-E-V-P) system was constructed and analyzed. The change
in human health state under the influence of the element parameters of the system is researched. |
|
Shaban, RZ, Nahidi, et al |
American Journal of Infection Control |
Public Health response| Interventions de santé publique |
In this study, we explore the lived experience and perceptions of patients in isolation with COVID-19 in an Australian
healthcare setting. Findings from this study provide a valuable insight into the lived experiences of patients with COVID-19, which reflect those of patients with other infectious diseases who require isolation. |
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Shahani, L, Glazier, et al |
Psychiatry research |
Clinical data| Données cliniques |
At the time of this report (4/17/2020 - 7/17/2020), 45 patients were identified as PUI and appropriately isolated with
droplet precautions. Of the 30 patients offered testing (testing supplies not available initially) all patients consented, and 16 (53%) tested positive and were diagnosed with COVID-19. Fever was the most common symptom present in all patients who were diagnosed
with COVID-19 in our hospital. |
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Shalayel, MH, Al-Mazaideh, et al |
Pakistan Journal of Pharmaceutical Sciences |
Coronavirology| Coronavirologie Therapeutics| Thérapeutique |
Here, we investigated Vitamin D for its in silico potential inhibition of the binding sites of SARS-CoV-2 endoribonuclease
Nsp15. In this study, we selected Remdesivir, Chloroquine, Hydroxychloroquine and Vitamin D to study the potential binding affinity with the putative binding sites of endoribonuclease Nsp15 of COVID-19. Among the results, Vitamin D was found to have the highest
potency with strongest interaction in terms of LBE, lowest RMSD, and lowest inhibition intensity Ki than the other standard compounds. |
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How is COVID-19 reshaping activity-travel behavior? Evidence from a comprehensive survey in Chicago |
Shamshiripour, A, Rahimi, et al |
Transportation Research Interdisciplinary Perspectives |
Public Health response| Interventions de santé publique |
This research is an effort to investigate how and to what extent people's mobility-styles and habitual travel behaviors
have changed during the COVID-19 pandemic and to explore whether these changes will persist afterward or will bounce back to the pre-pandemic situation. Analysis of the collected data reveals significant changes in various aspects of people's travel behavior.
We also provide several insights for policymakers to be able to proactively plan for more equitable, sustainable, and resilient cities. |
|
Shao, S, Zhou, et al |
Journal of Aerosol Science |
Transmission Clinical data| Données cliniques |
Combining in situ measurements and computational fluid dynamics simulations, we quantify the exhaled particles from
normal respiratory behaviors and their transport under elevator, small classroom, and supermarket settings to evaluate the risk of inhaling potentially virus-containing particles. Our results show that the design of ventilation is critical for reducing the
risk of particle encounters. |
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Digital Health Innovation: Exploring Adoption of COVID-19 Digital Contact Tracing Apps |
Sharma, S, Singh, et al |
IEEE Transactions on Engineering Management |
Public Health response| Interventions de santé publique |
This article explores an individual's intention to adopt COVID-19 digital contact tracing (DCT) apps. The study adopts
a quantitative approach collecting data from 714 respondents using a random sampling technique. Empirical results found that the perceived effectiveness of privacy policy negatively influenced privacy concerns, whereas perceived vulnerability had a positive
influence. Expected personal and community-related outcomes of sharing information positively influenced attitudes toward DCT apps, while privacy concerns had a negative effect. |
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Maintaining a safe uro-oncological surgical service in the face of the COVID-19 pandemic |
Shillito, S, O’Flynn, et al |
Journal of Clinical Urology |
Clinical data| Données cliniques |
We report a 26-patient case series performed following national lockdown. Patients were initially screened for COVID-19
symptoms and later all patients required a negative swab pre-operatively. Personal protective equipment using aerosol precautions was used for all cases. Three out of 26 patients developed post-operative pyrexia, but all tested negative for COVID-19. Our results
indicate that during the peak of the COVID-19 pandemic, with appropriate precautions, a safe surgical service can be continued. |
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Gastrointestinal symptoms revealing COVID-19 in Malian breast cancer patient undergoing chemotherapy |
Sidibe, FM, Bathily, et al |
Bulletin du cancer |
Clinical data| Données cliniques |
we report a case of a bone's metastatic breast cancer in Malian patient treated by chemotherapy in whom SARS-COV-2's
diagnosis was made 9 days after the onset gastrointestinal symptoms. Patient quickly died before any COVID-19's treatment. |
|
Simione, L, Gnagnarella, et al |
Frontiers in Psychology |
Public Health response| Interventions de santé publique Healthcare Response | Réponse
des soins de santé |
In this study, we investigated the perception of risk and the worries about COVID-19 infection in both healthcare workers
and the general population in Italy. we administered an online questionnaire about COVID-19 together with other questionnaires assessing the psychological condition of participants. We found that health workers reported higher risk perception, level of worry,
and knowledge as related to COVID-19 infection compared to the general population. Psychological state, sex, and living area were less related to these factors. |
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32889160; COVID-19 Infection and Arterial Thrombosis: Report of Three Cases |
Singh, B, Aly, et al |
Annals of Vascular Surgery |
Clinical data| Données cliniques |
Herein, we report 3 cases of COVID-19 infection complicated by arterial thrombosis in the form of acute limb ischemia.
Our case series adds to the limited literature regarding arterial thrombosis. |
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Impact of COVID-19 Pandemic on Neurosurgical Practice in a Tertiary Care Center in India |
Singh, R, Sahu, et al |
Journal of Neurosciences in Rural Practice |
Healthcare Response | Réponse des soins de santé |
The aim of the study is to determine the magnitude of repercussions of coronavirus disease 2019 (COVID-19) pandemic
on neurosurgical specialty and formulate a management approach. Effects of COVID-19 pandemic on psychology of neurosurgical team (50 members) and on patient party (88) were also evaluated. Virtual learning and webinars as a substitute to residential neurosurgical
training were analyzed by a questionnaire given to 13 neurosurgeons of our department. The COVID-19 pandemic is causing a significant impact on health care systems worldwide. For conserving resources elective surgical procedures should be limited. This pandemic
has a negative impact on neurosurgical resident training program and psychology of both neurosurgical unit and patients. |
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Sisodia, R, Khandelwal, et al |
Journal of Anaesthesiology Clinical Pharmacology |
Infection Prevention and Control/ Prévention et contrôle des infections (IPAC/PCI) |
The chances of getting infected with aerosol is mostly from direct aerosol exposure through nose, mouth and eyes are
high for anesthesiologists. Authors present a cheap, disposable and effective solution for face /neck covering that can be easily created with readily available materials in operation theatres. |
|
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Song, SL, Hays, et al |
Pathogens |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
Explored the association between statin use and severe COVID-19 outcomes in hospitalized patients, including intensive
care unit (ICU) admission, the need for invasive mechanical ventilation (IMV), and in-hospital death, based on a retrospective patient cohort (n=249). After adjusting for age, sex, race, cardiovascular disease, chronic pulmonary disease, diabetes, and obesity,
statin use was significantly associated with decreased risk for IMV (adjusted Odds Ratio (aOR) = 0.45, 95% (CI): 0.20–0.99). The results support the continued use of statins among COVID-19 patients. |
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Spuch, C, López-García, et al |
Frontiers in Pharmacology |
Clinical data| Données cliniques |
Case report of patients with severe COVID-19 infection treated with lithium carbonate. Lithium carbonate significantly
reduced plasma reactive C-Protein levels, increased lymphocyte numbers and decreased the neutrophil-lymphocyte ratio, improving both inflammatory activity and the immune response among patients. |
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Steens, A, Freiesleben de Blasio, et al |
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin |
Public Health response| Interventions de santé publique |
Survey found low self-reported adherence to requested measures among 1,704 individuals (42%; 95% confidence interval:
37–48) In Norway. Adherence was lower in May–June–July (33–38%) compared with April (66%), and higher among those experiencing COVID-19-compatible symptoms (71%) compared with those without (28%). Findings suggest that consideration is required of strategies
to improve people’s adherence to quarantine and isolation. |
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Storch-de-Gracia, P, Leoz-Gordillo, et al |
Anales de Pediatria |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
Retrospective study including patients under 18 years of age admitted with SARS-CoV-2 infection .Cases with uncomplicated
disease (n=24) presented to the emergency department (ED) with fever and/or respiratory symptoms without significant alterations in laboratory findings. Of the 15 children with complicated presentation, 12 developed shock, frequently presented altered appearance,
extreme tachycardia, abdominal pain, vomiting, diarrhea, rash, and/or conjunctival hyperemia. These patients also showed greater lymphopenia, elevated neutrophil/lymphocyte ratio, C-reactive protein, procalcitonin, D-dimer, and ferritin. |
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Stuart, K, Faghy, et al |
International Journal of Sociology and Social Policy |
Public Health response| Interventions de santé publique |
Biopsychosocial (BPS) analysis of COVID-19 experiences was conducted using online narrative research. The findings
illustrate people with a narrow range of BPS characteristics experienced over a wide range of BPS impacts which are nuanced, complex and dynamic. If unaddressed these may create future adverse BPS characteristics. |
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Efficient calibration for imperfect epidemic models with applications to the analysis of COVID-19 |
Sung, Chih-Li, Hung, et al |
arXiv |
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie |
Minimizing the sum of squared distance between actual observations and simulation outputs is often applied to estimate
epidemiological parameters. The authors shown this method is inefficient, and a new estimator is introduced and applied to the analysis of the COVID-19 pandemic for 20 countries based on the SEIR (Susceptible-Exposed-Infectious-Recovered) model with both
deterministic and stochastic simulations. |
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Smart healthcare support for remote patient monitoring during covid-19 quarantine |
Taiwo, O, Ezugwu, et al |
Informatics in Medicine Unlocked |
Healthcare Response | Réponse des soins de santé |
A remote smart home healthcare support system (ShHeS) is proposed for monitoring patients' health status and receiving
doctors’ prescriptions while staying at home. |
|
Tan-Torres Edejer, T, Hanssen, et al |
The Lancet Global Health |
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie Healthcare
Response | Réponse des soins de santé Economics | Économie |
Aimed to identify additional health-care costs of a strategic preparedness and response plan (SPRP) would be if current
transmission levels are maintained in a status quo scenario, or scenarios where transmission is increased or decreased by 50%. The total cost estimate for the COVID-19 response in the status quo scenario was US$52·45 billion over 4 weeks, at $8·60 per capita.
For the decreased or increased transmission scenarios, the totals were $33·08 billion and $61·92 billion, respectively. Costs would triple under the status quo and increased transmission scenarios at 12 weeks. The decreased transmission scenario costs over
12 weeks was equivalent to the cost of the status quo scenario at 4 weeks. By percentage of the overall cost, case management (54%), maintaining essential services (21%), rapid response and case investigation (14%), and infection prevention and control (9%). |
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Unveiling COVID-19 from chest x-ray with deep learning: A hurdles race with small data |
Tartaglione, E, Barbano, et al |
International Journal of Environmental Research and Public Health |
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection
d'agents pathogènes |
Provide clinical findings and methodological guidance on applying deep learning to COVID classification of simple chest
X-ray (CXR) imaging. |
|
Teleworking in Portuguese communities during the COVID-19 pandemic |
Tavares, F, Santos, et al |
Journal of Enterprising Communities |
Public Health response| Interventions de santé publique |
Characterize teleworking carried out in Portuguese communities in the context of the state of emergency caused by the
COVID-19 pandemic. The results show that adapting to teleworking was easy or very easy and that it happened very quickly. The main difficulties encountered by the individuals were the lack of professional interaction/communication with coworkers, the lack
of resources related to support infrastructures, such as the internet or a printer, and the reconciliation of teleworking with family life/household chores/dedication to children and time/schedule management. |
|
Tee, CA, Salido, et al |
Open Access Rheumatology: Research and Reviews |
Healthcare Response | Réponse des soins de santé |
Present the psychological responses of Filipino patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis
(RA) to the COVID-19 pandemic impacts. In the third month of the pandemic in the Philippines, 20% of the respondents with lupus and RA experienced moderate to severe psychological impact. There was moderate to severe anxiety in 38.7% and moderate to severe
depression in 27%. Identification of factors that affect mental health in lupus and RA is useful in implementation of effective psychological support strategies. |
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Policy determinants of COVID-19 pandemic–induced fatality rates across nations |
Teixeira da Silva, JA, Tsigaris, et al |
Public health |
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie Public health
interventions*| Interventions de santé publique Public Health response| Interventions de santé publique |
Model factors influencing COVID-19 mortality across 121 countries by income group. Nations with a higher proportion
of people aged 65+ years had a higher fatality rate. Delaying policies for international travel restrictions, public information campaigns, and testing policies increased the fatality rate. Nations with more cumulative tests per million people showed lower
mortality rates. In contrast, nations where citizens can access more international destinations without a prior visa had higher mortality rates. |
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Immunological features of coronavirus disease 2019 in patients with cancer |
Thibaudin, M, Fumet, et al |
European journal of cancer |
Clinical data| Données cliniques Immunology | Immunologie |
Present immunological features of cancer patients hospitalised for COVID-19 or other concomitant, cancer-related illness.
SARS-CoV-2 infection was associated with CD4 T-cell lymphopenia and inflammatory T-cell response, modification of monocyte activation status, and higher neutrophils and mMDSC and lower CD3 T cells among severe infection patients. |
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Modeling the effects of contact tracing on COVID-19 transmission |
Traoré, A, Konané, et al |
Advances in Difference Equations |
Modelling/ prediction| Modélisation/prédiction Epidemiology| Épidémiologie Public health
interventions*| Interventions de santé publique |
A mathematical model for COVID-19 that involves contact tracing is studied. The contact tracing-induced reproduction
number Rq is compared with the basic reproduction number R0 for the model in the absence of any intervention to assess the possible benefits of the contact tracing strategy. The analysis of the model illustrates contact tracing can reduce the basic reproduction
number R0 (without contact tracing strategy) to values below unity as intended for disease control, thus one would succeed in controlling the epidemic. |
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Characteristics of a Diverse Cohort of Stroke Patients with SARS-CoV-2 and Outcome
by Sex |
Trifan, G, Goldenberg, et al |
Journal of Stroke and Cerebrovascular Diseases |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
Describe the characteristics of a diverse cohort of acute stroke patients with COVID-19 (n=83) and determine the role
of sex on outcome. The most common complications were respiratory failure (59%) and septic shock (34%). Compared with females, a higher proportion of males experienced severe SARS-CoV-2 symptoms requiring ICU hospitalization (73% vs. 49%; p = 0.04). Compared
with females, males had higher mortality (38% vs. 13%; p = 0.02) and were less likely to be discharged home (12% vs. 33%; p = 0.04). After adjustment for age, race/ethnicity, and number of vascular risk factors and morbidity scores were higher in males than
in females (OR = 1.47, 95% CI = 1.03–2.09). |
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Turakhia, Yatish, Thornlow, et al |
bioRxiv |
Epidemiology| Épidémiologie Coronavirology| Coronavirologie |
“genomic contact tracing” – that is, using viral genome sequences to trace local transmission dynamics in real-time
may not be sustainable. Authors propose building an efficient, tree-based data structure encoding the inferred evolutionary history of the virus. Thus approach is reported to improve the speed of phylogenetic placement of new samples and data visualization
by orders of magnitude, thus making it possible to complete the placements under real-time constraints. |
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Utama, ID, Diryana Sudirman, et al |
Journal of Theoretical and Applied Information Technology |
Modelling/ prediction| Modélisation/prédiction Public Health response| Interventions
de santé publique |
This study aims to identify the released factors for patients infected by SARS CoV 2 virus. By taking samples from
South Korea Country, then we were using the data mining process for classifying problems by optimizing the decision tree model from RapidMiner Studio educational 9.6.00 edition. Based on our study showed that the accuracy of this model is 80.46% +/- 1.68%
(micro average 80.46%). The result for this study showed that location or region is a dominant factor rather than age and sex, therefore the South Korea policy to take the drive-through, walk-through, tracing, and use digital maps to let society aware is effective
to prevent the spreads of diseases. The Implication of this study reconfirms that stay away from an infected area or social distancing such as staying at home is the right decision to minimize and reduce pandemic spreads, and other countries can adopt or modify
the strategy that already did in South Korea. © 2005 - ongoing JATIT & LLS. |
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COVID-19: Survey on awareness level and psychological status during the outbreak |
Vaishnavi, P, Ramkumar, et al |
International Journal of Current Research and Review |
Public Health response| Interventions de santé publique |
Survey aimed to discover awareness level, behaviour, attitudes and also to analyze the psychological status related
to coronavirus outbreak in Tamilnadu, India. |
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32622483; Role of extended hemodialysis in COVID-19: a case report |
Valga, F, Vega-Diaz, et al |
Nefrologia |
Clinical data| Données cliniques |
Present the case of a 68-year-old man with a history of hypertension type 2 diabetes mellitus, congestive heart failure,
sleep apnea-hypopnea syndrome, ischemic heart disease and chronic kidney disease stage. |
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Intolerance of uncertainty over covid-19 pandemic and its effect on anxiety and depressive symptoms |
Valle, MV, Andrés, et al |
Interamerican Journal of Psychology |
Public Health response| Interventions de santé publique |
Determine the effect of intolerance of uncertainty over COVID-19 pandemic on anxiety and depressive symptoms during
the quarantine. Regression analyses indicated a significant effect of intolerance of uncertainty on anxiety and on depressive symptoms. A minor effect of age and gender was also found. Young women with greater intolerance of uncertainty showed the highest
levels of anxiety and depressive symptoms. |
|
Vastrad, B, Vastrad, et al |
3 Biotech |
Coronavirology| Coronavirologie |
Identify the differentially expressed genes (DEGs) between SARS-CoV-2 infected and normal control samples to investigate
the molecular mechanisms of infection with SARS-CoV-2. Hub and target genes such as TP53, HRAS, MAPK11, RELA, IKZF3, IFNAR2, SKI, TNFRSF13C, JAK1, TRAF6, KLRF2, CD1A were identified from PPI network, target gene–miRNA regulatory network, and target gene–TF
regulatory network. Additional analysis showed that ten genes (CCL5, IFNAR2, JAK2, MX1, STAT1, BID, CD55, CD80, HAL-B, and HLA-DMA) were substantially involved in SARS-CoV-2 patients. |
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Vogel, AC, Schmidt, et al |
Multiple Sclerosis and Related Disorders |
Healthcare Response | Réponse des soins de santé |
People with MS (n=1019) were surveyed online during the COVID-19 pandemic. A majority of people with MS reported interruptions
to their MS care along the MS care pathway alongside limited access to COVID-19 testing. |
|
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Thrombo-inflammatory features predicting mortality in patients with COVID-19: The FAD-85 score |
Wang, J, Zhang, et al |
Journal of International Medical Research |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
This study explores predictors of critical illness and mortality among adult patients diagnosed with COVID-19 in Wuhan.
Elevated ferritin, tumor necrosis factor-α and D-dimer and decreased albumin concentration were associated with disease severity. Older age, elevated ferritin and elevated interleukin-6 were associated with 28-day mortality. The FAD-85 score, defined as age
+ 0.01 * ferritin +D-dimer, was used to predict risk of mortality. The sensitivity, specificity and accuracy of FAD-85 were 86.4%, 81.8% and 86.4%, respectively. |
|
Warrington, JS, Brett, et al |
Academic Pathology |
Healthcare Response | Réponse des soins de santé |
To improve patient access during the coronavirus disease-19 pandemic, we deployed a mobile unit to enable access to
urine drug testing where needed for patients suffering from substance use disorder. The mobile unit was cost-effective, demonstrating a volume-dependent 19% lower cost compared to pre-coronavirus disease-19 patient service centers in a similar geographic region.
No statistically significant differences were found in substance use positivity rates in comparison to pre-coronavirus disease findings; however, some shifts in use included higher rates of fentanyl and opioid positivity and reductions in tetrahydrocannabinol
and cocaine use in the mobile collections setting. |
|
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Viral filtration efficiency of fabric masks compared with surgical and n95 masks |
Whiley, H, Keerthirathne, et al |
Pathogens |
Infection Prevention and Control/ Prévention et contrôle des infections (IPAC/PCI)
Healthcare Response | Réponse des soins de santé |
This study used a standard mask testing method (ASTM F2101-14) and a model virus (bacteriophage MS2) to test the viral
filtration efficiency (VFE) of fabric masks compared with commercially available disposable, surgical, and N95 masks. The best performing fabric masks were the cotton mask with a section of vacuum cleaner bag or a dried baby wipe in the pocket designed for
a disposable filter, the mask made using the Victorian Department of Health and Human Services guidelines (Australia) and one made from a layer of 100% hemp, a layer of poly membrane, and a layer of cheesecloth. This research supports the use of fabric masks
in the community to prevent the spread of SARS-CoV-2; however, future research is needed to explore the optimum design in ensuring proper fit. |
|
Wu, F, Zhang, et al |
Sustainability (Switzerland) |
Economics | Économie |
To preliminarily determine whether room rate fluctuations and the COVID-19 pandemic were affiliated, analysis was performed
using the average daily room rate and the “coronavirus” Baidu index for Hong Kong. The corresponding Pearson’s correlation coefficient was −0.238 (p < 0.01), indicating a significantly negative correlation between these two factors; that is, when the “coronavirus”
search index was higher, the average hotel room rate on that day was relatively lower. The COVID-19 pandemic, thus, appeared to have a more or less significant negative influence on Hong Kong hotel prices. |
|
|
Xie, C, Ng, et al |
European Journal of Radiology Open |
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection
d'agents pathogènes |
We aimed to develop and validate a CT-based radiomics model to differentiate COVID-19 from other causes of pulmonary
GGOs. This model achieved an AUC of 0.905, accuracy of 89.5 %, sensitivity of 83.3 %, specificity of 90.0 % in the testing set. |
|
|
Xu, Hang, Zhang, et al |
bioRxiv |
Therapeutics| Thérapeutique Animal model | Modèle animal |
Hydroxychloroquine (HCQ), which has been proposed as a therapeutic or prophylactic drug for SARS-COV-2, has been administered
to thousands of individuals with varying efficacy; however, our understanding of its adverse effects is insufficient. In this study, we treated healthy mice with two different doses of (HCQ) that are comparable to clinically administered doses for 7 days.
We found that HCQ increased anxiety behavior at both 24 h and 10 days and enhanced depressive behavior at 24 h. Most of these behavioral and molecular changes were sustained beyond 10 days after drug administration, and some of them were dose-dependent. Although
this animal study does not prove that HCQ has a similar effect in humans, it indicates that HCQ poses a significant risk to mental health and suggests that further clinical investigation is essential. We suggest that individuals who are susceptible to psychiatric
disorders should not take HCQ, especially as a prophylactic drug for SARS-COV-2. |
|
|
Xu, W, Wang, et al |
Frontiers in Immunology |
Epidemiology| Épidémiologie Coronavirology| Coronavirologie |
In the present study, we compared the glycosylation of the S proteins of SARS-CoV-2 and SARS-CoV. Furthermore, we identified
the variations in glycosylation and cell epitopes of SARS-CoV-2 during the global transmission course, and further explored the significance of these changes. The temporal and geographical distributions of the sequences containing amino acid variations were
comprehensively analyzed and a detailed report regarding these distributions was summarized. A total of 228 sequences of variants had multiple variations, of note, most of them harboring the D614G mutation. |
|
|
Yağcı, I, Sarıkaya, et al |
Turkish Journal of Physical Medicine and Rehabilitation |
Healthcare Response | Réponse des soins de santé Economics | Économie |
In this study, we aimed to evaluate the effects of COVID-19 on the physical medicine and rehabiliation (PMR) services
and physiatrists immediately after the first month of pandemic in Turkey. The mean number of inpatients and patients visited that the outpatient clinics significantly decreased after the first reported COVID-19 case. Most of the residents (69%) reported
that their training was seriously affected due to pandemic. From the economic aspect, 69.2% of the participants who were working at private hospitals reported a decrease in their monthly salary, and 21% of them were sent to an unpaid vacation. A total of 21.9%
of private-practice institutions paused their services. |
|
|
COVID-19 pandemic and the incidence of community-acquired pneumonia in elderly people |
Yamamoto, T, Komiya, et al |
Respiratory Investigation |
Healthcare Response | Réponse des soins de santé |
To assess the impact of the COVID-19 pandemic on the incidence of community-acquired pneumonia in elderly people, we
compared the number of elderly patients (≥65 years old) admitted to our hospital with community-acquired pneumonia from January to June 2020 to those from the same period in 2017, 2018, and 2019. The number of elderly patients with community-acquired pneumonia
began to decrease in February 2020, and by April 2020 was significantly lower than in the same period in the three years prior. The measures for COVID-19 infection control may prevent general viral infections, and subsequently, bacterial pneumonia as well. |
|
Chest X-ray findings monitoring COVID-19 disease course and severity |
Yasin, R, Gouda, et al |
Egyptian Journal of Radiology and Nuclear Medicine |
Epidemiology| Épidémiologie Clinical data| Données cliniques |
We aimed to determine the COVID-19 disease course and severity using chest X-ray (CXR) scoring system and correlate
these with patients’ age, sex, and outcome. The total severity score was estimated in the baseline and follow-up CXR and it was ranged from 0 to 8. The outcome of COVID-19 disease was significantly related to the age, sex, and total severity score of the patients. |
|
Ye, Y, Wang, et al |
International Journal of Environmental Research and Public Health |
Public Health response| Interventions de santé publique |
This study focused on the sociological and psychological factors associated with proper and excessive preventive behaviors
of the COVID-19 outbreak in China. The results showed that 54.7% of the participants had adequate basic prevention, 63.6% of the participants had adequate advanced prevention, and 5.8% of the participants practiced excessive prevention. The elder participants
were less likely to engage in proper preventive behaviors. Perceived susceptibility, perceived benefits, perceived barriers, cues to action, and knowledge levels were associated with preventive behaviors. |
|
|
Yu, K, Micco, et al |
American Journal of Otolaryngology - Head and Neck Medicine and Surgery |
Healthcare Response | Réponse des soins de santé |
The objective of this study was to describe current practices and challenges in personal protective equipment (PPE)
use among US otolaryngologists during the COVID-19 pandemic. The majority of participants reported routine access to full PPE for AGPs and pAGPs in all patients, regardless of COVID status. There was a high perception of security, as well as adequate N95 fitting
and PPE training. |
|
|
Clinical efficacy of tocilizumab treatment in severe and critical COVID-19 patients |
Zeng, J, Xie, et al |
World Journal of Clinical Cases |
Clinical data| Données cliniques Therapeutics| Thérapeutique |
The objective of this study was to determine the clinical efficacy of tocilizumab in inhibiting the cytokine storm
in COVID-19. Nineteen severe and critical COVID-19 patients were enrolled in this study, and were treated with tocilizumab in Optical Valley Campus of Hubei Maternal and Child Health Care Hospital from February 20 to March 31, 2020. Thirteen (68.4%) had significantly
improved symptoms of COVID-19. One case was invalid, 1 case was exacerbated, and 4 deaths (21.1%) were observed (all critical cases). Tocilizumab treatment is effective against IL-6 in COVID-19 patients, but it does not completely inhibit the inflammation
and cytokine storm in all patients with COVID-19. |
|
Differential diagnosis of covid-19 pneumonia in cancer patients received radiotherapy |
Zeng, Q, Tang, et al |
International Journal of Medical Sciences |
Clinical data| Données cliniques Diagnostics / Pathogen detection| Diagnostics / Détection
d'agents pathogènes |
This study determined their clinical presentations and radiological features in order to early diagnose and separate
COVID-19 pneumonia from radiation pneumonitis patients promptly. From January 21, 2020 to February 18, 2020, 112 patients diagnosed with suspected COVID-19 were selected consecutively. Despite the comparable morphologic characteristics of lung CT imaging,
the location, extent, and distribution of lung lesions between COVID-19 pneumonia and radiation pneumonitis differed significantly. Lung CT imaging combined with clinical and laboratory findings can facilitate early diagnosis and appropriate management of
COVID-19 pneumonia |
|
Zeshan, M |
Environment, Development and Sustainability |
Economics | Économie |
Using a new Global Trade Analysis Project (GTAP-VA) model, the present study simulates the impact of the double-hit
scenario of Covid-19 on the global value chains and identifies production losses in different sectors of the world economy. Analysis of simulation results indicates that domestic value-added in extraction, light manufacturing and heavy manufacturing export
industries are affected the most globally. Further, the heavy manufacturing sector bears the highest output losses in North America. |
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Impact of the COVID-19 outbreak on the long-range transport of particulate pahs in east
asia |
Zhang, L, Yang, et al |
Aerosol and Air Quality Research |
Public health interventions*| Interventions de santé publique |
Particulate polycyclic aromatic hydrocarbons (PAHs) were continuously observed at a site located in western Japan and
downwind of mainland China that is constantly under the influence of polluted air masses originating from China. The observations showed that the concentration of particulate PAHs sharply dropped to a low level after the implementation of COVID-19 control
measures in China. |
|
Zhao, H, Liu, et al |
Sensors and Actuators, B: Chemical |
Diagnostics / Pathogen detection| Diagnostics / Détection d'agents pathogènes |
Here, we reported an ultrasensitive electrochemical detection technology using calixarene functionalized graphene oxide
for targeting RNA of SARS-CoV-2. Based on a supersandwich-type recognition strategy, the technology was confirmed to practicably detect the RNA of SARS-CoV-2 without nucleic acid amplification and reverse-transcription by using a portable electrochemical smartphone.
The biosensor showed high specificity and selectivity during in silico analysis and actual testing. |
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16th International Conference
on Parallel Problem Solving from Nature, PPSN 2020 |
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Coronavirology| Coronavirologie Therapeutics| Thérapeutique |
The report presents the conference proceedings containing 99 papers. The conference focused on Parallel Problem Solving
from Nature. One of the topics included evolutionary multi-objective design of sars-cov-2 protease inhibitor candidates. |
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International Conference
on Computer Vision and Graphics, ICCVG 2020 |
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Public health interventions*| Interventions de santé publique |
This conference was on Computer Vision and Graphics. The proceedings contain 20 papers. One of the paper was on video-Surveillance
Tools for Monitoring Social Responsibility Under Covid-19 Restrictions. |
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Abdelaziz, TS |
Open Access Macedonian Journal of Medical Sciences |
Review Literature| Revue de littérature |
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The landscape of COVID-19 in cancer patients: Prevalence, impacts, and recommendations |
Abdihamid, O, Cai, et al |
Cancer Management and Research |
Review Literature| Revue de littérature |
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Agarwal, AD |
Open Access Macedonian Journal of Medical Sciences |
Review Literature| Revue de littérature |
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Al-Ani, M, Elemam, et al |
Infection and Drug Resistance |
Review Literature| Revue de littérature |
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Tamoxifen from chemotherapy to antiviral drug: Possible activity against COVID-19 |
Almosawey, H, Al-Khikani, et al |
Biomedical and Biotechnology Research Journal |
Review Literature| Revue de littérature |
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Amaro, R, Mulholland, et al |
Computing in Science and Engineering |
Review Literature| Revue de littérature |
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Enforced remote working and the work-life interface during lockdown |
Anderson, D, Kelliher, et al |
Gender in Management |
Review Literature| Revue de littérature |
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All means all: An introduction to the 2020 Global Education Monitoring Report on inclusion |
Antoninis, M, April, et al |
Prospects |
Review Literature| Revue de littérature |
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Ayseli, YI, Aytekin, et al |
Trends in Food Science and Technology |
Review Literature| Revue de littérature |
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Montelukast Drug May Improve COVID-19 Prognosis: A Review of Evidence |
Barré, J, Sabatier, et al |
Frontiers in Pharmacology |
Review Literature| Revue de littérature |
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The effects of vitamin D on acute viral respiratory infections: A rapid review |
Bradley, R, Schloss, et al |
Advances in Integrative Medicine |
Review Literature| Revue de littérature |
Rapid Review: Medline (OVID), Embase (OVID), AMED (OVID), and CINAHL were searched. Current experimental evidence remains
inconclusive regarding the effects of vitamin D supplementation in the general population for the prevention and treatment of acute respiratory tract infections (ARTI). |
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Brito, PL, Kuffer, et al |
ISPRS International Journal of Geo-Information |
Review Literature| Revue de littérature |
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Impact of SARS-CoV2 infection in pregnant women and its occupational health consequences |
Casta, N, Sentilhes, et al |
Archives des Maladies Professionnelles et de l'Environnement |
Review Literature| Revue de littérature |
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Ceruti, C, Carry, et al |
Praticien en Anesthesie Reanimation |
Review Literature| Revue de littérature |
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Are smoking, environmental pollution, and weather conditions risk factors for covid-19? |
Chatkin, JM, Godoy, et al |
Jornal Brasileiro de Pneumologia |
Review Literature| Revue de littérature |
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32926920; New insights on possible vaccine development against SARS-CoV-2 |
Chaudhry, SN, Hazafa, et al |
Life Sciences |
Review Literature| Revue de littérature |
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Chen, S, Law, et al |
Asia Pacific Journal of Tourism Research |
Review Literature| Revue de littérature |
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Chorney, SR, Rizzi, et al |
American Journal of Otolaryngology - Head and Neck Medicine and Surgery |
Review Literature| Revue de littérature |
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Chua Vi Long, K, Sayed, et al |
Therapeutic Advances in Infectious Disease |
Review Literature| Revue de littérature |
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da Silveira, ES |
International Journal of Latin American Religions |
Review Literature| Revue de littérature |
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Changes in haematological parameters among covid-19 patients |
Dahlawi, H |
International Journal of Current Research and Review |
Review Literature| Revue de littérature |
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32738497; Review of maternal COVID-19 infection: considerations for the pediatric ophthalmologist |
DiSciullo, A, Mokhtari, et al |
Journal of AAPOS |
Review Literature| Revue de littérature |
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32473390; South Indian medicinal plants can combat deadly viruses along with COVID-19? - A
review |
Divya, M, Vijayakumar, et al |
Microbial pathogenesis |
Review Literature| Revue de littérature |
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Convalescent Blood Treatment for COVID-19: Are Local Donors Enough? |
Douglas, PamelaK, Farahani, et al |
arXiv |
Review Literature| Revue de littérature |
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Focosi, D, Maggi, et al |
Reviews in medical virology |
Review Literature| Revue de littérature |
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Fonseka, T, Ellis, et al |
Journal of Clinical Urology |
Review Literature| Revue de littérature |
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Foxton, RM |
Japanese Dental Science Review |
Review Literature| Revue de littérature |
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Practical approach for safe anesthesia in a COVID-19 patient scheduled for emergency laparotomy |
Goneppanavar, U, Desai, et al |
Journal of Anaesthesiology Clinical Pharmacology |
Review Literature| Revue de littérature |
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Neurological Aspects of SARS-CoV-2 Infection: Mechanisms and Manifestations |
Guadarrama-Ortiz, P, Choreño-Parra, et al |
Frontiers in Neurology |
Review Literature| Revue de littérature |
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Gupta, S, Kalra, et al |
Eastern Journal of Medicine |
Review Literature| Revue de littérature |
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Pandemic number five – Latest insights into the COVID-19 crisis |
Häfner, SJ |
Biomedical Journal |
Review Literature| Revue de littérature |
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Hanekamp, YN, Giordano, et al |
Dose-Response |
Review Literature| Revue de littérature |
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Management of the thrombotic risk associated with COVID-19: Guidance for the hemostasis laboratory |
Hardy, M, Lecompte, et al |
Thrombosis Journal |
Review Literature| Revue de littérature |
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Heo, K, Lee, et al |
Annals of global health |
Review Literature| Revue de littérature |
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Selenium and RNA Virus Interactions: Potential Implications for SARS-CoV-2 Infection (COVID-19) |
Hiffler, L, Rakotoambinina, et al |
Frontiers in Nutrition |
Review Literature| Revue de littérature |
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Ibn-Mohammed, T, Mustapha, et al |
Resources, Conservation and Recycling |
Review Literature| Revue de littérature |
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Coronavirus Disease (COVID-19): Current Status and Prospects for Drug and Vaccine Development |
Ita, K |
Archives of Medical Research |
Review Literature| Revue de littérature |
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Jameel, PZ, Taksande, et al |
Sri Lanka Journal of Child Health |
Review Literature| Revue de littérature |
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Kasal, DA, De Lorenzo, et al |
Heart Lung and Circulation |
Review Literature| Revue de littérature |
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Kaur, U, Acharya, et al |
European journal of pharmacology |
Review Literature| Revue de littérature |
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The COVID-19 pandemic in Ireland: An overview of the health service and economic policy response |
Kennelly, B, O'Callaghan, et al |
Health Policy and Technology |
Review Literature| Revue de littérature |
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Kirresh, A, Coghlan, et al |
Cardiovascular Revascularization Medicine |
Review Literature| Revue de littérature |
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Kumar, S, Palta, et al |
Journal of Anaesthesiology Clinical Pharmacology |
Review Literature| Revue de littérature |
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32773409; Coronavirus disease 2019 in children: Clinical & epidemiological implications |
Kuttiatt, VS, Abraham, et al |
Indian Journal of Medical Research, Supplement |
Review Literature| Revue de littérature |
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Kutyrev, VV, Popova, et al |
Problemy Osobo Opasnykh Infektsii |
Review Literature| Revue de littérature |
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Lanza, F, Seghatchian, et al |
Transfusion and Apheresis Science |
Review Literature| Revue de littérature |
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Focus on the depressive symptoms in COVID-19 patients: Perspective based on a rapid meta-analysis |
Lao, Y, Jiang, et al |
Asian Journal of Psychiatry |
Review Literature| Revue de littérature |
MA: searched PubMed, EMBASE, and Cochrane Library from inception to July 30, 2020. Highly elevated prevalence of depressive
symptoms was found in COVID-19 patients not only when treated in hospital but also after hospital discharge, in which a considerable part appeared severe symptoms.
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Lei, ZN, Wu, et al |
Pharmacology and Therapeutics |
Review Literature| Revue de littérature |
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LeSaint, KT, Snyder, et al |
Western Journal of Emergency Medicine |
Review Literature| Revue de littérature |
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Li, X, Xu, et al |
Clinical Epidemiology and Global Health |
Review Literature| Revue de littérature |
SR-MA: WHO database of publications on COVID-19 and PubMed were searched from inception to March 20, 2020. Men older
than 50 with underlying disease are susceptible to develop severe pneumonia while female gender is protective. The typical symptom of severe pneumonia was dyspnea, but high fever, headache and diarrhea were not significantly different among patients with varying
degrees of severity. |
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Litins'ka, Y, Karpenko, et al |
European Journal of Health Law |
Review Literature| Revue de littérature |
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Lu, YF, Pan, et al |
International Journal of Infectious Diseases |
Review Literature| Revue de littérature |
SR-MA: PubMed, EMBASE, and Cochrane Library databases were searched to identify all relevant articles published between
Jan 1, 2020 and June 4, 2020. In conclusion, the incidence of VTE among hospitalised COVID-19 patients was high. Clinical trials are urgently needed to evaluate the roles of prophylactic and therapeutic anticoagulation in COVID-19.
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Gender medicine: Lessons from COVID-19 and other medical conditions for designing health policy |
Machluf, Y, Chaiter, et al |
World Journal of Clinical Cases |
Review Literature| Revue de littérature |
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Maniar, A, Jagannathan, et al |
Journal of Anaesthesiology Clinical Pharmacology |
Review Literature| Revue de littérature |
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McDermott, RJ |
Health Behavior and Policy Review |
Review Literature| Revue de littérature |
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The ventilation of buildings and other mitigating measures for COVID-19: a focus on winter 2020 |
Members, , RAMP, et al |
arXiv |
Review Literature| Revue de littérature |
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Gastrointestinal manifestations of COVID-19 in adults: A review article |
Mohammadi, M, Rajabnia, et al |
Scientific Journal of Kurdistan University of Medical Sciences |
Review Literature| Revue de littérature |
SR: searched PubMed, Embase, Web of Science, and Google Scholar for studies published between 2019, and July 22, 2020.
This review study showed that despite the preliminary opinions, SARS-CoV-2 does not always present with respiratory symptoms.
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Monroig-Bosque, P, Hsu, et al |
Academic Pathology |
Review Literature| Revue de littérature |
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Moodie, N, Ward, et al |
Australian Journal of Social Issues |
Review Literature| Revue de littérature |
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Mental illness in the general population and health professionals during COVID-19: A scoping
review |
Moreira, WC, de Sousa, et al |
Texto e Contexto Enfermagem |
Review Literature| Revue de littérature |
ScR: MEDLINE/PubMed, SCOPUS, Web of Science, PsycINFO, Science Direct databases and in the medRxiv, bioRxiv and PsyArXiv
preprint servers. the Covid-19 pandemic triggered anxiety, depression, stress and post-traumatic stress disorders in the general population and health professionals more often. Women, students and nurses are among the most affected. |
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20 Years of Nordic second-home tourism research: a review and future research agenda |
Müller, DK |
Scandinavian Journal of Hospitality and Tourism |
Review Literature| Revue de littérature |
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Myatra, S, Gupta, et al |
Journal of Anaesthesiology Clinical Pharmacology |
Review Literature| Revue de littérature |
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Vaccines Against Tuberculosis: Problems and Prospects (Review) |
Nadolinskaia, NI, Karpov, et al |
Applied Biochemistry and Microbiology |
Review Literature| Revue de littérature |
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Nemati, H, Ramezani, et al |
Open Access Macedonian Journal of Medical Sciences |
Review Literature| Revue de littérature |
SR: Two databases (PubMed/Medline and Scopus) and bioRxiv were checked for retrieving all types of studies in relation
to ACE2 and COVID-19 until March 18, 2020. In summary, the results showed that the ACE2 receptor for COVID-19 is similar to that of SARS-CoV. However, its expression was different in various populations as well as in the two genders. ACE2 may be used as a
therapeutic target. Patients who take ACE inhibitors may have benefit in severe disease outcomes.
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The first cohort of the COVID-19 patients in Vietnam and the national response to the pandemic |
Nguyen, NH, Van Nguyen, et al |
International Journal of Medical Sciences |
Review Literature| Revue de littérature |
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Diagnostic tests and clinical characteristics of covid-19 in children: An integrative review |
Nunes, MDR, Pacheco, et al |
Texto e Contexto Enfermagem |
Review Literature| Revue de littérature |
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Paital, B, Agrawal, et al |
Environmental Chemistry Letters |
Review Literature| Revue de littérature |
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Coronaviruses as causative agents of severe respiratory diseases |
Panova, AE, Kulikova, et al |
Tuberculosis and Lung Diseases |
Review Literature| Revue de littérature |
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Pemmada, R, Zhu, et al |
Materials |
Review Literature| Revue de littérature |
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Intensive Care Admission and Early Neuro-Rehabilitation. Lessons for COVID-19? |
Pincherle, A, Jöhr, et al |
Frontiers in Neurology |
Review Literature| Revue de littérature |
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Piyush, R, Rajarshi, et al |
Heliyon |
Review Literature| Revue de littérature |
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Pontone, G, Scafuri, et al |
Journal of Cardiovascular Computed Tomography |
Review Literature| Revue de littérature |
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COVID-19 in the Pediatric Population—Review and Current Evidence |
Rabinowicz, S, Leshem, et al |
Current infectious disease reports |
Review Literature| Revue de littérature |
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Iran's Approach to COVID-19: Evolving Treatment Protocols and Ongoing Clinical Trials |
Rahmanzade, R, Rahmanzadeh, et al |
Frontiers in Public Health |
Review Literature| Revue de littérature |
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Rasool, MS, Siddiqui, et al |
Pakistan Journal of Pharmaceutical Sciences |
Review Literature| Revue de littérature |
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Covid-19 and the food chain? Impacts and future research trends |
Rejeb, A, Rejeb, et al |
Logforum |
Review Literature| Revue de littérature |
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Electroencephalographic findings in COVID-19 patients: A systematic review |
Roberto, KT, Espiritu, et al |
Seizure |
Review Literature| Revue de littérature |
SR: systematically searched until July 25, 2020 for published articles that reported on descriptive EEG findings in
patients diagnosed with COVID-19 in PUBMED by Medline, EMBASE, and CENTRAL by the Cochrane Library. The EEG findings in COVID-19 appear to be non-specific. Further research on the relationship of the EEG findings to the clinical state and short- or long-term
prognosis of COVID-19 patients may be conducted to help clinicians discern which patients would necessitate an EEG procedure and would eventually require treatment. |
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Incidence of acute pulmonary embolism in COVID-19 patients: Systematic review and meta-analysis |
Roncon, L, Zuin, et al |
European journal of internal medicine |
Review Literature| Revue de littérature |
SR-MA: searched Medline, Scopus and Web of Science to locate all articles published up to August 1, 2020. The in-hospital
incidence of acute PE among COVID-19 patients is higher in ICU patients compared to those hospitalized in general wards. CTPA was rarely used suggesting a potential underestimation of PE cases.
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32859864; Neurological manifestations of COVID-19: A brief review |
Sachdev, K, Agrawal, et al |
Indian Journal of Medical Research, Supplement |
Review Literature| Revue de littérature |
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Saini, KS, Tagliamento, et al |
European journal of cancer |
Review Literature| Revue de littérature |
SR: search involving peer-reviewed publications, preprints and conference proceedings up to July 16, 2020, was performed.
Patients with cancer who develop COVID-19 have high probability of mortality. Appropriate and aggressive preventive measures must be taken to reduce the risk of COVID-19 in patients with cancer and to optimally manage those who do contract the infection. |
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What is the best treatment option for head and neck cancers in COVID-19 pandemic? A rapid review |
Salari, A, Jalaeefar, et al |
American Journal of Otolaryngology - Head and Neck Medicine and Surgery |
Review Literature| Revue de littérature |
Rapid Review |
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Schoeman, D, Fielding, et al |
Frontiers in Microbiology |
Review Literature| Revue de littérature |
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The mental health impact of the covid-19 pandemic: Implications for sub-saharan africa |
Semo, BW, Frissa, et al |
Psychology Research and Behavior Management |
Review Literature| Revue de littérature |
Rapid Review: search of scientific articles and reports published in English before or on May 17, 2020 was conducted.
Both mental health and psychosocial support need to be integrated into the pandemic response. Treatment efforts should be coupled with a response to support the psychosocial needs of patients and their families.
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Shanmugam, C, Mohammed, et al |
Pathology Research and Practice |
Review Literature| Revue de littérature |
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Sharifi, A, Khavarian-Garmsir, et al |
Science of the Total Environment |
Review Literature| Revue de littérature |
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Shoar, S, Hosseini, et al |
American Journal of Cardiology |
Review Literature| Revue de littérature |
MA: conducted an online search in Medline/PubMed. A significant relationship was observed between mortality and patient
presentation with dyspnea, fatigue, tachycardia, and hypoxemia. Cardiovascular disease-related laboratory biomarkers related to mortality were elevated serum level of lactate dehydrogenase, creatine kinase, brain natriuretic peptide, and cardiac troponin I. |
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The impact of COVID-19 on healthcare worker wellness: A scoping review |
Shreffler, J, Petrey, et al |
Western Journal of Emergency Medicine |
Review Literature| Revue de littérature |
ScR: Between April 6–May 17, 2020, we conducted sys-tematic searches in PubMed, Embase, Cochrane, Clini-cal Key, and
Web of Science. The review of literature revealed consistent reports of stress, anxiety, and depressive symptoms in HCWs as a result of COVID-19.
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Flavonoids: A complementary approach to conventional therapy of COVID-19? |
Solnier, J, Fladerer, et al |
Phytochemistry Reviews |
Review Literature| Revue de littérature |
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Stavridou, A, Stergiopoulou, et al |
Psychiatry and clinical neurosciences |
Review Literature| Revue de littérature |
SR: In conclusion, a deterioration in mental health is highlighted, encompassing anxiety and mood symptoms, and developmental,
stressor‐related, and eating disorders among children, adolescents, and young adults during the COVID‐19 pandemic. |
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COVID-19: Weighing the endeavors of nations, with time to event analysis |
Stephen, S, Issac, et al |
Osong Public Health and Research Perspectives |
Review Literature| Revue de littérature |
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Photoinactivation of coronaviruses: Going along the optical spectrum |
Strakhovskaya, MG, Meerovich, et al |
Laser Physics Letters |
Review Literature| Revue de littérature |
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Swelum, AA, Shafi, et al |
Frontiers in Veterinary Science |
Review Literature| Revue de littérature |
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Tang, CF, Ding, et al |
European journal of pharmacology |
Review Literature| Revue de littérature |
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Systematic review with no meta-analysis of coronavirus COVID-19 |
Tarakji, B, Alali, et al |
Open Access Macedonian Journal of Medical Sciences |
Review Literature| Revue de littérature |
SR: A literature search using MEDLINE, accessed through the National Library of Medicine, PubMed, EMBASE, and
Cochrane systematic review interface, from 2019 to 2020. No clear evidence of the treatment plan and the prevention and most data in literature depending on personal experience only which is different from country to others.
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A Concise Review of Baseline Facts of SARS-CoV-2 for Interdisciplinary Research |
Tyagi, A, Nigam, et al |
ChemistrySelect |
Review Literature| Revue de littérature |
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Ocular manifestations in SARS-CoV-2 positive patients: a systematic review |
Vansjalia, K, Pawa, et al |
Expert Review of Ophthalmology |
Review Literature| Revue de littérature |
SR: searched included Medline, EMBASE, Cumulative Index of Nursing and Allied Health Literature (CINAHL), Clinicaltrials.gov,
ProQuest. Ocular symptoms do not occur commonly among SARS-CoV-2 positive patients; however, this study displays that there is an occurrence of common ocular manifestations such as dry eyes, chemosis, epiphora, and blurred vision.
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Wang, B, Huang, et al |
OncoImmunology |
Review Literature| Revue de littérature |
SR-MA: PubMed, Embase, Web of Science, and the Cochrane Library were systematically searched for relevant articles
published before June 28, 2020. Cancer patients recently under anti-cancer treatment before diagnosed with COVID-19, including surgery, targeted therapy, immunotherapy, and radiotherapy, were not associated with increased risk of exacerbation and mortality.
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Wang, Y, Hu, et al |
Biosensors and Bioelectronics |
Review Literature| Revue de littérature |
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Clinical Challenges in an Outbreak of COVID-19 in Wuhan, China: Concerns from Frontiers |
Wang, Y, Wang, et al |
Current infectious disease reports |
Review Literature| Revue de littérature |
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Online group psychotherapy: Challenges and possibilities during COVID-19-A practice review |
Weinberg, H |
Group Dynamics |
Review Literature| Revue de littérature |
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Neurological Involvement in COVID-19 Patients: A Narrative Review |
Yadav, RD, Srivastava, et al |
Journal of Neurosciences in Rural Practice |
Review Literature| Revue de littérature |
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Yadav, SK, Agrawal, et al |
Indian Journal of Surgery |
Review Literature| Revue de littérature |
ScR: The following databases were searched from January 2020 to 15th June 2020 for relevant studies: Medline, Embase,
Global Health, Scopus, Web of Science Core Collection, WHO, Global Index Medicus, and Google Scholar. This rapid scoping review of rapidly emerging laparoscopic surgery guidelines during COVID-19 found two major research gaps: lack of systematic review of
the evidence (due to the urgency of situation and fear for the safety of HCPs) during their development and insufficient weightage of their impact on surgical services from the global south.
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Research progress of interaction between coronavirus disease 2019 and cardiovascular
system |
Zha, QF, Li, et al |
Journal of Shanghai Jiaotong University (Medical Science) |
Review Literature| Revue de littérature |
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Zhang, W, Lv, et al |
Drug Design, Development and Therapy |
Review Literature| Revue de littérature |
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Abbasi, K |
The BMJ |
Commentary/Editorial| Commentaire/Éditorial |
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Measuring performance during crises and beyond: The Performance Promoter Score |
Aguinis, H, Burgi-Tian, et al |
Business horizons |
Commentary/Editorial| Commentaire/Éditorial |
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Ahmadian, R, Rahimi, et al |
Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas |
Commentary/Editorial| Commentaire/Éditorial |
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32888947; Bilateral Same-Day Cataract Surgery: An Idea Whose Time Has Come #COVID-19 |
Ahmed, IIK, Hill, et al |
Ophthalmology |
Commentary/Editorial| Commentaire/Éditorial |
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Akuhata-Huntington, Z, Foster, et al |
Higher Education Research and Development |
Commentary/Editorial| Commentaire/Éditorial |
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Auditing in times of social distancing: the effect of COVID-19 on auditing quality |
Albitar, K, Gerged, et al |
International Journal of Accounting and Information Management |
Commentary/Editorial| Commentaire/Éditorial |
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Responding to the needs of beedi workers after the outbreak of the COVID-19 pandemic |
Ali, MS, Kumar, et al |
Social Work with Groups |
Commentary/Editorial| Commentaire/Éditorial |
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Editorial: Fifty Campbell systematic reviews relevant to the policy response to COVID-19 |
Aloe, A, Barends, et al |
Campbell Systematic Reviews |
Commentary/Editorial| Commentaire/Éditorial |
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Alquicira-Hernandez, Jose, Powell, et al |
bioRxiv |
Commentary/Editorial| Commentaire/Éditorial |
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Amadasun, S |
International Social Work |
Commentary/Editorial| Commentaire/Éditorial |
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Amadasun, S |
International Social Work |
Commentary/Editorial| Commentaire/Éditorial |
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Ansell, C, Sørensen, et al |
Public Management Review |
Commentary/Editorial| Commentaire/Éditorial |
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Apostol, SA, Lefter, et al |
Studii si Cercetari Fliologice, Seria Limbi Romanice |
Commentary/Editorial| Commentaire/Éditorial |
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32944511; Sharing Solidarity Experiences to Overcome COVID-19 |
Arab-Zozani, M, Hassanipour, et al |
Annals of global health |
Commentary/Editorial| Commentaire/Éditorial |
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Assaad, S, Fuhrmann, et al |
European journal of cancer |
Commentary/Editorial| Commentaire/Éditorial |
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Bades, A |
Journal of Community Nursing |
Commentary/Editorial| Commentaire/Éditorial |
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32773421; Geographical & seasonal variation in COVID-19 related mortality |
Badwe, RA, Dikshit, et al |
Indian Journal of Medical Research, Supplement |
Commentary/Editorial| Commentaire/Éditorial |
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Bagnenko, SF, Rassokhin, et al |
HIV Infection and Immunosuppressive Disorders |
Commentary/Editorial| Commentaire/Éditorial |
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Suicide among children during Covid-19 pandemic: An alarming social issue |
Balachandran, AK, Alagarsamy, et al |
Asian Journal of Psychiatry |
Commentary/Editorial| Commentaire/Éditorial |
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Balakrishnan, JM, Kunju, et al |
Western Journal of Emergency Medicine |
Commentary/Editorial| Commentaire/Éditorial |
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Balavoine, JF |
Revue medicale suisse |
Commentary/Editorial| Commentaire/Éditorial |
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Balluck, J, Asturi, et al |
Nurse Leader |
Commentary/Editorial| Commentaire/Éditorial |
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Barba, V |
Revista de Derecho Civil |
Commentary/Editorial| Commentaire/Éditorial |
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32773418; Observations on healthcare workers & SARS-CoV-2 infection |
Barde, P, Sarkate, et al |
Indian Journal of Medical Research, Supplement |
Commentary/Editorial| Commentaire/Éditorial |
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Barnes, R, Hall, et al |
Journal of Education for Teaching |
Commentary/Editorial| Commentaire/Éditorial |
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Bauchner, H, Malani, et al |
JAMA - Journal of the American Medical Association |
Commentary/Editorial| Commentaire/Éditorial |
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32945253; Travel-associated COVID-19: a challenge for surveillance? |
Beauté, J, Spiteri, et al |
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin |
Commentary/Editorial| Commentaire/Éditorial |
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Beesley, P, Devonald, et al |
Social Work Education |
Commentary/Editorial| Commentaire/Éditorial |
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Rise in cases of alcohol withdrawal following lockdown in dry district of wardha |
Behere, PB, Behere, et al |
Journal of Neurosciences in Rural Practice |
Commentary/Editorial| Commentaire/Éditorial |
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Belančić, A |
Obesity Medicine |
Commentary/Editorial| Commentaire/Éditorial |
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Sustainability and food security after COVID-19: relocalizing food systems? |
Belik, W |
Agricultural and Food Economics |
Commentary/Editorial| Commentaire/Éditorial |
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Beyond COVID-19: Network science and sustainable exit strategies |
Bell, James, Bianconi, et al |
arXiv |
Commentary/Editorial| Commentaire/Éditorial |
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Belyakov, NA, Rassokhin, et al |
HIV Infection and Immunosuppressive Disorders |
Commentary/Editorial| Commentaire/Éditorial |
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Bennani, NN, Bennani-Baiti, et al |
Annals of Oncology |
Commentary/Editorial| Commentaire/Éditorial |
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Managing an oncology clinic during the COVID-19 pandemic—how we did it in Sarajevo? |
Beslija, S |
Memo - Magazine of European Medical Oncology |
Commentary/Editorial| Commentaire/Éditorial |
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Bhaskar, S, Bradley, et al |
Frontiers in Public Health |
Commentary/Editorial| Commentaire/Éditorial |
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Bhavsar, Vishal, Kirkpatrick, et al |
The Lancet Psychiatry |
Commentary/Editorial| Commentaire/Éditorial |
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Bidkar, P, Goneppanavar, et al |
Journal of Anaesthesiology Clinical Pharmacology |
Commentary/Editorial| Commentaire/Éditorial |
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Alcohol consumption and obesity: The hidden scare with COVID-19 severity |
Bilal, B, Saleem, et al |
Medical hypotheses |
Commentary/Editorial| Commentaire/Éditorial |
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The overseer of the plague reading oedipus rex during COVID-19 |
Bilal, MB |
Economic and Political Weekly |
Commentary/Editorial| Commentaire/Éditorial |
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Nurse’s protagonism in structuring and managing a specific unit for covid-19 |
Bitencourt, JVOV, Meschial, et al |
Texto e Contexto Enfermagem |
Commentary/Editorial| Commentaire/Éditorial |
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Boden, LA, Auty, et al |
Frontiers in Veterinary Science |
Commentary/Editorial| Commentaire/Éditorial |
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Bolevich, SB, Litvitsky, et al |
Serbian Journal of Experimental and Clinical Research |
Commentary/Editorial| Commentaire/Éditorial |
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Phosphatidylglycerol and surfactant: A potential treatment for COVID-19? |
Bollag, WB, Gonzales, et al |
Medical hypotheses |
Commentary/Editorial| Commentaire/Éditorial |
|
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Bradby, M |
Journal of Community Nursing |
Commentary/Editorial| Commentaire/Éditorial |
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Brett, M, Goroncy, et al |
Theology |
Commentary/Editorial| Commentaire/Éditorial |
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Britton, E, Richardson, et al |
Alimentary Pharmacology and Therapeutics |
Commentary/Editorial| Commentaire/Éditorial |
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Are Business Valuators Biased? A Psychological Perspective on the Causes of Valuation Disputes |
Broekema, MJR, Strohmaier, et al |
Journal of Behavioral Finance |
Commentary/Editorial| Commentaire/Éditorial |
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32665462; Clarifications on Technologies to Optimize Care of Severe COVID-19 Patients |
Brull, SJ, Kopman, et al |
Anesthesia and Analgesia |
Commentary/Editorial| Commentaire/Éditorial |
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Science standards do address scientific literacy: A reply to Zucker and Noyce |
Brunsell, E, Anderson, et al |
Phi Delta Kappan |
Commentary/Editorial| Commentaire/Éditorial |
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The real body of therapeutic communities in society of lockdown |
Bruschetta, S |
Therapeutic Communities |
Commentary/Editorial| Commentaire/Éditorial |
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The paradoxical effect of IL-6 and implications for the use of Tocilizumab in Covid-19 patients |
Bruzzese, V, Lazzarino, et al |
Medical hypotheses |
Commentary/Editorial| Commentaire/Éditorial |
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Considerations for virtualising
clinical trials in the midst of COVID-19 |
Burgher, S |
Regulatory Rapporteur |
Commentary/Editorial| Commentaire/Éditorial |
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Byrne-Martelli, S |
Journal of pain and symptom management |
Commentary/Editorial| Commentaire/Éditorial |
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Campanozzi, A |
Sri Lanka Journal of Child Health |
Commentary/Editorial| Commentaire/Éditorial |
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The opening salvo of anti-complement therapy against COVID-19 |
Campbell, CourtneyM |
The Lancet Rheumatology |
Commentary/Editorial| Commentaire/Éditorial |
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Campisi, G, Bazzano, et al |
Minerva stomatologica |
Commentary/Editorial| Commentaire/Éditorial |
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Will COVID-19 Containment and Treatment Measures Drive Shifts in Marine Litter Pollution? |
Canning-Clode, J, Sepúlveda, et al |
Frontiers in Marine Science |
Commentary/Editorial| Commentaire/Éditorial |
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Carlson, EB, Gouge, et al |
Journal of Business and Technical Communication |
Commentary/Editorial| Commentaire/Éditorial |
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Carvajal, A, Márquez, et al |
Revista de obstetricia y ginecologia de Venezuela |
Commentary/Editorial| Commentaire/Éditorial |
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COVID-19 as a Harbinger of Transforming Infrastructure Resilience |
Carvalhaes, T, Markolf, et al |
Frontiers in Built Environment |
Commentary/Editorial| Commentaire/Éditorial |
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Carvalho, SFG, Vieira, et al |
Medical hypotheses |
Commentary/Editorial| Commentaire/Éditorial |
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The response of French contract law to the COVID-19 pandemic |
Castro, RP |
Revista de Derecho Civil |
Commentary/Editorial| Commentaire/Éditorial |
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Cepiku, D, Giordano, et al |
Public Money and Management |
Commentary/Editorial| Commentaire/Éditorial |
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Ceresia, F, Misuraca, et al |
Revista de Ciencias Sociales |
Commentary/Editorial| Commentaire/Éditorial |
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Strategic hedging: A "third way" for australian foreign policy in the indo-pacific |
Chan, LH |
Asia Policy |
Commentary/Editorial| Commentaire/Éditorial |
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Chang, JC, Johnson, et al |
American Journal of Infection Control |
Commentary/Editorial| Commentaire/Éditorial |
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32921536; Response to the letter “Does SARS-CoV-2 truly cause infectious myopathy?” |
Chang, KC |
Journal of the Formosan Medical Association |
Commentary/Editorial| Commentaire/Éditorial |
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Chaudhary, M |
Egyptian Journal of Medical Human Genetics |
Commentary/Editorial| Commentaire/Éditorial |
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Chemi, T |
Qualitative Inquiry |
Commentary/Editorial| Commentaire/Éditorial |
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Chen, B, Kessi, et al |
Frontiers in Pediatrics |
Commentary/Editorial| Commentaire/Éditorial |
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Reduction of influenza and enterovirus infection in taiwan during the covid-19 pandemic |
Chen, CHS, Cheng, et al |
Aerosol and Air Quality Research |
Commentary/Editorial| Commentaire/Éditorial |
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Chertoff, JD, Zarzour, et al |
Journal of the American College of Radiology |
Commentary/Editorial| Commentaire/Éditorial |
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32493200; Prevention of COVID-19 infection in the medical population: Possible help from
anosmia? |
Chiarella, G, Pizzolato, et al |
Reviews on Recent Clinical Trials |
Commentary/Editorial| Commentaire/Éditorial |
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Chisholm, M, Kalsi, et al |
HSS Journal |
Commentary/Editorial| Commentaire/Éditorial |
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Choi, JJ, Wehmeyer, et al |
Thrombosis research |
Commentary/Editorial| Commentaire/Éditorial |
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32936118; COVID-19: an opportune period to reform the medical curriculum |
Christopher, E |
The journal of the Royal College of Physicians of Edinburgh |
Commentary/Editorial| Commentaire/Éditorial |
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Citron, F, Perelli, et al |
Prostaglandins Leukotrienes and Essential Fatty Acids |
Commentary/Editorial| Commentaire/Éditorial |
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Cohen, JH |
Migration Letters |
Commentary/Editorial| Commentaire/Éditorial |
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Backtalk: The limits of rapport: What’s lost when we focus on connecting to our students |
Coleman, D |
Phi Delta Kappan |
Commentary/Editorial| Commentaire/Éditorial |
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Contina, A, Yanco, et al |
Ecological Modelling |
Commentary/Editorial| Commentaire/Éditorial |
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Correia, PMAR, Mendes, et al |
Sustainability (Switzerland) |
Commentary/Editorial| Commentaire/Éditorial |
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Scientific production in online journals about the new coronavirus (Covid-19): Bibliometric
research |
Costa, ICP, Sampaio, et al |
Texto e Contexto Enfermagem |
Commentary/Editorial| Commentaire/Éditorial |
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Cottler, LB, Goldberger, et al |
Drug and alcohol dependence |
Commentary/Editorial| Commentaire/Éditorial |
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Coughlin, T |
IEEE Consumer Electronics Magazine |
Commentary/Editorial| Commentaire/Éditorial |
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D’souza, B, Shetty, et al |
International Journal of Healthcare Management |
Commentary/Editorial| Commentaire/Éditorial |
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Safe and Reliable Public Transportation Systems (SALUTARY) in the COVID-19 pandemic |
Darsena, Donatella, Gelli, et al |
arXiv |
Commentary/Editorial| Commentaire/Éditorial |
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Dasgupta, U, Jha, et al |
Economic and Political Weekly |
Commentary/Editorial| Commentaire/Éditorial |
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The impact of the COVID-19 pandemic on social work education and practice in the Netherlands |
de Jonge, E, Kloppenburg, et al |
Social Work Education |
Commentary/Editorial| Commentaire/Éditorial |
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COVID-19: Is it time for pediatric anesthetists to always protect ourselves? |
De Jose Maria, B |
Paediatric anaesthesia |
Commentary/Editorial| Commentaire/Éditorial |
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Protection masks with religious motifs: COVID-19 produces new religious materiality |
de Souza, PR |
International Journal of Latin American Religions |
Commentary/Editorial| Commentaire/Éditorial |
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Insights into neurological dysfunction of critically ill COVID-19 patients |
Deana, C, Verriello, et al |
Trends in Anaesthesia and Critical Care |
Commentary/Editorial| Commentaire/Éditorial |
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Deharo, G, Madanamoothoo, et al |
European Journal of Health Law |
Commentary/Editorial| Commentaire/Éditorial |
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Tackling the COVID-19 pandemic in West Africa: Have we learned from Ebola in Guinea? |
Delamou, A, Sidibé, et al |
Preventive Medicine Reports |
Commentary/Editorial| Commentaire/Éditorial |
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Diomede, F, Marconi, et al |
International Journal of Molecular Sciences |
Commentary/Editorial| Commentaire/Éditorial |
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32941807; Concerns about COVID-19 and arboviral (chikungunya, dengue, zika) concurrent outbreaks |
do Rosário, MS, de Siqueira, et al |
Brazilian Journal of Infectious Diseases |
Commentary/Editorial| Commentaire/Éditorial |
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Dorussen, H |
Peace Economics, Peace Science and Public Policy |
Commentary/Editorial| Commentaire/Éditorial |
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United States congressional COVID-19 legislation: Recent laws and future topics |
Dowling, MK, Terry, et al |
Western Journal of Emergency Medicine |
Commentary/Editorial| Commentaire/Éditorial |
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Durrani, M |
Physics World |
Commentary/Editorial| Commentaire/Éditorial |
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COVID-19 disrupts battery materials and manufacture supply chains, but outlook remains strong |
Dyatkin, B, Meng, et al |
MRS Bulletin |
Commentary/Editorial| Commentaire/Éditorial |
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Economy of Russian regions in the context of the coronavirus epidemic |
Dzobelova, VB, Olisaeva, et al |
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Commentary/Editorial| Commentaire/Éditorial |
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32954705; Lack of MERS-CoV Co-infection among Hospitalized COVID-19 Patients in Saudi Arabia |
Ebrahim, SH |
Journal of epidemiology and global health |
Commentary/Editorial| Commentaire/Éditorial |
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32859863; Will bacille calmette-guerin immunization arrest the covid-19 pandemic? |
Ehtesham, NZ, Samal, et al |
Indian Journal of Medical Research, Supplement |
Commentary/Editorial| Commentaire/Éditorial |
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EkstEen, R |
Tydskrif vir Geesteswetenskappe |
Commentary/Editorial| Commentaire/Éditorial |
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El Maarouf, MD, Belghazi, et al |
Educational Philosophy and Theory |
Commentary/Editorial| Commentaire/Éditorial |
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32954706; The Association between Out-of-Pocket Expenditure and COVID-19 Mortality Globally |
El-Khatib, Z, Otu, et al |
Journal of epidemiology and global health |
Commentary/Editorial| Commentaire/Éditorial |
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Endo, R |
Cultural Studies - Critical Methodologies |
Commentary/Editorial| Commentaire/Éditorial |
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England, E, Jordan, et al |
Clinical imaging |
Commentary/Editorial| Commentaire/Éditorial |
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Esfahani, SA, Lee, et al |
Clinical imaging |
Commentary/Editorial| Commentaire/Éditorial |
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Esparza, J |
Gaceta medica de Caracas |
Commentary/Editorial| Commentaire/Éditorial |
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Evans, RM, Lippman, et al |
Cell Metabolism |
Commentary/Editorial| Commentaire/Éditorial |
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Fagell, PL |
Phi Delta Kappan |
Commentary/Editorial| Commentaire/Éditorial |
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Bariatric Surgery During the COVID-19 Pandemic—the Perspective of Physicians and Patients |
Fakharian, A, Moghadassi, et al |
Obesity Surgery |
Commentary/Editorial| Commentaire/Éditorial |
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Farghaly, TA, Fawzy, et al |
Middle East Fertility Society Journal |
Commentary/Editorial| Commentaire/Éditorial |
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Farmer, RL, McGill, et al |
Professional Psychology: Research and Practice |
Commentary/Editorial| Commentaire/Éditorial |
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Fedotova, GV, Mosolova, et al |
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Commentary/Editorial| Commentaire/Éditorial |
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Ferguson, M |
Phi Delta Kappan |
Commentary/Editorial| Commentaire/Éditorial |
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Figari, F, Fiorio, et al |
Politica Economica |
Commentary/Editorial| Commentaire/Éditorial |
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Finsterer, J, Scorza, et al |
Journal of the Formosan Medical Association |
Commentary/Editorial| Commentaire/Éditorial |
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Fischer, I, Avrashi, et al |
Royal Society Open Science |
Commentary/Editorial| Commentaire/Éditorial |
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Fitzpatrick, E |
Qualitative Inquiry |
Commentary/Editorial| Commentaire/Éditorial |
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Flores, S, Abrukin, et al |
Journal of Emergency Medicine |
Commentary/Editorial| Commentaire/Éditorial |
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Fong, MW, Cowling, et al |
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin |
Commentary/Editorial| Commentaire/Éditorial |
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Foreningen, AI |
Tidsskrift for den Norske laegeforening |
Commentary/Editorial| Commentaire/Éditorial |
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Pension policy in europe and the united states - Towards a new public-private pension mix |
Fornero, E, Wilke, et al |
Politica Economica |
Commentary/Editorial| Commentaire/Éditorial |
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Forsyth, A |
Journal of the American Planning Association |
Commentary/Editorial| Commentaire/Éditorial |
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Franco, A |
Systems |
Commentary/Editorial| Commentaire/Éditorial |
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Nutritional advice for
those with or recovering from Covid-19 |
Franklin, H |
Journal of Community Nursing |
Commentary/Editorial| Commentaire/Éditorial |
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The pathway of COVID-19 pandemic fear: An experience from general practice, Germany |
Freitag, U |
Kathmandu University Medical Journal |
Commentary/Editorial| Commentaire/Éditorial |
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Friedman, SM, Barnett, et al |
American Journal of Lifestyle Medicine |
Commentary/Editorial| Commentaire/Éditorial |
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Introduction to Business and Technical Communication and COVID-19: Communicating in Times of Crisis |
Frith, J |
Journal of Business and Technical Communication |
Commentary/Editorial| Commentaire/Éditorial |
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Fritschi, N, Curtis, et al |
Paediatric Respiratory Reviews |
Commentary/Editorial| Commentaire/Éditorial |
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Gaitonde, M, Ziebell, et al |
Journal of the American Society of Echocardiography |
Commentary/Editorial| Commentaire/Éditorial |
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Diagnostic
screening aid for asymptomatic COVID-19 dental patients |
Gali, S |
Trends in Biomaterials and Artificial Organs |
Commentary/Editorial| Commentaire/Éditorial |
|
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Coronavirus contamination in dental clinics. New systems and operating devices |
Gandolfi, MG, Spinelli, et al |
Dental Cadmos |
Commentary/Editorial| Commentaire/Éditorial |
|
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Government-dictated regulations on contracts in view of COVID-19 in Spain |
García Rubio, MP |
Revista de Derecho Civil |
Commentary/Editorial| Commentaire/Éditorial |
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García-Sánchez, IM, Raimo, et al |
Sustainability (Switzerland) |
Commentary/Editorial| Commentaire/Éditorial |
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XR-Based Mindfulness and Art Therapy: Facing the Psychological Impact of Covid-19 Emergency |
Gatto, C, D’Errico, et al |
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Commentary/Editorial| Commentaire/Éditorial |
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32949701; The 2020 Grand Magal of Touba, Senegal in the time of the COVID-19 pandemic |
Gautret, P, Goumballa, et al |
Travel Medicine and Infectious Disease |
Commentary/Editorial| Commentaire/Éditorial |
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Gavazza, A, Marchegiani, et al |
Frontiers in Public Health |
Commentary/Editorial| Commentaire/Éditorial |
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Georgiev, T, Angelov, et al |
World Journal of Clinical Cases |
Commentary/Editorial| Commentaire/Éditorial |
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Gerall, C, Cheung, et al |
Journal of pediatric surgery |
Commentary/Editorial| Commentaire/Éditorial |
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Gillis, A, Krull, et al |
Teaching Sociology |
Commentary/Editorial| Commentaire/Éditorial |
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Godlee, F |
The BMJ |
Commentary/Editorial| Commentaire/Éditorial |
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Point-of-care ultrasound for intubation confirmation of COVID-19 patients |
Gottlieb, M, Alerhand, et al |
Western Journal of Emergency Medicine |
Commentary/Editorial| Commentaire/Éditorial |
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Gouda, D, Goudra, et al |
Indian Journal of Medical Research, Supplement |
Commentary/Editorial| Commentaire/Éditorial |
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Grace, R, Tham, et al |
Journal of Business and Technical Communication |
Commentary/Editorial| Commentaire/Éditorial |
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Misinformation Inoculation and Literacy Support Tweetorials on COVID-19 |
Graham, SS |
Journal of Business and Technical Communication |
Commentary/Editorial| Commentaire/Éditorial |
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(In)visibility in the margins: COVID-19, women entrepreneurs and the need for inclusive recovery |
Grandy, G, Cukier, et al |
Gender in Management |
Commentary/Editorial| Commentaire/Éditorial |
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Protecting the elderly through and beyond the Covid-19 lockdown |
Gray, V |
Journal of Community Nursing |
Commentary/Editorial| Commentaire/Éditorial |
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Green, JS, Dillane, et al |
Anesthesia and Analgesia |
Commentary/Editorial| Commentaire/Éditorial |
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Community Infrastructuring as Necessary Ingenuity in the COVID-19 Pandemic |
Greenberg, D, Calabrese Barton, et al |
Educational Researcher |
Commentary/Editorial| Commentaire/Éditorial |
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Grinevich, VB, Gubonina, et al |
Cardiovascular Therapy and Prevention (Russian Federation) |
Commentary/Editorial| Commentaire/Éditorial |
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Groeneboom, Piet |
arXiv |
Commentary/Editorial| Commentaire/Éditorial |
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Gromova, OA, Yu, et al |
Farmakoekonomika |
Commentary/Editorial| Commentaire/Éditorial |
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Guido-Estrada, N, Crawford, et al |
Pediatric neurology |
Commentary/Editorial| Commentaire/Éditorial |
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Dagur í lífi sérnámslæknis: Á svæfingu/gjörgæslu í byrjun COVID-19-faraldurs |
Gunnarsdóttir, S |
Laeknabladid |
Commentary/Editorial| Commentaire/Éditorial |
|
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Diabetic ketoacidosis treatment during COVID-19 pandemic in a country with scarce health resources |
Gutiérrez-Ortiz, CC, Concepción-Zavaleta, et al |
Diabetes and Metabolic Syndrome: Clinical Research and Reviews |
Commentary/Editorial| Commentaire/Éditorial |
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Habli, I, Alexander, et al |
BMJ health & care informatics |
Commentary/Editorial| Commentaire/Éditorial |
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Hang, A, Dascalu, et al |
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Commentary/Editorial| Commentaire/Éditorial |
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Hargaden, K |
Theology |
Commentary/Editorial| Commentaire/Éditorial |
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Hartford, EA, Keilman, et al |
Disaster Medicine and Public Health Preparedness |
Commentary/Editorial| Commentaire/Éditorial |
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Heinemann, MK |
The Thoracic and cardiovascular surgeon |
Commentary/Editorial| Commentaire/Éditorial |
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Hess, FU |
Hydrocarbon Processing |
Commentary/Editorial| Commentaire/Éditorial |
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32936703; Nutritional management of patients during and after COVID-19 illness |
Holdoway, A |
British journal of community nursing |
Commentary/Editorial| Commentaire/Éditorial |
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Medical device laws in
Germany, the impact of COVID-19 and brexit |
Holtorf, ML, Traumann, et al |
Regulatory Rapporteur |
Commentary/Editorial| Commentaire/Éditorial |
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Hostmaelingen, N, Bentzen, et al |
BMJ Global Health |
Commentary/Editorial| Commentaire/Éditorial |
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32941560; Utilization of telehealth services during the COVID-19 pandemic |
Hoyer, P, Ahatov, et al |
Cutis |
Commentary/Editorial| Commentaire/Éditorial |
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Hrabí, M |
Biometric Technology Today |
Commentary/Editorial| Commentaire/Éditorial |
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Hu, CF, Zhu, et al |
Journal of Shanghai Jiaotong University (Medical Science) |
Commentary/Editorial| Commentaire/Éditorial |
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32917427; COVID-19: Optimizing healthcare provider wellness and posttraumatic growth |
Huecker, M, Shreffler, et al |
American Journal of Emergency Medicine |
Commentary/Editorial| Commentaire/Éditorial |
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New environmental factors affecting cost systems design after COVID-19 |
Humeedat, MM |
Management Science Letters |
Commentary/Editorial| Commentaire/Éditorial |
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Management of pregnant laboring women during COVID-19 pandemic |
Jain, K, Bhatia, et al |
Journal of Anaesthesiology Clinical Pharmacology |
Commentary/Editorial| Commentaire/Éditorial |
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Does a younger host make the virus weaker? Presenting a new hypothesis |
Jayadevan, R, Raveendran, et al |
Diabetes and Metabolic Syndrome: Clinical Research and Reviews |
Commentary/Editorial| Commentaire/Éditorial |
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Jerjes-Sánchez, C |
Archivos de cardiologia de Mexico |
Commentary/Editorial| Commentaire/Éditorial |
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Jiang, B, Yao, et al |
British journal of anaesthesia |
Commentary/Editorial| Commentaire/Éditorial |
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John, J, Kesner, et al |
African Journal of Urology |
Commentary/Editorial| Commentaire/Éditorial |
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The tooth about nightingale: A reflection on redeployment to nightingale hospital London |
Johnson, EL, Smith, et al |
Dental update |
Commentary/Editorial| Commentaire/Éditorial |
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Johnson, SK |
Studia Liturgica |
Commentary/Editorial| Commentaire/Éditorial |
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32919809; Air leaks, pneumatoceles, and air spaces in Covid-19 pneumonia |
Jolobe, OMP |
American Journal of Emergency Medicine |
Commentary/Editorial| Commentaire/Éditorial |
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Acute stress disorder with panic episodes induced by exposure to COVID-19 outbreak news in a
child |
Kaba, D, Sari, et al |
Dusunen Adam |
Commentary/Editorial| Commentaire/Éditorial |
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Kaharuddin, Djuwairiah Ahmad, M, et al |
Systematic Reviews in Pharmacy |
Commentary/Editorial| Commentaire/Éditorial |
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Kalidoss, VK, Bakshi, et al |
The journal of the Royal College of Physicians of Edinburgh |
Commentary/Editorial| Commentaire/Éditorial |
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Kapitsinis, N |
Regional Science Policy and Practice |
Commentary/Editorial| Commentaire/Éditorial |
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Covid-19: Traditional and complementary healing practices in the pandemic process |
Kaplan, M |
Milli Folklor |
Commentary/Editorial| Commentaire/Éditorial |
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32773410; Hydroxychloroquine prophylaxis for sars-cov-2 infection among healthcare workers |
Karim, HMR, Ahmed, et al |
Indian Journal of Medical Research, Supplement |
Commentary/Editorial| Commentaire/Éditorial |
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Kasapoğlu Akyol, ÜP |
Milli Folklor |
Commentary/Editorial| Commentaire/Éditorial |
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Aerosol anguish in dentistry in COVID-19 pandemic: A hypotheses or reality? |
Kaur, H, Kochhar, et al |
Medical hypotheses |
Commentary/Editorial| Commentaire/Éditorial |
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Kaye, AD, Manchikanti, et al |
Pain physician |
Commentary/Editorial| Commentaire/Éditorial |
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Kelly, K, Soto, et al |
Criminal Justice Review |
Commentary/Editorial| Commentaire/Éditorial |
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Impact of Fear of COVID-19 Pandemic on the Mental Health of Nurses in Pakistan |
Khattak, SR, Saeed, et al |
Journal of Loss and Trauma |
Commentary/Editorial| Commentaire/Éditorial |
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Kim, BH |
Journal of Public Budgeting, Accounting and Financial Management |
Commentary/Editorial| Commentaire/Éditorial |
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Kleen, TO, Galdon, et al |
Frontiers in Immunology |
Commentary/Editorial| Commentaire/Éditorial |
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Is It Fake News or Is It Open Science? Science Communication in the COVID-19 Pandemic |
Koerber, A |
Journal of Business and Technical Communication |
Commentary/Editorial| Commentaire/Éditorial |
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Kohler, JC, Wright, et al |
Journal of Pharmaceutical Policy and Practice |
Commentary/Editorial| Commentaire/Éditorial |
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Krajewski, R, Gołębiowska, et al |
Clinica Chimica Acta |
Commentary/Editorial| Commentaire/Éditorial |
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Digitale middelen in de strijd tegen covid-19: Is een
tweede golf te voorkomen? |
Kretzschmar, MEE, Bruijning-Verhagen, et al |
Nederlands tijdschrift voor geneeskunde |
Commentary/Editorial| Commentaire/Éditorial |
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Kuhlmann, E, Dussault, et al |
European journal of public health |
Commentary/Editorial| Commentaire/Éditorial |
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32773422; Observations on article on healthcare workers & SARS-CoV-2 infection |
Kulkarni, AP |
Indian Journal of Medical Research, Supplement |
Commentary/Editorial| Commentaire/Éditorial |
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Kumar, AP |
Economic and Political Weekly |
Commentary/Editorial| Commentaire/Éditorial |
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Kumar, V |
International immunopharmacology |
Commentary/Editorial| Commentaire/Éditorial |
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Kuo, WH |
East Asian Science, Technology and Society |
Commentary/Editorial| Commentaire/Éditorial |
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The Impact of the 2019 Coronavirus Disease (COVID-19) Pandemic on Sleep Health |
Kutana, S, Lau, et al |
Canadian Psychology |
Commentary/Editorial| Commentaire/Éditorial |
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Lai, R, Chen, et al |
Epidemiology and infection |
Commentary/Editorial| Commentaire/Éditorial |
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Lassandari, A |
Lavoro e Diritto |
Commentary/Editorial| Commentaire/Éditorial |
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Laws, A |
Journal of Community Nursing |
Commentary/Editorial| Commentaire/Éditorial |
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Viewpoint: climate change, health and pandemics – a wake-up call from COVID-19 |
Leal-Filho, W, Nagy, et al |
International Journal of Climate Change Strategies and Management |
Commentary/Editorial| Commentaire/Éditorial |
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Ledesma-Lois, F |
Revista de Derecho Civil |
Commentary/Editorial| Commentaire/Éditorial |
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Lee, JK |
Osong Public Health and Research Perspectives |
Commentary/Editorial| Commentaire/Éditorial |
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The German legislative measures related to the COVID-19 crisis in the area of
civil law |
Lehmann, M |
Revista de Derecho Civil |
Commentary/Editorial| Commentaire/Éditorial |
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The Scientific Foundation of Chinese Herbal Medicine against COVID-19 |
Leung, ELH, Pan, et al |
Engineering |
Commentary/Editorial| Commentaire/Éditorial |
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Lewis, PJ, Morris, et al |
Clinical oncology |
Commentary/Editorial| Commentaire/Éditorial |
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Lim, JX, Leong, et al |
World Neurosurgery |
Commentary/Editorial| Commentaire/Éditorial |
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COVID-19 and the Heart: ACE2 Level and the Company it Keeps Hold the Key |
Lin, HB, Liu, et al |
JACC: Basic to Translational Science |
Commentary/Editorial| Commentaire/Éditorial |
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Public pension reform and the 49th parallel: Lessons from Canada for the U.S |
Lipshitz, C, Walter, et al |
Financial Markets, Institutions and Instruments |
Commentary/Editorial| Commentaire/Éditorial |
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Liu, DCY, Ho, et al |
Dental update |
Commentary/Editorial| Commentaire/Éditorial |
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Can pandemics transform scientific novelty? Evidence from COVID-19 |
Liu, Meijun, Bu, et al |
arXiv |
Commentary/Editorial| Commentaire/Éditorial |
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The “Societalization” of pandemic unpreparedness: lessons from Taiwan’s COVID response |
Lo, MCM, Hsieh, et al |
American Journal of Cultural Sociology |
Commentary/Editorial| Commentaire/Éditorial |
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A year of change for Hong Kong: from east-meets-west to east-clashes-with-west |
Lo, WYW |
Higher Education Research and Development |
Commentary/Editorial| Commentaire/Éditorial |
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López López, L, McCaw, et al |
History of Education Review |
Commentary/Editorial| Commentaire/Éditorial |
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32912670; COVID-19 natural herd immunity and risk of neuropsychiatric disorders |
Losilla-Rodríguez, B, Maldonado, et al |
Revista de Psiquiatria y Salud Mental |
Commentary/Editorial| Commentaire/Éditorial |
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Lotfi, M, Rezaei, et al |
Biomedicine and Pharmacotherapy |
Commentary/Editorial| Commentaire/Éditorial |
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Lucas, GN |
Sri Lanka Journal of Child Health |
Commentary/Editorial| Commentaire/Éditorial |
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Ma, Z |
Advanced Science |
Commentary/Editorial| Commentaire/Éditorial |
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Hidden scars: The impact of violence and the COVID-19 pandemic on children's mental health |
Maalla M'Jid, N |
Child and Adolescent Psychiatry and Mental Health |
Commentary/Editorial| Commentaire/Éditorial |
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MacDonald, P |
Journal of Community Nursing |
Commentary/Editorial| Commentaire/Éditorial |
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Splendid isolation: A practical guide to the use of rubber dam part 1 |
Mackenzie, L, Waplington, et al |
Dental update |
Commentary/Editorial| Commentaire/Éditorial |
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Coronavirus Disease 2019: Quick Diet and Nutrition Guide for Patients With Chronic Kidney Disease |
Mafra, D, Cardozo, et al |
Journal of Renal Nutrition |
Commentary/Editorial| Commentaire/Éditorial |
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Mahajan, V, Ray, et al |
Anesthesia and Analgesia |
Commentary/Editorial| Commentaire/Éditorial |
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Mahendra, L |
International Journal of Current Research and Review |
Commentary/Editorial| Commentaire/Éditorial |
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Mainkar, PS, Ambica, et al |
Current science |
Commentary/Editorial| Commentaire/Éditorial |
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Malagola, M, Polverelli, et al |
Frontiers in Oncology |
Commentary/Editorial| Commentaire/Éditorial |
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The Screening of You and Me: Effects of COVID-19 on Counterproductive Work Behaviors |
Malik, A, Sinha, et al |
IEEE Engineering Management Review |
Commentary/Editorial| Commentaire/Éditorial |
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Mamun, MA, Syed, et al |
Journal of psychiatric research |
Commentary/Editorial| Commentaire/Éditorial |
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32773415; Hydroxychloroquine for chemoprophylaxis in COVID-19: A case of motivated perception? |
Manjunath, BG, Tyagi, et al |
Indian Journal of Medical Research, Supplement |
Commentary/Editorial| Commentaire/Éditorial |
|
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32941563; COVID-19: a dermatologist's experience from the US epicenter |
Mansouri, Y |
Cutis |
Commentary/Editorial| Commentaire/Éditorial |
|
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Mardani, M |
Archives of Clinical Infectious Diseases |
Commentary/Editorial| Commentaire/Éditorial |
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Marginson, S |
Higher Education Research and Development |
Commentary/Editorial| Commentaire/Éditorial |
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Martin-Broto, J, Hindi, et al |
Oncologist |
Commentary/Editorial| Commentaire/Éditorial |
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32705982; Coronavirus disease 2019: Implications for ophtalmology |
Martins, TGDS |
Acta Medica Portuguesa |
Commentary/Editorial| Commentaire/Éditorial |
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McCaw, ZR, Tian, et al |
Contemporary Clinical Trials |
Commentary/Editorial| Commentaire/Éditorial |
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McGrath, BA, Brenner, et al |
British journal of anaesthesia |
Commentary/Editorial| Commentaire/Éditorial |
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Business
trends: Managing risk and uncertainty: The importance of optimizing your value chain |
McMullen, J |
Hydrocarbon Processing |
Commentary/Editorial| Commentaire/Éditorial |
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The COVID-19 pandemic informs future directions of US research universities |
Meiksin, J |
MRS Bulletin |
Commentary/Editorial| Commentaire/Éditorial |
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Mercuri, V, D’Amico, et al |
Journal of endocrinological investigation |
Commentary/Editorial| Commentaire/Éditorial |
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Meyer, NJ, Lindell, et al |
JAMA Internal Medicine |
Commentary/Editorial| Commentaire/Éditorial |
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Mobbs, RJ, Betteridge, et al |
Journal of Spine Surgery |
Commentary/Editorial| Commentaire/Éditorial |
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Mohammad, A, Goli, et al |
Resources, Conservation and Recycling |
Commentary/Editorial| Commentaire/Éditorial |
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Reintroduction of native centric education for children in COVID-19 lockdown |
Monday, OI |
Sri Lanka Journal of Child Health |
Commentary/Editorial| Commentaire/Éditorial |
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Mueller, V, Sheriff, et al |
Applied Economic Perspectives and Policy |
Commentary/Editorial| Commentaire/Éditorial |
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Mustafa, H, Alradhawi, et al |
International Journal of Surgery |
Commentary/Editorial| Commentaire/Éditorial |
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32936122; Impact of COVID-19 on the 'art' of physical examination: a sincere concern |
Naik, BS, M, et al |
The journal of the Royal College of Physicians of Edinburgh |
Commentary/Editorial| Commentaire/Éditorial |
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Potential Application of Drosophila melanogaster as a Model Organism in COVID-19-Related Research |
Nainu, F, Rahmatika, et al |
Frontiers in Pharmacology |
Commentary/Editorial| Commentaire/Éditorial |
|
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Nasrallah, HA |
Current Psychiatry |
Commentary/Editorial| Commentaire/Éditorial |
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Social assistance institutions during the COVID-19 pandemic: Experiences of Polish social workers |
Necel, R, Zaręba, et al |
International Social Work |
Commentary/Editorial| Commentaire/Éditorial |
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Nedunchezhian, AS, Ajayan, et al |
Journal of Neurosciences in Rural Practice |
Commentary/Editorial| Commentaire/Éditorial |
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Treatment recommendations for mechanical ventilation of COVID‑19 patients |
Neetz, B, Herth, et al |
Gefasschirurgie |
Commentary/Editorial| Commentaire/Éditorial |
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Dying alone and lonely dying: Media discourse and pandemic conditions |
Nelson-Becker, H, Victor, et al |
Journal of Aging Studies |
Commentary/Editorial| Commentaire/Éditorial |
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Neves, FS |
Indian Journal of Medical Research, Supplement |
Commentary/Editorial| Commentaire/Éditorial |
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Nichols, CE, Jalali, et al |
Politics and Gender |
Commentary/Editorial| Commentaire/Éditorial |
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Reconsidering the 1918-19 Influenza Pandemic in the Age of COVID-19 |
Nichols, CM, Bristow, et al |
Journal of the Gilded Age and Progressive Era |
Commentary/Editorial| Commentaire/Éditorial |
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Niewiadomski, P |
Logforum |
Commentary/Editorial| Commentaire/Éditorial |
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Niranjan, V, Kinnersley, et al |
Indian Journal of Medical Research, Supplement |
Commentary/Editorial| Commentaire/Éditorial |
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Niranjana, T |
Inter-Asia Cultural Studies |
Commentary/Editorial| Commentaire/Éditorial |
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Confronting the big challenges of our time: making a difference during and after COVID-19 |
O’Flynn, J |
Public Management Review |
Commentary/Editorial| Commentaire/Éditorial |
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Ochoa Yupanqui, WW, Lizana, et al |
Revista Cubana de Investigaciones Biomedicas |
Commentary/Editorial| Commentaire/Éditorial |
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God’s self-distancing: what a global pandemic might teach us about God |
Ochs, C |
Theology |
Commentary/Editorial| Commentaire/Éditorial |
|
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Odinga, MM, Kuria, et al |
Gates Open Research |
Commentary/Editorial| Commentaire/Éditorial |
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Reimagining Botswana’s national security in light of COVID-19 |
Ookeditse, L |
African Security Review |
Commentary/Editorial| Commentaire/Éditorial |
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Oswal, SK, Palmer, et al |
Journal of Business and Technical Communication |
Commentary/Editorial| Commentaire/Éditorial |
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The cultural change of the perception of elderliness during coronavirus outbreak |
Özdemir, M |
Milli Folklor |
Commentary/Editorial| Commentaire/Éditorial |
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32907789; COVID-19 lockdown learning: The revolution of virtual teaching |
Padley, RH, Di Pace, et al |
Journal of Plastic, Reconstructive and Aesthetic Surgery |
Commentary/Editorial| Commentaire/Éditorial |
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Pamučar, D, Žižović, et al |
Sustainability (Switzerland) |
Commentary/Editorial| Commentaire/Éditorial |
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Panayiotou, A |
Gender in Management |
Commentary/Editorial| Commentaire/Éditorial |
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Treatment experience for opioid use disorder during COVID-19 in India: Learning from patients |
Pandit, PM, Bhatia, et al |
Journal of substance abuse treatment |
Commentary/Editorial| Commentaire/Éditorial |
|
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32911560; COVID-19 and sodium-glucose cotransporter 2 inhibitors: No fear to attempt? |
Papachristou, S, Penlioglou, et al |
Experimental and Clinical Endocrinology and Diabetes |
Commentary/Editorial| Commentaire/Éditorial |
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Paredes-Chacín, AJ, Inciarte González, et al |
Revista de Ciencias Sociales |
Commentary/Editorial| Commentaire/Éditorial |
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Parks, AL, Auerbach, et al |
Thrombosis research |
Commentary/Editorial| Commentaire/Éditorial |
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Parks, CD |
Group Dynamics |
Commentary/Editorial| Commentaire/Éditorial |
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Letter: Impact of the COVID-19 pandemic on pharmacist-administered vaccination services |
Patel, C, Dalton, et al |
Research in Social and Administrative Pharmacy |
Commentary/Editorial| Commentaire/Éditorial |
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32943298; IR is an Operational and Financial Hedge for Hospitals during COVID-19 |
Patel, MV, Ahmed, et al |
Journal of Vascular and Interventional Radiology |
Commentary/Editorial| Commentaire/Éditorial |
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COVID-19: A driver for disruptive innovation of the emergency medicine residency application
process |
Pelletier-Bui, A, Franzen, et al |
Western Journal of Emergency Medicine |
Commentary/Editorial| Commentaire/Éditorial |
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Peretto, G, De Luca, et al |
American Heart Journal |
Commentary/Editorial| Commentaire/Éditorial |
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Perrin, DM |
Medical hypotheses |
Commentary/Editorial| Commentaire/Éditorial |
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32910182; Fairly Prioritizing Groups for Access to COVID-19 Vaccines |
Persad, G, Peek, et al |
JAMA - Journal of the American Medical Association |
Commentary/Editorial| Commentaire/Éditorial |
|
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Pfeifer, MD |
Osteologie |
Commentary/Editorial| Commentaire/Éditorial |
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Picard, J, Cornec, et al |
Journal of Hospital Infection |
Commentary/Editorial| Commentaire/Éditorial |
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Pilato, E, Pinna, et al |
Heart and Lung |
Commentary/Editorial| Commentaire/Éditorial |
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COVID-19, credit, lease and tourism-connected contracts in Portugal |
Pinto Oliveira, NM |
Revista de Derecho Civil |
Commentary/Editorial| Commentaire/Éditorial |
|
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Pitts, J |
Journal of Children's Services |
Commentary/Editorial| Commentaire/Éditorial |
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Impairment of the cholinergic anti-inflammatory pathway in older subjects with severe COVID-19 |
Pomara, N, Imbimbo, et al |
Medical hypotheses |
Commentary/Editorial| Commentaire/Éditorial |
|
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32912669; COVID-19: A look from the perspective of bioethics |
Porras-Povedano, M, Santacruz-Hamer, et al |
Atencion Primaria |
Commentary/Editorial| Commentaire/Éditorial |
|
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Caring for patients with
Parkinson's disease during the Covid-19 pandemic |
Price, J, Martin, et al |
Journal of Community Nursing |
Commentary/Editorial| Commentaire/Éditorial |
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COVID-19: An emerging threat to antibiotic stewardship in the emergency department |
Pulia, MS, Wolf, et al |
Western Journal of Emergency Medicine |
Commentary/Editorial| Commentaire/Éditorial |
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Beschreibung von 50 Aachener COVID-19-Patienten mit und ohne ARDS |
Pulz, S |
Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie |
Commentary/Editorial| Commentaire/Éditorial |
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Are nursing
homes covid-19’s “contaminated wells,” and will they receive additional resources? |
Pyenson, B, Grabowski, et al |
American Health and Drug Benefits |
Commentary/Editorial| Commentaire/Éditorial |
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Pyszczynski, T, Lockett, et al |
Journal of Humanistic Psychology |
Commentary/Editorial| Commentaire/Éditorial |
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How to Early Identify and Prevent the SARS-CoV-2 Infection in Children for Families? |
Qiao, MY, Chen, et al |
Frontiers in Pediatrics |
Commentary/Editorial| Commentaire/Éditorial |
|
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Quintin, J |
Canadian Journal of Bioethics |
Commentary/Editorial| Commentaire/Éditorial |
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Peruvian public libraries in the face of the COVID-19 crisis: Services, reflections and challenges |
Quispe-Farfán, GA |
Revista Interamericana de Bibliotecologia |
Commentary/Editorial| Commentaire/Éditorial |
|
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Apocalypse now or overreaction to coronavirus: The global cruise tourism industry crisis |
Radic, A, Law, et al |
Sustainability (Switzerland) |
Commentary/Editorial| Commentaire/Éditorial |
|
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Surgical masks and filtering facepiece (FFP) respirators - A guide |
Rafelt, J |
Dental update |
Commentary/Editorial| Commentaire/Éditorial |
|
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Räisänen, IT, Umeizudike, et al |
Medical hypotheses |
Commentary/Editorial| Commentaire/Éditorial |
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Ramkissoon, H |
Frontiers in Psychology |
Commentary/Editorial| Commentaire/Éditorial |
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Ramos-Zúñiga, R |
Archives of Medical Research |
Commentary/Editorial| Commentaire/Éditorial |
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Emotion analysis of Indians using google trends during COVID-19 pandemic |
Rana, U, Singh, et al |
Diabetes and Metabolic Syndrome: Clinical Research and Reviews |
Commentary/Editorial| Commentaire/Éditorial |
|
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Epidemiology, clinical picture, diagnostics, assessment of the severity of the disease
COVID-19 |
Rassokhin, VV, Samarina, et al |
HIV Infection and Immunosuppressive Disorders |
Commentary/Editorial| Commentaire/Éditorial |
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Recalcati, S, Tonolo, et al |
British Journal of Dermatology |
Commentary/Editorial| Commentaire/Éditorial |
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Rege, SA, Bandekar, et al |
International Journal of Surgery |
Commentary/Editorial| Commentaire/Éditorial |
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The impact of COVID-19 on gender inequality in the labor market and gender-role attitudes |
Reichelt, M, Makovi, et al |
European Societies |
Commentary/Editorial| Commentaire/Éditorial |
|
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Fabry disease patients have an increased risk of stroke in the COVID-19 ERA. A hypothesis |
Reisin, RC, Rozenfeld, et al |
Medical hypotheses |
Commentary/Editorial| Commentaire/Éditorial |
|
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COVID-19: Implications for advanced care planning and end-of-life care |
Reja, M, Naik, et al |
Western Journal of Emergency Medicine |
Commentary/Editorial| Commentaire/Éditorial |
|
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Covid-19: implications for insurer risk management and the insurability of pandemic risk |
Richter, A, Wilson, et al |
GENEVA Risk and Insurance Review |
Commentary/Editorial| Commentaire/Éditorial |
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|
Riemer, K, Ciriello, et al |
European Journal of Information Systems |
Commentary/Editorial| Commentaire/Éditorial |
|
|
|
Reflections on returning
to the front line with the Covid-19 crisis |
Ritchie, G, Ashworth, et al |
Journal of Community Nursing |
Commentary/Editorial| Commentaire/Éditorial |
|
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Evaluating interest in off-label use of disinfectants for COVID-19 |
Rivera, Jessica Malaty, Gupta, et al |
The Lancet Digital Health |
Commentary/Editorial| Commentaire/Éditorial |
|
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Rivera-Franco, M, Saldaña-Gonzalez, et al |
Hematology, Transfusion and Cell Therapy |
Commentary/Editorial| Commentaire/Éditorial |
|
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Survey of Members of the Indian Society of Labour Economics on the COVID-19 Crisis and Employment |
Rodgers, G |
Indian Journal of Labour Economics |
Commentary/Editorial| Commentaire/Éditorial |
|
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Rodriguez, IS, Santos, et al |
Revista da Associacao Medica Brasileira (1992) |
Commentary/Editorial| Commentaire/Éditorial |
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Roe, BE, Bender, et al |
Applied Economic Perspectives and Policy |
Commentary/Editorial| Commentaire/Éditorial |
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Rojas, S |
Chaos, Solitons and Fractals: X |
Commentary/Editorial| Commentaire/Éditorial |
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Editorial: service research in the new (post-COVID) marketplace |
Rosenbaum, MS, Russell-Bennett, et al |
Journal of Services Marketing |
Commentary/Editorial| Commentaire/Éditorial |
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Rowan, NJ, Laffey, et al |
Science of the Total Environment |
Commentary/Editorial| Commentaire/Éditorial |
|
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Rowe, DA, Carter, et al |
Rural Special Education Quarterly |
Commentary/Editorial| Commentaire/Éditorial |
|
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Rozny, S |
Phi Delta Kappan |
Commentary/Editorial| Commentaire/Éditorial |
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Rózyło-Kalinowska, I, Dominiak, et al |
Journal of Stomatology |
Commentary/Editorial| Commentaire/Éditorial |
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Rühli, F, Eppenberger, et al |
Medical hypotheses |
Commentary/Editorial| Commentaire/Éditorial |
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Saini, A |
Social Work with Groups |
Commentary/Editorial| Commentaire/Éditorial |
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Neurotrauma in the time of SARS-COV 2: A checklist for its safe management |
Salazar, LRM, Agrawal, et al |
Journal of Neurosciences in Rural Practice |
Commentary/Editorial| Commentaire/Éditorial |
|
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The United States and China: Deadlocks and Paradoxes of Trade War |
Salitskii, AI, Salitskaya, et al |
Herald of the Russian Academy of Sciences |
Commentary/Editorial| Commentaire/Éditorial |
|
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Samaranayake, L |
Dental update |
Commentary/Editorial| Commentaire/Éditorial |
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Rethinking the governance of the 2030 agenda for sustainable development in the COVID-19 era |
Santos-Carrillo, F, Fernández-Portillo, et al |
Sustainability (Switzerland) |
Commentary/Editorial| Commentaire/Éditorial |
|
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Reflection of epidemics on turkish minstrel poetry: The case of novel corona-virus
(covid-19) |
Saraç, Ö |
Milli Folklor |
Commentary/Editorial| Commentaire/Éditorial |
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Patient isolation pods for the evacuation of COVID-19 infected patients - Is this the answer? |
Sasidharan, S, Singh, et al |
Journal of Anaesthesiology Clinical Pharmacology |
Commentary/Editorial| Commentaire/Éditorial |
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Sathish, T, Cao, et al |
Primary Care Diabetes |
Commentary/Editorial| Commentaire/Éditorial |
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Imaging diagnostics and pathology in sars-cov-2-related diseases |
Scimeca, M, Urbano, et al |
International Journal of Molecular Sciences |
Commentary/Editorial| Commentaire/Éditorial |
|
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90 days in 2020: Covid-19 exposes health
equity opportunities |
Scott, BC |
American Health and Drug Benefits |
Commentary/Editorial| Commentaire/Éditorial |
|
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Scrivner, C, Johnson, et al |
Personality and Individual Differences |
Commentary/Editorial| Commentaire/Éditorial |
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Impact of COVID-19 on persons in correctional facilities – a commentary |
Seal, DW |
Health Behavior and Policy Review |
Commentary/Editorial| Commentaire/Éditorial |
|
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Seifu Estifanos, A, Alemu, et al |
BMJ Global Health |
Commentary/Editorial| Commentaire/Éditorial |
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Seiwald, J, Polzer, et al |
Journal of Public Budgeting, Accounting and Financial Management |
Commentary/Editorial| Commentaire/Éditorial |
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Natural molecules having anti-SARS-CoV activity-cannot they be effective against SARS-CoV-2? |
Semwal, DK, Chauhan, et al |
Current science |
Commentary/Editorial| Commentaire/Éditorial |
|
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Underestimation of the covid-19 burden: Interpreting
the puzzling numbers |
Seshadri, MS, John, et al |
Economic and Political Weekly |
Commentary/Editorial| Commentaire/Éditorial |
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Sethuraman, U, Stankovic, et al |
Burns |
Commentary/Editorial| Commentaire/Éditorial |
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Preventing exposure to COVID-19 in the operation theatre and intensive care unit |
Setlur, R, Jaiswal, et al |
Journal of Anaesthesiology Clinical Pharmacology |
Commentary/Editorial| Commentaire/Éditorial |
|
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Management of Acute Kidney Injury in Coronavirus Disease 2019 |
Shaikh, S, Matzumura Umemoto, et al |
Advances in Chronic Kidney Disease |
Commentary/Editorial| Commentaire/Éditorial |
|
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Shannon, S |
Dental update |
Commentary/Editorial| Commentaire/Éditorial |
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Entangled Time Hops: Doomsday Clocks, Pandemics, and Qualitative Research’s Responsibility |
Shelton, SA |
Qualitative Inquiry |
Commentary/Editorial| Commentaire/Éditorial |
|
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Reflections on the management of a coronavirus disease 2019 patient with refractory
hyperglycemia |
Shen, Z, Xie, et al |
Chinese Journal of Endocrinology and Metabolism |
Commentary/Editorial| Commentaire/Éditorial |
|
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Positive, again! What to make of “re-positive” SARS-CoV-2 molecular test results |
Simon, V, van Bakel, et al |
EBioMedicine |
Commentary/Editorial| Commentaire/Éditorial |
|
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“Gendering” contamination: physical, social and moral taint in the context of COVID-19 |
Simpson, R, Morgan, et al |
Gender in Management |
Commentary/Editorial| Commentaire/Éditorial |
|
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32954708; Analysis of Host Cell Receptor GRP78 for Potential Natural Reservoirs of SARS-CoV-2 |
Sirakov, I, Bakalov, et al |
Journal of epidemiology and global health |
Commentary/Editorial| Commentaire/Éditorial |
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Slamnik-Kriještorac, N, De Resende, et al |
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Commentary/Editorial| Commentaire/Éditorial |
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Smart, N |
Colorectal Disease |
Commentary/Editorial| Commentaire/Éditorial |
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Smith, N, Hughes, et al |
Journal of the Intensive Care Society |
Commentary/Editorial| Commentaire/Éditorial |
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COVID-19 in Australia: Impacts on Separated Families, Family Law Professionals, and Family Courts |
Smyth, BM, Moloney, et al |
Family Court Review |
Commentary/Editorial| Commentaire/Éditorial |
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Sobol, SE, Preciado, et al |
Otolaryngologic clinics of North America |
Commentary/Editorial| Commentaire/Éditorial |
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Cutaneous manifestations among COVID-19 patients: Tip of an iceberg? |
Sood, M, Sharma, et al |
Sri Lanka Journal of Child Health |
Commentary/Editorial| Commentaire/Éditorial |
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COVID-19 pandemic: A multifaceted challenge for science and healthcare |
Sorbello, M, Greif, et al |
Trends in Anaesthesia and Critical Care |
Commentary/Editorial| Commentaire/Éditorial |
|
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32940676; COVID-19 and the Slide Backward for Women in Academic Medicine |
Spector, ND, Overholser, et al |
JAMA network open |
Commentary/Editorial| Commentaire/Éditorial |
|
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COVID-19 and the regulatory
considerations for vaccine development |
Speder, B |
Regulatory Rapporteur |
Commentary/Editorial| Commentaire/Éditorial |
|
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Preparation and redeployment of house staff during a pandemic |
Spiegelman, J, Praiss, et al |
Seminars in perinatology |
Commentary/Editorial| Commentaire/Éditorial |
|
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32917397; A Bronx tale: Exposure, containment and care on inpatient psychiatry units
during COVID-19 |
Spitzer Sverd, S, Gardner, et al |
General hospital psychiatry |
Commentary/Editorial| Commentaire/Éditorial |
|
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COVID-19: The unseen threat for the healthcare professionals |
Sriganesh, K, Rao, et al |
Journal of Neurosciences in Rural Practice |
Commentary/Editorial| Commentaire/Éditorial |
|
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Solid-organ transplant surgeries in era of COVID-19 pandemic: How to go about it? |
Srivastava, D, Solanki, et al |
Journal of Anaesthesiology Clinical Pharmacology |
Commentary/Editorial| Commentaire/Éditorial |
|
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Stark, N, Kerrissey, et al |
Western Journal of Emergency Medicine |
Commentary/Editorial| Commentaire/Éditorial |
|
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On Leadership: Who are the real experts in your school system? |
Starr, JP |
Phi Delta Kappan |
Commentary/Editorial| Commentaire/Éditorial |
|
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Local currencies versus the level of economic security of the region during the COVID-19 period |
Stępnicka, N, Wiączek, et al |
WSEAS Transactions on Business and Economics |
Commentary/Editorial| Commentaire/Éditorial |
|
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Trace together: Pandemic response, democracy, and technology |
Stevens, H, Haines, et al |
East Asian Science, Technology and Society |
Commentary/Editorial| Commentaire/Éditorial |
|
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Strand, NH, Maloney, et al |
Journal of clinical anesthesia |
Commentary/Editorial| Commentaire/Éditorial |
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Subbarao, K, Mordant, et al |
European journal of immunology |
Commentary/Editorial| Commentaire/Éditorial |
|
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32683337; Pediatric Inflammatory Multisystem Syndrome Temporally Associated With COVID-19 |
Sudhakar, M, Jindal, et al |
Indian pediatrics |
Commentary/Editorial| Commentaire/Éditorial |
|
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Takayama, K |
Higher Education Research and Development |
Commentary/Editorial| Commentaire/Éditorial |
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Takewaki, I |
Frontiers in Built Environment |
Commentary/Editorial| Commentaire/Éditorial |
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Talotta, R, Robertson, et al |
World Journal of Clinical Cases |
Commentary/Editorial| Commentaire/Éditorial |
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Torres, I, López-Cevallos, et al |
BMJ Global Health |
Commentary/Editorial| Commentaire/Éditorial |
|
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Tulek, N, Gonullu, et al |
Indian pediatrics |
Commentary/Editorial| Commentaire/Éditorial |
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Turcios-Casco, M, Cazzolla Gatti, et al |
Biodiversity and Conservation |
Commentary/Editorial| Commentaire/Éditorial |
|
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Ubhi, A, Nandhra, et al |
Dental update |
Commentary/Editorial| Commentaire/Éditorial |
|
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32639391; The Adverse Impact of COVID-19 on Health Care Providers: Time to Start Measuring |
Urdaneta, F, Stacey, et al |
Anesthesia and Analgesia |
Commentary/Editorial| Commentaire/Éditorial |
|
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The mental health impact of COVID-19 on pre-registration nursing students in Australia |
Usher, K, Wynaden, et al |
International Journal of Mental Health Nursing |
Commentary/Editorial| Commentaire/Éditorial |
|
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Detection and monitoring of the asymptotic COVID-19 patients using IoT devices and sensors |
V N, RK, M, et al |
International Journal of Pervasive Computing and Communications |
Commentary/Editorial| Commentaire/Éditorial |
|
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Vangelista, L, Secchi, et al |
Frontiers in Molecular Biosciences |
Commentary/Editorial| Commentaire/Éditorial |
|
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The Colombia mesures to mitigate the consequences of the COVID-19 under civil
law |
Vargas Brand, IN |
Revista de Derecho Civil |
Commentary/Editorial| Commentaire/Éditorial |
|
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Towards characterized convalescent plasma for COVID-19: The dose matters |
Verkerke, HP, Maier, et al |
EClinicalMedicine |
Commentary/Editorial| Commentaire/Éditorial |
|
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32945641; COVID-19 associated viral myocarditis: does it exist? |
Verma, V, Sondhi, et al |
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace |
Commentary/Editorial| Commentaire/Éditorial |
|
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Vijay, A, Somnath, et al |
The journal of the Royal College of Physicians of Edinburgh |
Commentary/Editorial| Commentaire/Éditorial |
|
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Villa, ÍM |
Revista de Derecho Civil |
Commentary/Editorial| Commentaire/Éditorial |
|
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Vinuesa, R, Theodorou, et al |
Results in Engineering |
Commentary/Editorial| Commentaire/Éditorial |
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Vlaar, AlexanderPJ, de Bruin, et al |
The Lancet Rheumatology |
Commentary/Editorial| Commentaire/Éditorial |
|
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Virtual Conferences in Times of COVID-19: Embracing the Potential [Young Professionals] |
Vogel, J, Ajoudani, et al |
IEEE Robotics and Automation Magazine |
Commentary/Editorial| Commentaire/Éditorial |
|
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The vulnerability of nursing home residents to the Covid-19 pandemic |
Wagner, EH |
International Journal of Care Coordination |
Commentary/Editorial| Commentaire/Éditorial |
|
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Wang, F, Zhang, et al |
Frontiers of Business Research in China |
Commentary/Editorial| Commentaire/Éditorial |
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Wang, L, DeLaquil, et al |
Higher Education Research and Development |
Commentary/Editorial| Commentaire/Éditorial |
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Wang, X, Xiao, et al |
Public Money and Management |
Commentary/Editorial| Commentaire/Éditorial |
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Watters, Y, Northey, et al |
Journal of Family Psychotherapy |
Commentary/Editorial| Commentaire/Éditorial |
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Wehner, MR, Li, et al |
JAMA network open |
Commentary/Editorial| Commentaire/Éditorial |
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A Sonographer’s Step-by-Step Approach for Preventing Transmission of COVID-19 |
Wessner, CE, Nelson, et al |
Journal of Diagnostic Medical Sonography |
Commentary/Editorial| Commentaire/Éditorial |
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Williams, N, Winters, et al |
ANZ Journal of Surgery |
Commentary/Editorial| Commentaire/Éditorial |
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Nurse Leader |
Commentary/Editorial| Commentaire/Éditorial |
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Winet, K, Winet, et al |
Journal of Business and Technical Communication |
Commentary/Editorial| Commentaire/Éditorial |
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Wiwanitkit, V |
Cardiology in the young |
Commentary/Editorial| Commentaire/Éditorial |
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32954707; The Precious Commodity of Time and Sub-Saharan Africa's Success in Keeping COVID-19
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Wojcicki, JM |
Journal of epidemiology and global health |
Commentary/Editorial| Commentaire/Éditorial |
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Drafting Pandemic Policy: Writing and Sudden Institutional Change |
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Journal of Business and Technical Communication |
Commentary/Editorial| Commentaire/Éditorial |
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Journal of Property Investment and Finance |
Commentary/Editorial| Commentaire/Éditorial |
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Indian Journal of Surgical Oncology |
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Information Systems Management |
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Appendix: Process and definitions.
A daily search for new publications is conducted in PubMed, Scopus,
BioRxiv and MedRxiv, SSRN,
Research Square,
arXiv for all publications related to COVID-19 disease or SARS-CoV-2 using the search terms (COVID-19 OR SARS-CoV-2
OR "novel CoV" OR "novel coronavirus" OR nCoV) adapted to each database. The capture is cross-referenced with publication announcements on the COVID-19 dashboards set up by a number of publishers and google. Publishers include
Lancet,
Elsevier,
The New England Journal of Medicine,
BMJ, Wiley,
Springer Nature, ChinaCDCweekly.
Additionally the database is cross-referenced with other literature scans e.g.
WHO publication list and activities by collaborators. Members of the Emerging Sciences group develop 1 -2 point summaries of each publication. Please email Lisa Waddell for additional information:
Lisa.Waddell@canada.ca.
References are compiled in a reworks database that has citations since the beginning of the outbreak. All references can be accessed at this
link and by the categories listed below. The daily scan has also been compiled in an excel sheet and copies can be provided upon request or
accessed
here.
Category Definitions:
Modelling/ prediction: Predictive modeling is a process that uses data mining and probability
to forecast outcomes. Each model is made up of a number of predictors, which are variables that are likely to influence future results.
Epidemiology:
the branch of medicine which deals with the incidence, distribution, and possible control of diseases and other factors relating to health. Includes Ro, attack rates, case number doubling time, case fatality
rate, serial interval, clinical attack rate, asymptomatic fraction, proportion of asymptomatic and infective*
Transmission: The passage of a pathogen causing communicable disease from an infected host
to an uninfected host via direct or indirect routes.
Clinical data
of cases: Includes clinical parameters such as incubation period, latent period, period of communicability, duration of illness, duration of hospitalization, host risk factors, as well as clinical profiles of patients; presenting symptoms, symptoms over
course of illness, sequelae, comorbidities.*
Surveillance: Public health surveillance is the continuous, systematic collection, analysis and
interpretation of health-related data. Surveillance data will likely be number of cases suspected/confirmed, number of deaths, number recovered. *
Coronavirology: All research relating to the virus; its characteristics, genetic make-up, phylogenetic
analyses
Diagnostics / Pathogen detection:
All studies on identification of the virus; culture, PCR, antibody/antigen tests etc.
Therapeutics:
Studies of substances that may be used to treat infected hosts including passive immunization products.
Vaccine Research:
Studies of vaccine candidates to prevent infection with 2019-nCoV including clinical trials.
Public Health Priorities:
These citations will focus on what the current research priorities are and/or where knowledge gaps exist.
Public Health interventions*:
Any study evaluating how effective a public health intervention is or maybe (in the case of a predictive model).
Public Health response:
These papers are typically overviews of past and current activities, they often also identify knowledge gaps and suggest future activities or objectives.
Infection Prevention and Control/
Prévention et contrôle des infections (IPAC/PCI): Any research on the effectiveness of IPC interventions should also be tagged as IPC
Health care Response:
This foci would include a description of activities to deal with 2019-nCoV cases including, but not limited to: set up of a special emergency multi-disciplinary intensive care team; Bed and medical equipment preparation/ stock piling supplies; Education
and training of staff; Early case recognition and classification of disease severity.
Economics: papers discussing/ forecasting the economics of COVID-19 pandemic.
Zoonotic:
all literature discussing the transmission to and from or occurrence of naturally acquired SARS-COV-2 infection in animals.
Review Literature:
All articles that summarize the published literature can be tagged as a review. This includes systematic review, meta-analysis, scoping review, overviews, umbrella reviews*
Commentary/Editorial:
For commentaries, editorials, letters to the editor, other types of opinion pieces where there is no new data collected by the author or analysis conducted by the author, please tag these within the commentary category.
News articles that have not scientific information.
*Lists are not exhaustive
Annexe: Processus et définitions.
Une recherche quotidienne des nouvelles publications est effectuée dans PubMed, Scopus,
BioRxiv and MedRxiv,
SSRN,
Research Square,
arXiv
pour toutes les publications relatives à la maladie COVID-19 ou au SRAS-CoV-2 en utilisant les termes de recherche (COVID-19 OU SARS-CoV-2 OU « novel CoV » OU « novel coronavirus » OU nCoV). La saisie renvoie à des annonces de publication
sur les tableaux de bord du nCoV mis en place par un certain nombre d'éditeurs et par Google. Parmi les éditeurs figurent
Lancet,
Elsevier,
The New England Journal of Medicine,
BMJ,
Wiley,
Springer Nature,
ChinaCDCweekly. En outre, la base de données renvoie à d'autres survols de publications, e.g.
la liste des publications de l'OMS,
et à des activités des collaborateurs. Les membres du groupe scientifique émergent préparent des résumés en 1 ou 2 points de chaque publication. Pour en savoir plus, veuillez envoyer un courriel à Lisa Waddell au :
Lisa.Waddell@canada.ca.
Les références sont compilées dans une base de données Refworks qui contient des citations depuis le début de l'épidémie. Toutes les références sont accessibles à partir de ce
lien et par les catégories énumérées ci-dessous. L'analyse quotidienne a également été compilée
dans une feuille Excel et des copies peuvent être fournies sur demande ou consultées
ici.
Définitions des catégories :
Modélisation / prédiction :
La modélisation prédictive est un processus qui utilise l'exploration de données et la probabilité pour prévoir les résultats. Chaque modèle est composé de plusieurs prédicteurs, qui sont des variables susceptibles d'influencer les résultats futurs.
Épidémiologie :
Branche de la médecine qui traite de l'incidence, de la répartition et du contrôle éventuel des maladies et d'autres facteurs liés à la santé. Comprend le taux de reproduction de base (Ro),
les taux d'attaque, le temps de doublement du nombre de cas, le taux de létalité, l'intervalle sériel, le taux d'attaque clinique, la fraction asymptomatique, la proportion de cas asymptomatiques et infectieux*.
Transmission :
Passage d'un agent pathogène causant une maladie transmissible d'un hôte infecté à un hôte non infecté par des voies directes ou indirectes.
Données cliniques
des cas : Comprend les paramètres cliniques tels que la période d'incubation, la période de latence, la période de contagiosité, la durée de la maladie, la durée de l'hospitalisation, les facteurs de risque de l'hôte, ainsi que les profils
cliniques des patients; les symptômes présentés, les symptômes au cours de la maladie, les séquelles, les comorbidités.*
Surveillance : La surveillance
de la santé publique est la collecte, l'analyse et l'interprétation continues et systématiques de données relatives à la santé. Les données de surveillance concerneront probablement le nombre de cas suspects / confirmés, le nombre de décès, le nombre de personnes
guéries. *
Coronavirologie :
Toutes les recherches relatives au virus, ses caractéristiques, sa constitution génétique et les analyses phylogénétiques.
Diagnostics / Détection d'agents pathogènes :
Toutes les études sur l'identification du virus : culture, PCR, tests de dépistage d'anticorps ou d’antigènes, etc.
Thérapeutique :
Étude des substances pouvant être utilisées pour traiter les hôtes infectés, y compris les produits d'immunisation passive.
Recherche sur les vaccins : Études des candidats à la
vaccination pour prévenir l'infection par le 2019-nCoV, y compris des essais cliniques.
Priorités de santé publique :
Ces citations porteront sur les priorités actuelles de recherche et/ou sur les lacunes dans les connaissances.
Interventions de santé publique* :
Toute étude évaluant l'efficacité (réelle ou possible) d'une intervention de santé publique (dans le cas d'un modèle prédictif).
Réponse de la santé publique :
Ces articles sont généralement des aperçus des activités passées et actuelles, qui identifient souvent les lacunes dans les connaissances et suggèrent des activités ou des objectifs futurs.
Prévention et contrôle des infections/Infection Prevention and Control (PCI/IPAC) :
Les recherches sur l'efficacité des interventions en PCI doivent également être marquées comme PCI.
Réponse des soins de santé :
Ce point comprendrait une description des activités pour traiter les cas de 2019-nCoV, notamment : mise en place d'une équipe multidisciplinaire spéciale de soins intensifs d'urgence; préparation des lits et des équipements médicaux
/ stockage des fournitures; sensibilisation et formation du personnel; reconnaissance précoce des cas et classification de la gravité de la maladie.
Modèle animal:
Zoonotic:
all literature discussing the transmission to and from or occurrence of naturally acquired SARS-COV-2 infection in animals.
Économie: documents discutant / prévoyant l'économie de la pandémie de COVID-19
Revue de la documentation :
Tous les articles qui résument les documents publiés peuvent être marqués comme une revue. Cela comprend les revues systématiques, les méta-analyses, les études de la portée, les aperçus, les examens généraux*.
Commentaires/Éditorial :
Pour les commentaires, éditoriaux, lettres à la rédaction, autres types d'articles d'opinion pour lesquels aucune nouvelle donnée n'est collectée ou aucune analyse n'est effectuée par l'auteur, veuillez les marquer dans la catégorie des
commentaires.
journaux
Articles de presse qui n'ont pas d'informations scientifiques.
* Les listes ne sont pas exhaustives